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Hepatitis A Research Paper

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Abstract Hepatitis A is a serious disease. It can be found in the liver. This disease was discovered by Steven M. Feinstone in 1973. The Hepatitis A virus is a small non-enveloped single-stranded RNA virus. This disease normally causes inflation in the liver. Histologic regression of both necroinflammation and fibrosis has been demonstrated in paired liver biopsy samples in SVR-achieving patients. The first description of hepatitis A is generally attributed to Hippocrates and outbreaks of hepatitis A has been recognized for centuries,affecting both military and civilian populations.Major geographical differences in endemicity of hepatitis A are closely related to hygienic and sanitary conditions and other indicators of the level of socioeconomic …show more content…
It was first discovered in 1973 by Steven M. Feinstone a nonenveloped, spherical, positive stranded RNA virus. HAV was an unidentified viral disease prior to this discovery. Hepatitis A is a disease caused by infection from the hepatitis A virus . Hepatitis A is called epidemic hepatitis, epidemic jaundice, infectious hepatitis, catarrhal jaundice, HA, and type A hepatitis in the past. These strains include hepatitis A, B, C, D or E. Virulence factors associated with HAV include viral agents that produce an immune response. These antibodies become present five to ten days after the initial infection. HAV is absorbed into the bloodstream from the small intestines and reaches the liver through portal circulation. HAV is classified to be in the genus of hepatovirus, and belongs to the picornavirus family. Due to the multiple possibilities of infection it is vital that HAV be singled out as the cause. A patient’s sera must be tested for the presence of specific antiviral antibodies to detect the presence of HAV. A positive test for anti-HAV means that the patient has either been exposed to HAV in the past, or is currently infected. The enzyme-linked immunosorbent assay test was developed to detect the HAV antibody. HAV can also be diagnosed through detection of the HAV antibody in the …show more content…
This disease is primarily spread by food or water from someone that is infected by this disease. It’s a bacterium. Hepatitis is one of the oldest diseases known to humankind by the World Health Organization. It was first discovered in 1973 by Steven M. Feinstone a nonenveloped, spherical, positive stranded RNA virus. The first description of hepatitis A is generally attributed to Hippocrates and outbreaks of hepatitis A has been recognized for centuries,affecting both military and civilian populations.The hepatitis The infection of hepatitis A is a worldwide infection.Hepatitis A affects about 50% of the people who live in the U.S.There is also acute hepatitis which causes a minor flu-like illness to fatal liver failure.The relative frequency of HAV as a cause of acute hepatitis has declined in Western societies, while in contrast, notification of individual cases has increased, primarily as a result of improved reporting and diagnostic techniques.Histologic regression of both necroinflammation and fibrosis has been demonstrated in paired liver biopsy samples in SVR-achieving patients. One way to protect yourself is always wash your hands thoroughly after using the restroom and when you come in contact with an infected person’s blood, stools, or other bodily fluids. Another way to protect yourself avoid unclean food or water. Avoid dairy products, and raw or undercooked meat and fish. Do not buy food from street

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