...Ethical Health Care Issues In 1953, two scientists James Watson and Francis Click published the description of the double helix structure of the DNA. Little did they know that voyage from the double helix to The Human Genome Project (HGP) would become a reality. Fifty years later in 2003, National Institute Health accomplished mapping of 32,000 genes of the human genome. Gene mapping was a significant research that enabled researchers to focus on gene specific diseases and birth defects. More than 1000 research projects started inward voyage discovery of human kind rather outward exploration of the planets. Clinical research involving human beings have greater potential for risk of misusing the technology. Potential for misusing the genetic research and fear of unknown long term effects on the successive generations have sparked bioethics debates. Like abortion, gene mapping is a very controversial subject and both sides have strong views. For example, should a woman abort the pregnancy based on the abnormal genetic screening results? Genetic technology provides an enormous power within our grips and with this enormous power comes following the ethical standards. Ethical standards should be followed involving human subjects. Genetic screening standards should align with four ethical principles of: • Respect for the human autonomy, dignity, and obtaining informed consent • Genetic screening should cause the minimal amount of harm to the subject • Provides maximum benefit to...
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...change our fate, or even just ensure a better future for your off-spring? Each of us possesses genetic material that is built upon a code that makes every organism unique. The technology to alter our genetic make-up is getting closer by the minute. I am referring to The Human Genome Project. What is a genome and what is this project you ask? The National Institute of Health or NHI defines a genome as: A genome is an organism’s complete set of DNA, including all of its genes. Each genome contains all of the information needed to build and maintain that organism. In humans, a copy of the entire genome—more than 3 billion DNA base pairs—is contained in all cells that have a nucleus. Basically, it is a map of how our DNA is assembled. DNA is a compound that is and the NHI gives this definition of DNA, “DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA.” There are four kinds of DNA and depending on how they are arranged, defines your genetic make-up. This arrangement forms a map of sorts, and this map is the genome. Ever since DNA was discovered in 1953, scientists have wanted to make the human genome (Genetics Home Reference, 2013). Ultimately it is suggest we will use gene modification to improve human life. Proponents of The Human Genome Project or THGP argue that predicting our genetic make-up will improve the quality our lives while others argue we are opening a Pandora’s Box...
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...Genetic counseling Above the last few years, research and developments in genetics have exceeded our potentials and have changed the approach of thinking of us about health. We know genetics has been involve in newborn screening, pre and postnatal diagnosis, hematological disorders and solid tumour, nearly every disorder is subject in by an individual’s genetic material. Consequently, it is important to consider the effect of genetics for any disorder during a patient’s life. Each disorders have different genetic pattern, and how much genes contribute to disease remains to be learned. Advance development in understanding the genetic changes in these disorders allows early diagnostic tests, advance treatments, or interventions to prevent disease...
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...profiling results is a controversial topic amongst individuals, families, doctors, and employees. Individuals should possess ownership of their genetic information. From a legal, ethical, and social standpoint, it is wrong to force someone, unwillingly, into sharing their DNA. Socially, the release of one’s DNA may cause tension and angst between family members. Legally, it is unrealistic to assume that shared genetic information will always end up in the right hands. Many argue over who is legally responsible for test results. Aside from laws regarding doctor patient confidentiality, individuals should the legal owner of their results....
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... * ------------------------------------------------- Version List ------------------------------------------------- Recent History * ------------------------------------------------- 2006 13.386 New 2006 c 253 s 1 * ------------------------------------------------- 2013 Subd. 3 Amended 2013 c 82 s 3 * ------------------------------------------------- 2012 Subd. 4 New 2012 c 292 art 4 s 1 13.386 TREATMENT OF GENETIC INFORMATION HELD BY GOVERNMENT ENTITIES AND OTHER PERSONS. § Subdivision 1.Definition. (a) "Genetic information" means information about an identifiable individual derived from the presence, absence, alteration, or mutation of a gene, or the presence or absence of a specific DNA or RNA marker, which has been obtained from an analysis of: (1) the individual's biological information or specimen; or (2) the biological information or specimen of a person to whom the individual is related. (b) "Genetic information" also means medical or biological information collected from an individual about a particular genetic condition that is or might be used to provide medical care to that individual or the individual's family members. § Subd. 2.Private...
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...| | | | | | | Genetic IssueEmploying Genetic Markers to Improve Diagnosis | | | | | | | | | | | | | | | | | | | | | | | | Melanie Fortin | Genetic Issue Employing Genetic Markers to Improve Diagnosis I chose a topic related to genetic markers and its use to improve diagnosis of tumors. (www.ncbi.nlm.nih.gov/pmc/articles/PMC327311/-EmployingGeneticMarkerstoImproveDiagnosisofThyroidTumorFineNeedleBiopsy)Dec2011. This topic is an important topic in the world of public health at the moment. However, it really is a topic that hit close to home recently. I was diagnosed with a right thyroid nodule in February. Since it was large enough, it required a fine needle aspiration. This prompted me to further investigate my options once I got the results that it was highly suspicious for Hurthle cell neoplasm. While reading this article, I wanted to better understand if I had other options than surgical removal of my thyroid to obtain the definite benign/malignant diagnosis. This well written article raises the awareness of how commonly the public has to undergo surgical removal of a nodule in order to get a definite diagnosis. Genetic markers have been identified to aid in the diagnosis of certain of these thyroid carcinomas. The study demonstrated that “71% of unnecessary surgical procedure could be avoided”, but that also “22% of cancers would be missed”. Although I did not know much about genetic markers as it related to thyroid...
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...“Inappropriate genetic testing can threaten individual autonomy, privacy, and confidentiality and lead to various types of genetic stigmatization and discrimination without any commensurate benefit for the individual tested,” (Brandt; Rauf, 2004). When Burlington Northern Santa Fe Railway (BNSF) tested their employees without the employees knowing about it, the Equal Employment Opportunity Commission (EEOC) stepped in and cited that BNSF violated the employee’s equal rights through discrimination and the employee’s rights of privacy. These actions “raise serious concerns that such testing could pose a significant threat to workers' privacy, autonomy, and dignity. Thus, defining the ethically, legally, and socially appropriate and inappropriate uses of genetic testing in the workplace,” (DEHS, 2001) presents a major breach in a workers legal right to privacy. One hundred and twenty-five BNSF employees filed on-the-job injury claims citing carpal tunnel syndrome (CTS) for “years of repetitive activity such as wielding a wrench or operating a jackhammer,” (Lehrer, 2001; UNK, 2001). While investigating these claims, BNSF medical doctor required further testing of 20 employees (UNK, 2001). The medical company pulled blood for genetic testing without telling the BNSF employees what kind of test that they were performing, (Mahanna, 2001; Schafer, 2001; BNSF, 2002; Lehrer, 2001; Lewin, 2002). One employee refused to submit to the tests and BNSF threatened to terminate his job (Lewin;...
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...remain very controversial. In this paper we will explore the use of genetic trait testing, access to genetic information as well as the issue of vaccinating or not. With regards to bioethical related data the accessing, storing, gathering, and sharing medical data for the purpose of using the data for the scientific purpose of research is still a controversial issue in the scientific community. There is no basic problem with sharing medical data electronically, with the implementation of EHR, electronic health records. However, there is yet to be formal ethical guidelines established for the use of this data in the biological sciences community. There have been guidelines introduced for developing ethical principles with the ultimate goal of winning over the scientific community to incorporate the use of this data into their existing code of ethics. The scientific community has an obligation to share this data, if permitted by the patient, for research purposes. It also can be a major factor that could increase the trust of the public with regards to scientific research. Society also had concerns about employers having access to genetic information. (Duke & Porter, 2013) With the Genetic Information Nondiscrimination Act of 2008 (GINA) employers are prohibited to use this information for the purpose of employment selection, firing or promotion. GINA also prohibits insurance companies from using genetic information as a means to accept or deny an individual coverage or charge...
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...Modified Animals Animals with special characteristics and traits have been cross breed through sexual reproduction for many years, but with the increasing of technology, scientists can now create animals directly from gene modification. Genetic modification is described as the science used to change the characteristics of an organism genetic component and manipulate the deoxyribonucleic acid structures using technology. “Deoxyribonucleic acid (DNA) is nucleic acid that carries hereditary information about traits of an organism and carries the instructions for all the characteristics that organism inherits, it consist of two chain of nucleotides twisted into a double helix” (Starr, C., Evers, C. A., Starr, L. 2013). Genetically modified animals are made from embryonic stem cells carrying two copies of gene one from the male and the other from the female. Scientists cut and join DNA from different sources then transfer it into the organism so it has the modified genes and from that procedure, a new set of genes is created. Manipulating the DNA and transforming certain gene to create a new life is called recombinant DNA (rDNA) technique. Scientists use recombinant DNA technique to modify the chemical inside the nucleus of a cell which carries genetic instructions from one organism to another and to improve specific characteristics of an animal or to introduce a new trait that is resistant to diseases and may enhance the growth of animals. In addition, the changes introduced to that...
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...Genomic Health, Inc. External Analysis Report Presented to: Dr. Karen Middleton Texas A&M University – Corpus Christi Submitted by: Jacinda Martinez Jennifer Kindred Shiwei Chen Yang Gao Ying Zhang October 16, 2013 TABLE OF CONTENTS LIST OF TABLES iii EXECUTIVE SUMMARY iv INTERNAL ENVIRONMENT 1 MISSION STATEMENT 1 FINANCIAL RATIO ANALYSIS 1 STOCK ANALYSIS 2 VRIO TEST 3 CORE COMPETENCIES 3 Research & Development 3 Patents 5 Management Team 6 Reputation 7 CURRENT BUSINESS AND CORPORATE LEVEL STRATEGY 9 Business Level Strategy 10 Corporate Level Strategy 10 STRENGTHS AND WEAKNESSES 13 Strengths 10 Weaknesses 10 SWOT MATRIX 13 REFERENCES 25 LIST OF TABLES (need to redo these for internal tables) Table 1: Strategic Group Dimensions 13 Table 2: Liquidity Ratios 14 Table 3: Leverage Ratios 15 Table 4: Activity Ratios 15 Table 5: Profitability Ratios 16 Table 6: Growth Ratios 17 Table 7: Stock Analysis 18 MISSION STATEMENT Genomic Health is dedicated to addressing the difficult challenges of cancer treatment by utilizing genomics to help physicians and patients choose the most appropriate treatment options with optimal confidence. Table 1: Nine Components of a Mission Statement Customers | Yes | Products/Services | Yes | Markets | Yes | Technology | Yes | Survival, Growth, Profitability...
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...Public Health and Health Care HCS/535 Public Health And Health Care Public health agencies can affect one’s workplace in many ways. An organization that does research on developmental health issues has to deal with the Department of Developmental Services or DDS on a regular basis. The Department of Developmental Services is a division of the Health and Human Services and helps create opportunities for people with intellectual disabilities. The DDS plays a major role in public health of the community of developmental disabilities. The role of public agencies in health as a whole helps provide care for the disabled, advocate for social rights and better health for the communities. They also help create a network of workers that are responsible for ensuring that individuals with developmental disabilities have their chance in society and are treated fair and with dignity. The Department of Developmental Services * The Department of Developmental Services is dedicated to creating innovation as well as genuine opportunities for individuals with intellectual disabilities to participate fully and meaningfully in, and contribute to their communities as valued members (HHS, n.d.). The DDS have many principles to help guide them in accomplishing their goal. Some of those principles include respecting each individual by promoting the human and civil rights, and try to prevent neglect and abuse. Also the DDS helps enhance public awareness about people with intellectual disabilities...
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...and future hunger controversy is what inspired biotechnology and genetic engineering. The hopes of solving the food problem of this world’s growing population has brought about the genetic engineering or genetically modified crops in farming. Even though some proponents that genetically modified foods could be beneficial to the world, to include taste and quality, and resistance to disease, the truth is yet to be recognized unequivocally. There are thousands of questions to be answered and further research to be done. Public awareness is equally necessary and the reality of food and crop engineering and distributing is also yet to be complete. This paper will examine if the consumption of genetically engineered foods is good for human health, the agriculture and the world’s food supply, genetically engineering involving nature, the positive and negative aspects, and the food security and alternatives. II. Human Health a) Public Awareness b) Taste c) Promises III. Agriculture and Food Supply a) Pollution of crops b) Does more or less need to be done with genetic modification c) Too much or too less will cause hunger IV. Nature a) Will species be harmed? Will land be harmed? V. Positive and Negative Effects a) Pros b) Cons VI. Food Security/Alternatives a) Alternative Routes b) Organic Farming VII. Conclusion There are great alternatives to genetic engineering; there will always be surplus requirements. The nation...
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...interconnected, i.e. mere studies of the way in which concepts are in fact informed by moral opinions and social values is not siffucient. Outright normative analyses of underlying ethical views need to underpin suggestions with regard to the way in which central concepts should be employed in policy contexts. This has been recognised in research on the basic ethical issue of what should be seen as the basic determinant of the quality of life or well-being (Brülde 1998, 2006), as well as research on applied ethics of relevance for disability (Brülde 2003; Munthe 1996, 1999; Juth 2005; Juth & Munthe 2006), and concepts such as happiness, health, illness, and mental disorder (Brülde 2000, 2006a, 2006b). Research on several of the conceptual issues has demonstrated how they are strongly connected to ethical problems related to health care policies and public health practices, in particular issues about what are the appropriate goals of medicine as a whole, or parts thereof, e.g. the goals of palliative care, psychotherapy, rehabilitation, or treatments of chronic illnesses. Normative theories about appropriate goals are necessary to come up with plausible grounds for diagnostic categories, outcome measures and policy guidelines in different areas. Some attempts...
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...Genetics Scott Cliff Post University Genetic engineering (GE) has been presented to the public as a way to improve the quality of our lives, enhance agriculture and advance our ability to fight genetic illnesses. The possibilities seem endless, but raise worries as well as optimism (Fricker, 2002). The Human Genome Project, conducted by the U.S. Department of Energy and the Department of Health and Human Services, undertook the task of mapping all human genes their chromosomes (Morse, 1998). This project contributed greatly to the potential for GE in humans, but in fact GE has already been used in agriculture. However, some biologists point out that we call “genetic engineering” has been accomplished for centuries via cross-breeding, and that GE is just a new way of accomplishing something already done in the past (Fricker, 2002). The risk with GE is that genes can be combined in ways never before possible, and with possibly unpredictable results. For a decade, we have had the capability to insert alien genes into target cells, thus changing the organism. This can be done with cells taken from a patient. After altering, they can be returned to the patient to achieve some medical goal (Anderson, 1990). The concern with GE is that it can have both anticipated and unanticipated effects (Fricker, 2002). Because of this, we should proceed cautiously and carefully, with many safeguards in place. Genetic engineering is largely uncharted territory and only hubris would allow...
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...of care by a reasonably prudent professional 3. breach causes damages that were foreseeable. 4. Negligence Theory: , Can negligence be criminal—US v Parks case Yes! If informed of an issue, should follow through and ensure action was taken (supermarket example) States’ Differing Public Policy on role of stakeholders in making a decision that is in the best interests of the company * Half of the states say the officers and directors can take into account stockholders and other stakeholders (employees, customers, supplies, communities). * Pennsylvania and Indiana allow officers to place the interests of stakeholders above stockholders Why most companies choose Delaware to incorporate Management friendly. Example: business judgement rule Drucker’s Aristotelian statement--aligning a company’s competencies with societal problem “Organizations have a responsibility to try to find an approach to basic social problems which fits their competence and which, indeed, makes the social problem into an opportunity for the organization.” Peter Drucker Aristotle’s Eudaimonia—”full flourishing” if one practiced virtues/excellence for the public good...
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