...Causes of Leukemia Leukemia is cancer of the blood-forming tissues and it strikes all ages and both sexes. Leukemia is a term given to a group of malignant diseases of the bone marrow and lymphatic system. In a person with leukemia, the bone marrow makes abnormal white blood cells (Wong, 2007). The abnormal cells are leukemia cells, unlike normal blood cells; leukemia cells don't die when they should. They may crowd out normal white blood cells, red blood cells, and platelets. This makes it hard for normal blood cells to do their work (Wong, 2007). This can lead to serious problems such as anemia, bleeding, and infections. Leukemia cells can also spread to the lymph nodes or other organs and cause swelling or pain. This paper examines how leukemia is diagnosed, the main types of treatment of leukemia and possible causes of leukemia (Bhojwani, 2009). Diagnosis of Leukemia Leukemia may be acute or chronic. Acute leukemia gets worse very fast and will make a person feel sick right away. Chronic leukemia gets worse slowly and may not cause symptoms for years. Doctors typically find leukemia after a routine blood test, when a patient has symptoms that suggest leukemia. Symptoms may depend on what type of leukemia a person has, but common symptoms are fever and night sweats, headaches, bruising or bleeding easily, bone or joint pain, a swollen or painful belly from an enlarged spleen, swollen lymph nodes, feeling very tired or weak, losing weight and not feeling hungry. The acute types...
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...Sickle Cell Disease is an illness that affects people all across the globe. This paper will give a description of the sickness through the discussion of the causes, symptoms, and possible cures. Sickle Cell Disease (SCD) is a "group of inherited red blood cell disorders."(1) These disorders can have various afflictions, such as pain, damage and a low blood count--Sickle Cell Anemia. Sickle cell disease is the most common inherited blood disorder in the United States. Approximately 80,000 Americans have the disease. In the United States, sickle cell disease is most prevalent among African Americans. About one in 12 African Americans and about one in 100 Hispanic Americans carry the sickle cell trait, which means they are carriers of the disease. Sickle cell disease is caused by a mutation in the hemoglobin-Beta gene found on chromosome 11. Hemoglobin transports oxygen from the lungs to other parts of the body. Red blood cells with normal hemoglobin (hemoglobin-A) are smooth and round and glide through blood vessels. In people with sickle cell disease, abnormal hemoglobin molecules - hemoglobin S - stick to one another and form long, rod-like structures. These structures cause red blood cells to become stiff, assuming a sickle shape. Their shape causes these red blood cells to pile up, causing blockages and damaging vital organs and tissue. Sickle cells are destroyed rapidly in the bodies of people with the disease, causing anemia. This anemia is what gives the disease...
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...2011 Maria Corriveau Final Paper 12/5/2011 2011 Maria Corriveau Final Paper 12/5/2011 Autologous peripheral blood stem cell transplantation for acute myeloid leukemia: an innovate technique Autologous peripheral blood stem cell transplantation for acute myeloid leukemia: an innovate technique Autologous peripheral blood stem cell transplantation for acute myeloid leukemia: an innovate technique 1. Principle of the technique Bone marrow transplantation and peripheral blood stem cell transplantation are procedures that help to restore those stem cells that have been destroyed while going through radiation and/or chemotherapy. There are different types of transplantation: autologous, syngeneic, and allogeneic. Autologous transplantation is defined as the transplantation of owns stem cells. Syngeneic transplantation is when patients received stem cells from an identical twin. Lastly, allogeneic transplantation is when patients received stem cells from a sibling, or a parent, or other individuals not related to the patient as long compatibility is present. Autologous bone marrow transplantation is a technique that was developed for patients with acute myeloid leukemia (AML) as an alternative to allogeneic stem cell transplantation. However, this technique was not very successful. Autologous bone marrow transplantation has been associated with prolonged marrow aplasia resulting in toxicity and mortality. After the failure of this technique, researchers...
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...Stem Cell Research in Human Transplantation [Name of the Writer] [Name of the Institution] Abstract Skeletal Bone Marrow that is decimated by disease, chemo, or radioactive emission can be refurbished by utilizing stem cell transplants. For certain infectious ailments like leukemia, aplastic anemia, certain inherited body-fluid infections, and some infections of the immune cell, and the stem cells in the skeletal bone marrow do not effectively function the way that it is intended to function. The stem cell is subjected to immunity issues where the recipient body site does not accept the donor cells. This paper will look to enquire the benefits to following stem cell research in human transplantation. Stem Cell Research Introduction Unique functional cells such as for example, a red blood cell start out originally as unspecialized cells known as stem cells. These stem cells have the uncanny ability to keep separating through division and multiplying in culture to produce specialized cell for a specific bodily function. In the context of normal human development, they are best described for their diversity, adaptability and longevity. As the laws of biology dictate, a human being is formed when a sperm cell fertilizing a female egg cell to produce a zygote. The zygote is already specialized in the fact that it is on the way to the formation of a whole individual. Furthermore the zygote, also known as the fertilized egg is tot potent that simply...
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...Stem cell research is an extremely diverse subject. There are people who agree with it, and other’s who do not. Some people do not believe in it because of their religious beliefs, which is understandable. What they do not know though is how many diseases it can cure or how many lives it could save. The only type of stem cell research that is right is adult stem cell research, which is what we will be discussing in this paper. In no way shape or form is it right for someone to use embryonic stem cells. The only way that it is okay to use them is if you have already had a child and take them from the umbilical cord. But one should never abort a child just for something such as stem cells. Carry that baby full term and then use the cord to get...
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...Sickle cell anemia(SCD) is an inherited genetic disorder which causes the expression of defective hemoglobin on chromosome 11 resulting irregularly shaped red blood cells also known as “sickle cells” because they look like a sickle or are in a crescent shape. The normal red blood cells are round, smooth and deliver oxygen to cells throughout the body but a cluster of sickle shaped cells blocks the blood flow, causing painful attacks and sometimes stroke. Due to their different shape and chemistry, they are controlled by many free radical processes. This paper will talk about the frequency this disease, inheritance pattern, genetic changes, current research and/or efforts to develop vaccine, symptoms, diagnosis and treatment of sickle cell anemia....
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...* What Is a Blood Disorder? Bottom of Form Blood disorders are physical conditions that prevent the normal function of blood in the body. A disorder may involve factors that interfere with the production of the individual components found in the blood, such as hemoglobin or blood proteins. The nature of a blood disorder may also include situations where the blood does not coagulate properly, or the blood cells themselves are malformed or infected. There is a wide range of blood diseases known today. Anemia is one of the more common examples of a blood disorder. Sometimes referred to as tired blood, a person who is anemic is likely to have a lack of proteins and other elements in the blood. As a result, the blood cannot carry the needed nutrients to various parts of the body and the individual is likely to feel fatigued more often. Over time, anemia can also have a negative impact on the emotions, as the blood is unable to supply proper nutrition to the brain for the production of chemicals that help to maintain an even mood. Sickle cell anemia is one of the more serious types of anemic blood disorder. In addition to fatigue, a person suffering with this disorder is also likely to experience a great deal of pain. The pain may be localized in one part of the body or migrate to different areas throughout the course of the day. Ad Hemophilia is another relatively common blood disorder. Hemophiliacs suffer with a condition in which the blood lacks the normal ability to coagulate...
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...Stem cell research is a massive topic of discussion within many groups of people around the world. Whether it is right or wrong is the question, however in stem cell research there is no such thing as wrong. People are usually against stem cell research because they are also against abortion and there are horror stories of the experiences patients and pathologists have had with abortion. People believe that stem cell research gets embryonic stem cells from an abortion clinic what an abortion clinic does with the fetuses is either send them to a pathology facility or they just throw them away in the trash. Stem cell research does not use aborted fetuses or embryos for collection of embryonic stem cells. The People against the idea of Embryonic...
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...1 Personal Impact Paper on Sickle Cell Disease Glenda Kessen NUR427 9/8/14 Amy Highland 2 Sickles Cell Anemia is a chronic, serious red blood cell disorder that is lifelong. "It is the most common genetic disease in the United States." (Guyatt, GH 2007). Sickle Cell Disease (SCD) is inherited and results in a decrease of the ability of red blood cells to carry much-needed oxygen through the body. The cells become clogged, due to their crescent shape, which keeps them from delivering oxygen. This can cause unbearable pain, damage to the body organs, and even death. The frequency of the pain episodes can range from several a year to multiple times a day. SCD is caused by hemoglobin S, which is an abnormal type of hemoglobin. When the cells are exposed to low oxygen levels, the Hemoglobin S changes the shape of the red blood cells. Red blood cells are made of marrow that is located inside the large bones of the body. The bone marrow is constantly making new red blood cells to replace the old cells. The life of the normal red blood cell life is about 120 days. Their purpose is to carry oxygen and remove the carbon dioxide, which is a waste product, from the body. Sickle-shaped cells die about ten to twenty days that prevents the bone marrow from making new red blood cells. Ethnicity plays a part in SCD, with African Americans more likely to be affected. Both parents are carriers of the sickle cell trait which is passed on to the child. The child will inherit...
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...[pic] Term paper Stem cell therapy Irfan manzoor. Roll no: RP7002B22. Reg. no: 11000225. Course: Bsc. Biotech 1. Lovely professional university Contents 1. Stem cells and properties. 2-3 2. Stem cell therapy. 5-12 3. Stem cell use in animals 13-15 4. Recent researches in stem cell therapy 16-19 5. Conclusion 21 6. Bibliography 22 Stem cells Stem cells are cells found in all multi cellular organisms. They are characterized by the ability to renew themselves through mitotic cell division and differentiate into a diverse range of specialized cell types. Research in the stem cell field grew out of findings by Ernest A. McCulloch and James E. Till at the University of Toronto in the 1960s. The two broad types of mammalian stem cells are: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in adult...
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...Sickle Cell Disorder Research Paper Sickle cell anemia is a disease passed down through families in which red blood cells form an abnormal sickle or crescent shape. Red blood cells carry oxygen to the body and are normally shaped like a disc. Sickle cell disease refers to a group of inherited red blood cell disorders. It is the most common genetic disease in the U.S. An estimated 70,000-80,000 Americans have sickle cell disease. Normal red blood cells are round like doughnuts, and they move through small blood tubes in the body to deliver oxygen. Sickle red blood cells become hard, sticky and shaped like sickles used to cut wheat. When these hard and pointed red cells go through the small blood tube, they clog the flow and break apart. This can cause pain, damage and a low blood count, or anemia. What is sickle cell trait? A person with the sickle cell trait does not have (and will never have) sickle cell disease. However, the presence of the trait may impact his/her children How do you get sickle cell disease? Sickle cell disease is not contagious; you cannot "catch" it. You inherit it from your parents. If, for example, one parent has normal hemoglobin ( type AA) and the second parent has abnormal hemoglobin ( type AS, or the sickle cell "trait"), there is a 50% chance that each child will have the sickle cell trait, but they will not have sickle cell disease ( type SS). The three most common forms of the disease in the United States are: 1. Hemoglobin...
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...the geriatric population is estimated at 5-15%. Although the prevalence of anemia is greater in women than men aged less than 75, by age 75, male prevalence surpasses female prevalence by about 5%. Anemia can be mild, moderate, or severe enough to lead to life-threatening complications. More than 400 different types of anemia have been identified, many of which are rare. Iron deficiency anemia The onset of iron deficiency anemia is gradual and, at first, there may not be any symptoms. The deficiency begins when the body loses more iron than it derives from food and other sources. Because depleted iron stores cannot meet the red blood cell's needs, fewer red blood cells develop. In this early stage of anemia, the red blood cells look normal but they are reduced in number. Then the body tries to compensate for the iron deficiency by producing more red blood cells, which are characteristically small in size. Symptoms of anemia develop at this stage. Folic acid deficiency anemia Folic acid anemia is especially common in infants and teenagers. Although this condition usually results from a dietary deficiency, it is sometimes due to inability...
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...are derived from plants that have been used by traditional medical practitioners (Cragg and Newman, 2005). It is a fact that traditional systems of medicine have become a topic of global importance. African countries are at a stage where traditional medicine is considered more for its capacity to generate other medicine than for its own sake. In many cases research undertakings and the commercial use stemming from that research have always relied on information provided by the local communities and, in many instances, have hardly benefited from the research results (Rukangira, 2004) . In Africa, traditional healers and remedies made from plants play an important role in the health of millions of people. (Rukangira, 2004). Typically, studies on the medicinal plants such as Alstonia boonei have focused on the bioactivity of its chemical constituents, ethnobotany, pharmacology, and taxonomy. However, a comprehensive or systematic review on the plant is lacking. Furthermore, in much of the older literature concerning West Africa, the name Alstonia congensis has been erroneously used for Alstonia boonei. Consequently, this paper examined the effect of aqueous bark extracts of Alstonia boonei on the haematological parameters of male wistar abino rats. 1.2 LITERATURE REVIEW 1.2.1 Classification Alstonia comprises about 40 species and has a pantropical distribution. There are about twelve species of the genus Alstonia. Alstonia boonei De Wild belongs to the family Apocynaceae. The...
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...ABSTRACT Stem cells have offered much hope by promising to greatly extend the numbers and range of patients who could benefit from transplants, and to provide cell replacement therapy to treat debilitating diseases such as diabetes, Parkinson's and Huntington's disease. The issue of stem cell research is politically charged, prompting biologists to begin engaging in ethical debates, Stem cell research offers great promise for understanding basic mechanisms of human development and differentiation, as well as the hope for new treatments. However, human stem cell research also raises sharp ethical and political controversies. This paper will discuss the types of stem cells as well as some of the controversies involved in stem cell research. Introduction According to Wikipedia, stem cell can be defined as “biological cells found in all multicellular organisms, that can divide (through mitosis) and differentiate into diverse specialized cell types and can self-renew to produce more stem cells.” A stem cell could be regarded as one of the basic building blocks of the human body. Stem cells are important because they have the ability to become different cell types, and scientists are working on developing ways to use stem cells to repair or regenerate damaged organs or tissues. This could lead to therapies for a whole range of conditions such as heart disease, diabetes, Parkinson's disease or Alzheimer's, although at present it is impossible to tell whether this will happen...
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...involving impaired production, impaired function, or abnormal destruction of blood cells are likely to have wide-reaching effects on the patient's health and wellness (Ignatavicius & Workman, 2010, p. 876). This is especially clear when examining cancers of the hematologic system, including multiple myeloma. A cancer of certain white blood cells in the bone marrow known as plasma cells, “myeloma” refers to a tumor of the bone marrow, and “multiple” refers to more than one area of the bone marrow being affected (Mangan, 2006, p. 64hn1). Because the disease is incurable, and because only 30 percent of patients survive longer than five years after diagnosis, living with multiple myeloma can be difficult for patients and their families (Mangan, 2006, p. 64hn1). As health care providers on the front lines of patient care, nurses must be aware of the multi-system manifestations of multiple myeloma, be able to make the assessments needed to identify and prevent complications related to the disease and its treatment regimen, and be ready to provide patients and their families with knowledge and support. In this paper, the author will first provide a full description of multiple myeloma, including etiology and risk factors, pathophysiology, diagnostic tests, and treatment. This accomplished, the author will apply the stages of the nursing process to nursing care...
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