The cell membrane is made up of the outer and inner cell membrane with a trilaminate structure, which enclose the pre nuclear cistern between them by parallel-going process. Darnell J et al (1990) From the one side huddled to the inner nuclear membrane surface and from the other side from the periphrical chromatin of a eukaryotic nucleus there is a high -protein lamination ( thickness 30-100 nm) out of filaments -which is called the nuclear lamina . Newport JW et al (1987) The lamina can be isolated biochemically, and remaining matrix has the same form and size like the treated cell and is only made out of lamina proteins which forms a stable fibular bonding polymer network . Lamina A, B1, B2 and C are those who built the lamina proteins. They belong to the family of the type 5 intermediate filaments. Intermediate filaments are structures built of proteins which increase the mechanic stability of a nucleus. A single monomer of the intermediate filaments is about 48 nm long and very thin. Type 5 is one of the six types of the intermediate filament (online last accessed 29/10/2010). The connection from the lamina with a cell membrane is achieved through lamina B according to Newport et al, because it has a special role when bonding with the membrane, while the other laminas connect to lamina B and transmit interaction between chromatin and the lamina. Dessev GN et al (1992) consider an indirect interaction between non lamina components of the nucleolus membrane and a lamina B receptor for possible. Pyrpasopoulou A et al (1996) The lamina, lamina- associating polypeptides and lamina B receptor connect to the DNA or interact with chromatin via the histones and thereby influence chromosome position in the cell. The lamina is responsible for the retention of the nuclear form and as the base frame for the chromatin adherence regarding to Newport et al. Goldberg M & Bosman