...decade, mobile phone use increased to almost 100% prevalence in many countries of the world. Evidence for potential health hazards accumulated in parallel by epidemiologic investigations has raised controversies about the appropriate interpretation and the degree of bias and confounding responsible for reduced or increased risk estimates. data sources: Overall, I identified 33 epidemiologic studies in the peer-reviewed literature, most of which (25) were about brain tumors. Two groups have collected data for ≥ 10 years of mobile phone use: Hardell and colleagues from Sweden and the Interphone group, an international consortium from 13 countries coordinated by the International Agency for Research on Cancer. data synthesis: Combined odds ratios (95% confidence intervals) from these studies for glioma, acoustic neuroma, and meningioma were 1.5 (1.2–1.8); 1.3 (0.95–1.9); and 1.1 (0.8–1.4), respectively. conclusions: Methodologic considerations revealed that three important conditions for epidemiologic studies to detect an increased risk are not met: a) no evidence-based exposure metric is available; b) the observed duration of mobile phone use is generally still too low; c) no evidence-based selection of end points among the grossly different types of neoplasias is possible because of lack of etiologic hypotheses. Concerning risk estimates, selection bias, misclassification bias, and effects of the disease on mobile phone use could have reduced estimates, and recall bias may have led...
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...and 59% for stroke and heart disease respectively while it has been static for cancer with no decrease in death rates inspite of extensive research and treatment efforts. This suggests that something is wrong about cancer treatment. The term “Five year survival rate” hides within it our sad story of not being able to find a permanent cure to cancer. Chemotherapy, radiotherapy, surgery are not curative but symptomatic therapies merely extending our lives. Our scientists inspite of doing researches involving billions of money and publishing an amazing 1.5 million papers have not found a cure to cancer. We have been only able to increase the five year survival rates from 48.75 % in 1975 to 69% in 2007, pointing to us that there is something wrong. Radiotherapy and chemotherapy increases risk of leukemias and solid tumors, targeted therapy to melanoma and stem cell transplant can result in second cancers. The irony of cancer treatment causing cancers and the unending list of severe side effects from vomiting, alopecia to infertility and immunocompromised state gives a sickening feeling about the cancer management we are following. 90% of the time the cause of death in cancer is metastases. We don’t have any weaponry to attack them except palliative pain treatment. Its not even in our priority list with only less than 0.5% of research projects on metastases. Not targeting the biggest monster i.e. metastases makes me feel wrong about our current cancer management. Running...
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...EFSA Scientific Report (2009) 231, 1-107 SCIENTIFIC COOPERATION AND ASSISTANCE SCIENTIFIC REPORT OF EFSA Review of the potential health impact of β-casomorphins and related peptides 1 Report of the DATEX Working Group on β-casomorphins (Question N° EFSA-Q-2008-379) Issued on 29 January 2009 WORKING GROUP MEMBERS Ivano De Noni, Richard J. FitzGerald, Hannu J. T. Korhonen, Yves Le Roux, Chris T. Livesey, Inga Thorsdottir, Daniel Tomé, Renger Witkamp. 1 For citation purposes: Scientific Report of EFSA prepared by a DATEX Working Group on the potential health impact of β-casomorphins and related peptides. EFSA Scientific Report (2009) 231, 1-107 © European Food Safety Authority, 2009 Review of the potential health impact of β-casomorphins and related peptides SUMMARY Proteins are a very diverse family of large organic compounds involved in many important biological processes. Following their enzymatic hydrolysis during food processing or digestion, proteins may release fragments from their primary amino acid sequence. These fragments are called peptides, and many of them are known to be physiologically active. The possible beneficial effects of bioactive peptides have attracted increasing interest in recent years. On the other hand, there are also reports suggesting that some food-derived peptides might adversely affect human health. Among these, β-casomorphin-7 (BCM7), a peptide sequence present in the milk protein β-casein, has been suggested to...
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