...Kauer,1 Johannes Rainer,3 Reinhard Kofler,3 Andrew Hall,4 Markus Metzler,5 Luder Hinrich Meyer,6 Claus Meyer,7 ¨ Jochen Harbott,8 Rolf Marschalek,7 Sabine Strehl,1 Oskar A. Haas,2 and Renate Panzer-Grumayer1,2 ¨ Cancer Research Institute, St Anna Kinderkrebsforschung, Vienna, Austria; 2St Anna Kinderspital, Vienna, Austria; 3Tyrolean Cancer Research Institute and Biocenter - Division Molecular Pathophysiology, Innsbruck Medical University, Innsbruck, Austria; 4Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom; 5Department of Pediatrics, University of Erlangen-Nuremberg, Erlangen, Germany; 6Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany; 7Institute of Pharmacological Biology/DCAL, Goethe-University, Frankfurt, Germany; and 8Onkogenetic Laboratory, Department of Pediatric Hematology/Oncology, Justus-Liebig-University, Gießen, Germany 1Children’s Approximately 25% of childhood acute lymphoblastic leukemias carry the ETV6/RUNX1 fusion gene. Despite their excellent initial treatment response, up to 20% of patients relapse. To gain insight into the relapse mechanisms, we analyzed single nucleotide polymorphism arrays for DNA copy number aberrations (CNAs) in 18 matched diagnosis and relapse leukemias. CNAs were more abundant at relapse than at diagnosis (mean 12.5 vs 7.5 per case; P .01) with 5.3 shared on average. Their patterns revealed a direct clonal relationship with exclusively new ab- errations at relapse...
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...* What Is a Blood Disorder? Bottom of Form Blood disorders are physical conditions that prevent the normal function of blood in the body. A disorder may involve factors that interfere with the production of the individual components found in the blood, such as hemoglobin or blood proteins. The nature of a blood disorder may also include situations where the blood does not coagulate properly, or the blood cells themselves are malformed or infected. There is a wide range of blood diseases known today. Anemia is one of the more common examples of a blood disorder. Sometimes referred to as tired blood, a person who is anemic is likely to have a lack of proteins and other elements in the blood. As a result, the blood cannot carry the needed nutrients to various parts of the body and the individual is likely to feel fatigued more often. Over time, anemia can also have a negative impact on the emotions, as the blood is unable to supply proper nutrition to the brain for the production of chemicals that help to maintain an even mood. Sickle cell anemia is one of the more serious types of anemic blood disorder. In addition to fatigue, a person suffering with this disorder is also likely to experience a great deal of pain. The pain may be localized in one part of the body or migrate to different areas throughout the course of the day. Ad Hemophilia is another relatively common blood disorder. Hemophiliacs suffer with a condition in which the blood lacks the normal ability to coagulate...
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...| 2012 | | Leukemia and Lymphoma Society Tawanda Bryant | [Leukemia and Lymphoma Society] | The Leukemia & Lymphoma Society (LLS) is: Cure leukemia, lymphoma, Hodgkin’s disease and myeloma, and improves the quality of life of patients and their families. Providing free information and support services, Leukemia and Lymphoma funds lifesaving blood cancer research around the world. | LEUKEMIA & LYMPHOMA SOCIETY TAWANDA BRYANT 11410 COUNTY ROAD 20 BOLIGEE, AL 35443 (205) 336-9851 tbryant3030@yahoo.com LEADERSHIP and ORGANIZATIONAL MAR12 SEC AA March 9, 2012 INSTRUCTOR: SHAROLYN HERGOTT LEUKEMIA & LYMPHOMA SOCIETY I have picked this organization because my best friend passed away last year with leukemia and I wanted to find out more on this disease and what I can do to help. Been passionate and concern about not only her health but the health of her kids, my research will show why it is important to me as well as others. Having a passion for helping other in any way I can is what I am going for. I also like the face that I can somewhat relate to their illness and pain they endure within their life. I would love to find a quicker cure for these diseases, but I know others are working on something better. Having someone close to you with any type of disease, not just leukemia or lymphoma is hard to take in and understand. Having the ability to communicate, have critical thinking, collaboration, and the ability to problem solve is what I aim...
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...Running Head: Research Critique Part 1 1 Research Critique Part 1 CLABSI in the Pediatric Oncology Population Cathy Frederick Grand Canyon University NRS-433V Introduction to Nursing Research October 11, 2015 Research Critique Part 1 2 Purpose of the Research This paper will perform a research critique on a qualitative research study published in the Infection Control and Hospital Epidemiology, March 2013, Vol. 34, No.3. The study was presented with contributions from multiple individuals, Dr. A. Gaur, Dr. D, Bundy, C. Gao, PhD, Dr. E. Werner, Dr. A. Billett, Dr. J. Hord, Dr. J. Siegel, Dr. D. Dickens, C. Winkle, RN., and Dr. M. Miller. The research was to identify the host and organism characteristics of the hospital-acquired condition, central line-associated bloodstream infections (CLABSIs) in pediatric hematology/oncology patients. Problem Statement CLABSIs increase the risk for increased mortality and morbidity, extended hospital stays, and raises the overall cost of healthcare. Children’s Hospital Association Hematology-Oncology Quality Transformation Collaborative Project (CHAHQTCP), was a qualitative research project that began on November 1, 2009 and ended July 31, 2011. This project was initiated to identify the contributing factors to blood stream infections (BSI) in pediatric hematology patients. The goal of this research was to reduce CLABSIs by 50%. To be included, the CLABSI needed occur 48 hours after being hospitalized or...
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...Accounting for Not-for-Profit Organizations- St. Jude’s Children’s Research Hospital Tina Crawn Saint Leo University Accounting for Not-for-Profit Organizations- St. Jude’s Children’s Research Not-for-profit organizations are distinguished by characteristics to include receiving contributions of significant amounts of resources from resource providers who do not expect monetary benefits in return, operating for purposes other than to provide services or goods at a profit, and lack defined ownership interest that can be sold, transferred or redeemed. The Financial Accounting Standards Board is also responsible for overseeing not-for-profit organizations and accomplishes this by providing the Accounting Standards Codification or ASC. Not-for-profit organizations account for their revenues, expenses, assets, and liabilities on the full accrual basis of accounting. The financial statements are to provide information that meets the common interests of donors, members, creditors and other resource providers. (Ives, Patton, & Patton, 438). The financial statements required for NFPO include a statement of financial position, a statement of activities, and a statement of cash flows. Revenues, expenses, and investments are all received with certain classifications imposed on them. St. Jude’s Children’s research hospital is a not-for-profit organization founded by entertainer Danny Thomas and opened on February 4, 1962. St. Jude is supported primarily by donations raised...
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...Dim, flickering room lights, on at odd hours. The sound of powerful taps on a screen. Bleary eyes scanning the screen, rapid fusion of disparate information, brain whirring in a consistent, cyclic process. These actions form the substance of research; the substance of my identity. I was diagnosed with hyperactive and inattentive ADHD as a child, resulting in unfocused daydreaming, mental and physical restlessness, isolation in test rooms and being singled out in classrooms. Severe ADHD was an enormous burden for a child to experience and dare to succeed with, especially when nobody other than my parents, and my cousin Ha, truly understood me. While other children constructed life in coloring books and playgrounds, I used paper, markers, and my imagination to shape North Atlantic Coasts. Spending hours searching up everything from the strength of Typhoon Tip to the event horizon of black holes – books and research became the only devices that could quell the uncontrollable energy inside....
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...Mobile Telecommunications and Health Review of the current scientific research in view of precautionary health protection April 2000 ECOLOG-Institut Translated by Andrea Klein Mobile Telecommunications and Health Review of the Current Scientific Research in view of Precautionary Health Protection Commissioned by T‐Mobil DeTeMobil Deutsche Telekom MobilNet GmbH Authors Dr Kerstin Hennies Dr H.‐Peter Neitzke Dr Hartmut Voigt With the support of Dr Gisa‐Kahle Anders ECOLOG‐Institut für sozial‐ökologische Forschung und Bildung gGmbH Nieschlagstrasse 26 30449 Hannover Tel. 0511‐92456‐46 Fax 0511‐92456‐48 Email mailbox@ecolog‐institut.de Hannover, April 2000 Contents 1 1 1.1 1.2 2 Introduction 1 3 New Technologies and Precautionary Health Protection Terms of Reference and Structure of the Review 5 2.1 2.2 3 Collating and Interpreting the Scientific Data (Methodology) 5 5 Primary Reciprocal Effects between High Frequency Electromagnetic Fields and Biological Systems (Biophysical and Biochemical Processes) 3.1 3.2 3.3 3.4 3.5 4 Thermal Effects 3.1.1 Effects of Homogenous Warming 3.1.2 Microthermal Effects Direct Field Effects 3.2.1 Effects from the Electrical Component of the Electromagnetic Field 3.2.2 Effects from the Magnetic Component of the Electromagnetic Field ...
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...THE 2015 STATE OF THE NATION ADDRESS TECHNICAL REPORT Prepared by: The Office of the President of the Philippines TABLE OF CONTENTS TRANSPARENT, ACCOUNTABLE, AND PARTICIPATORY GOVERNANCE 1. Institutionalized Public Accountability .............................................................. 1 2. Upheld Transparency and Citizen Engagement in Government .................... 11 RAPID, INCLUSIVE, AND SUSTAINED ECONOMIC GROWTH 1. Sustained Strong and Broad-Based Economic Growth ................................. 14 2. Increased Opportunities for Employment and Economic Activity .................. 24 POVERTY REDUCTION AND EMPOWERMENT OF THE POOR AND VULNERABLE 1. Invested in the Filipino Workforce for Decent and Productive Work .............. 44 2. Sustained Equitable Access to Affordable and Quality Health Care .............. 50 3. Empowered the Poor and Marginalized towards Self-Reliance ..................... 56 JUST AND LASTING PEACE AND THE RULE OF LAW 1. Protected our National Territory and Boundaries........................................... 61 2. Ensured Public Order and Safety .................................................................. 64 3. Pursued Efforts for Peace and Development in Mindanao ............................ 68 4. Advanced and Protected Human Rights ........................................................ 71 5. Reformed the Justice Sector ......................................................................... 76 INTEGRITY...
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