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The Selective One

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Submitted By jamhoward
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What’s one of the most common drugs in history that is used for many different reasons? Aspirin. Approximately 35000 metric tons are produced and consumed every year. Acetylsalicylic acid also known as aspirin is often used to relieve minor aches and pains as an antipyretic to reduce fever, and as an anti-lamasery medication. Many people don’t know what aspirin is but only what it does for their particular needs. Aspirin is a white crystalline substance made of carbon, hydrogen, and oxygen. It is used in the treatment of rheumatic fever, headaches, neuralgia, colds, and arthritis; reduce temperature and pain. The formula for aspirin is C9H8O4. Aspirin's scientific name is acetylsalicylic acid. The main ingredient in ASA is salicylic acid. Aspirin is derived from a chemical extracted from willow bark: Salicylate Acid. Salicylate Acid has a long history of uses. During Medieval times herbalists used it for its palliative properties. This ingredient grows in small roots, leaves, flowers and fruits on plants. The willow leaf was used as herbal medicine by the ancient Greeks during childbirth to ease labor pains. There is also documentation of the first proper scientific study of the herbal remedy in year 1763. Dried willow bark was used by Reverend Edward Stone of Chipping Norton near Oxford on 50 parishioners suffering from rheumatic fever. He then recorded the benefits it had. It wasn't until year 1823 that salicin was extracted from willow and formally named. A German chemist named Felix Hoffmann set out to find a drug that would ease his father's arthritis without causing severe stomach irritation. His father’s stomach irritation came from sodium salicylate. Salicylate was the standard anti-arthritis treatment of the time. Hoffmann figured that the acidity of the salicylate made it hard on the stomach's lining. He then began looking for a less acidic formulation.

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