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Prefrontal Dichotomy

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The purpose of this study was to examine the “functional organization of the prefrontal cortex and how it is affected by learning to perform tasks that require working memory for spatial locations and features of stimuli” (Meyer, Lian, Stanford, & Constantinidis, 2011). To illustrate this hypothesis, research by Meyer, Lian, Stanford, and Constantinidis (2011) examined the results of working memory tasks in the context of two contrasting theoretical models of organization in the prefrontal cortex. One theoretical position, the domain-specific model, argues that the dorsal and ventral regions of the lateral prefrontal cortex are specialized for spatial and nonspatial representations of information, respectively; this is a dichotomy that parallels that of the dorsal and ventral visual streams (Meyer et al., 2011). Moreover, this model represents a content-based viewpoint, which argues that different areas of the prefrontal cortex are involved in different types of working memory based on domain (Owen, 1997). An alternative position, the integrative model, argues that the dorsal and ventral regions of the prefrontal cortex are shaped by the demands of cognitive tasks imposed on them by an external environment (Meyer et al., 2011). According to this position, this model represents a process-based viewpoint, which concerns itself with whether the information is maintained or manipulated.

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