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Macrovascular Complications Of Hypertension

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Hypertension damages the arterial walls they either become hard and thick narrowing the lumen or the wall may dilate or tear blood supply to the affected areas is reduced which makes the body prone to ischemia and necrosis due to loss of adequate circulation (Hinkle & Cheever, 2014, p.862).
Hypertension is the complex interactions among factors that regulate cardiac input. The sympathetic nervous system can become over stimulated resulting in increased cardiac output and vasoconstriction. The renin angiotensin- aldosterone system controls sodium intake and overall volume, and affects the vasomotor tone of the RAAS. Chemical mediators of vasomotor tone and blood volume such as ANP factor affect vasomotor tone and sodium and water excretion, endothelin-1 is a potent vasoconstrictor (LeMone, 2015, p.969). …show more content…
Proinflammatory cytokines are released in the presence of hyperglycemia, which increases insulin resistance which leads to inflammatory damage of the endothelium (LeMone, 2015, p. 524).
Macrovascular complications of type II diabetes usually arise from Atherosclerosis which results in hypertension, coronary artery damage, cerebral and carotid artery damage, and peripheral arterial damage (also known as peripheral vascular disease) ( LeMone, 2015, p. 525). Due to patients’ history with uncontrolled type II diabetes. Hypertension, family history of CAD patient was placed on

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