Awad Awad
Prof. Robert Lawrence
English 1020 sec 005
27 Oct. 2014
Annotated Bibliography: Homochirality and life
Breslow, Ronald, and Zhan-Ling Cheng. "On The Origin of Terrestrial Homochirality for Nucleosides and Amino Acids." Proceedings of the National Academy of Sciences of the United States 23 (2009): 9144. Academic OneFile. Web. 9 Oct. 2014. The author argues that in the early years of our planet, the possibility of DNA, RNA, and Amino Acids emergency spontaneous generation had been proven by many experiments. However, Dr. Breslow states the fact that the only condition is to have a consistency of sugar backbone as D configuration of enantiomers to make the building blocks of life-Amino Acids-. Also, he claims that many meteorites, …show more content…
"Amino Acid Homochirality May Be Linked To the Origin of Phosphate-Based Life." Journal of Molecular Evolution 70.6 (2010): 572-582. Academic Search Premier. Web. 10 Oct. 2014. The authors argues that phosphorylation- is the addition of a phosphate (PO43−) group to a protein or other organic molecule- must have been one of the most important events in prebiotic evolution on earth because the team talks about the emergence of phosphoryl amino acid 50-nucleosides having a P–N bond is described as a model of the origin of amino acid homochirality They debate that it’s proposed that the intramolecular interaction between the nucleotide base and the amino acid side-chain influences the stability of particular amino acid 50-nucleotides, and the interaction also selects for the chirality of amino acids and differences between L- and D-conformation energies lead to the dominance of D configuration. They argue that the chiral selection of the earliest amino acids for L-enantiomers seems to be determined by a clear stereo-chemical/ physicochemical relationship. Therefore, amino acids developed from the earliest amino acids, the team deduced that the chirality of these late amino acids was inherited from that of the early amino acids. The three authors are scholars who study the chemical structures of Amino Acids and their relation to origin of life on Earth. The article contains tables and information to back their theory however they do not provide undoubtable …show more content…
"The Origin of Life - A Review of Facts and Speculations." Trends in Biochemical Sciences 12 (1998): 491. Academic OneFile. Web. 18 Oct. 2014. in the article, The author explores the two common theories about the origin of life. The first theory is that life came from space and started to adapt and grow in the earth’s atmosphere. The second theory is that life started in the hot vents of volcanos underwater. The article provides multiple evidence to support self-organization of early molecules such as the RNA. The author mentions evidences to support some of these speculations however he does not have a decisive conclusion for origin of life. Leslie E. Orgel is a biochemist whose studies of early life on primitive Earth helped lead to the formation of a now widely accepted theory about the development of DNA. He is also an Oxford University graduate and a very respected in the field of