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Depression and Psychotropic Medication

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Depression and Psychotropic Medication
PD
Psychopharmacology
CHMC 640

Depression and Psychotropic Medication Depression is often defined as a mood disorder that causes a persistent feeling of sadness and loss of interest that impacts the way a person thinks, acts, and feels and can have an impact on one’s physical and mental well-being. It is estimated that depression affects 1 out of 10 Americans and that 80% of people exhibiting symptoms re not receiving any form of treatment (http://www.healthline.com). Other statistics revealed that individuals exhibiting symptoms of depression are more likely to have a history of being obese, having heart disease, strokes, suffer from sleep disorders, have lower education, less access to medical care, are unemployed, and recently divorced. These biopsychosocial factors that lead to the onset of depression can also be impacted by such things as age, gender, and ethnicity. While such symptoms and factors of depression can be treated in many different ways, studies have proven that between 60-80% of all cases involving depression can successfully be treated by combining psychotherapy and pharmacological constructs (http://www.healthline.com), the latter which shall be explored in greater detail.
History of Medication
Although plant extracts such as opium, thorn apple St. Johns wort, Henbane, Indian hemp, deadly nightshade, hypericum oil, alcohol, caffeine, cannabis and other natural remedies have been used for past 3000 years treat depression, it wasn’t until 1957 that the first tricyclic antidepressant (TCA) known as imipramine was discovered by Ronald Kuhn and later in the same year the first Monoamine oxidase inhibitors (MAOIs), iproniazide, was introduced by Loomer, Saunders, and Kline (Fitzpatrick, 2010, p. 3), which initially was used to treat tuberculosis, but discovered that it increased mood and physical

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