Cutlassfish (Trichiurus lepturus) is a cosmopolitan coastal species fished in warm and warm-temperate waters around the world. The occurrence of cutlassfish near thermal fronts in this latitudinal range indicates that oceanographic and biological interactions can be critical to define optimum environmental conditions for this species(Nakamura and Parin, 1993). Cutlassfish is more abundant at temperatures of over 16°C and in the 40-120 m depth range. From late spring to fall, juveniles of 5-30 cm total length (TL) have been found in coastal waters, subadults (TL 30-70 cm) mainly in inner shelf waters and adults (TL >70 cm) in coastal, inner, and outer shelf waters (Martins and Haimovici, 1997). The cutlassfish is one of the most representative…show more content… Many of these bioactive peptides have been used to develop novel drugs and healthy food material with a higher nutritional value containing numerous kinds of biological effects such as antioxidative, antihypertensive, antimicrobial, anti-inflammatory, and immunomodulatory properties. Fish proteins can also be utilized in such applications with the use of enzyme hydrolysis technology to produce pharmaceuticals and functional food products. Protein hydrolysates prepared from various fish sources including capelin, mackerel, yellowfin sole, Alaska pollack, Atlantic salmon, hoki, conger eel, and scad have been reported to contain biofunctional peptides (Amarowicz and Shahidi, 1997, Gu, et al., 2011, Je, et al., 2005, Jiang, et al., 2014, Jun, et al., 2004, Kim, et al., 2007, Kumar, et al., 2012, Ranathunga, et al., 2006). Among them, many of the fish protein hydrolysates possess antioxidant and angiotensin-I converting enzyme (ACE) inhibition activities. Oxidative stress caused by free radicals generated in live tissues due to various kinds of metabolic activities are a major cause of many chronic diseases conditions such as diabetes, cardiovascular disease, neurodegenerative disorders, and cancer (Kang, et al., 2015). Radicals, such as the superoxide anion (O2•-) and hydroxyl (HO•), are highly unstable, whereas they rapidly react with essential
