Unit 4 Case Study 2: Skin Cancer Skin cancer is a rather harsh reality for many people that love soaking up the sun, however genetics and gene mutation may be playing a larger role in the development of carcinomas. Almost everyone has experienced a sunburn from staying out at the beach for too long, or not reapplying the appropriate amount of sunscreen. The damage that UVA and UVB rays can do to the integumentary system in a short period of time can cause life changing effects. Genetic mutations
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Michaela P. Capulong SC435-02: Genetics November 24, 2015 Unit 3 Final Project Breast Cancer Breast cancer is one of the leading causes of cancer among women and only affect one percent of men. There are multiple risk factors for breast cancer this include genetic abnormalities, unhealthy lifestyle, and environmental. The BRCA1 and BRCA2 are tumor-suppressor genes. The mutation and abnormalities of these genes could increase the people risk of breast cancer and also ovarian cancer. Cancer develops
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Introduction Aperts syndrome is a developmental disorder of genetic origin. It is caused by a mutation of chromosome ten and is common in older dads. The disorder is due to many different reasons and is treated accordingly depending on the various symptoms. This syndrome is characterized by iconic signs and symptoms. Aperts also affects many people in many ways such as physically and intellectually. Aperts syndrome is preventable but only by abstinence. Pathophysiology, Incidence, and Diagnosis
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The Curious Case of Benjamin Button “The Curious Case of Benjamin Button” is notable not just for having the least likely title of a major Hollywood hit since “Forest Gump.” It also features images you don’t see every day: Using sophisticated makeup, long segments of the tale show superstar Brad Pitt’s face, aged beyond his years. He looks so different that a confused Angelina would kick him out of their kids’ nursery. His wrinkled countenance is then seamlessly computer grafted onto a diminutive
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Introduction Ultraviolet (UV) radiation reaching the Earth’s surface has increased significantly over the last 20 years from increased ozone depletion. UV radiation is a component of sunlight that is divided into three parts: UVA (320-400nm), UV-B (280-320nm) and UVC (less than 280nm) [25]. Wavelength determines the transmission of UV radiation through the Earth’s atmosphere. UVC is completely absorbed by the atmospheric gases; UV-B radiation is absorbed by ozone layer and only a small amount reaches
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p53 is considered to be an important and useful protein that plays a key role in cancer and tumor suppression. Many of the pathways in which p53 is utilized usually are apoptosis, cell deterioration also known as senescence, cell cycle arrest or DNA repair (Riley et. al, 2008). P53 also plays a role in glucose metabolism as a regulator of glycolytic and oxidative phosphorylation through positive and negative regulation of certain genes and the proteins that they encode for (Madan et. al, 2011). Usually
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Biology Article Introduction to Biology, SCI 115 Biology Article In an exclusive interview with USA TODAY, Angelia Joie, one of Hollywood’s supernova leading ladies revealed that she has a double mastectomy after learning that she carries a mutated version of the gen BRCA1 and had a high risk of breast cancer. On the front page of the article, Jolie was praised for her bravery, beauty, and openness announcing her possible operation and why she had it in the New York Times, (USA TODAY
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Defining the Methyl-Specific Recognition of BRCT Domain Proteins An important tumor suppressor for preventing carcinogenic mutations with direct roles in DNA repair and transcriptional regulation is a gene known as Breast cancer gene 1(BRCA). These genes have several domains. These domains have important roles in tumor suppression as several pathogenic mutations have been mapped to BRCA1’s C terminal (BRCT). However, there is an emerging paradigm that BRCT domains have binding sites capable of
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Hutchinson- Gilford Progeria syndrome(HGPS) which is more commonly known as Progeria is an extremely rare genetic disorder in which the child ages rapidly. Progeria must be diagnosed and is a lifelong illness. Progeria was first detected by Dr. Jonathan Hutchinson in 1886, then by Dr. Hastings Gilford in 1897. This is evidently where the disorder got its name. Progeria is caused by a genetic mutation that occurs before birth. The mutation occurs in the LMNA gene. The LMNA gene is responsible for
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