...Introduction Stents were first developed in the late 1970s out of a need to keep coronary arteries open after balloon angioplasty (Cohen, 2006). Balloon angioplasty can weaken the arteries, sometimes causing them to collapse within a few days (Cohen, 2006). At that time, the only treatment available was emergency bypass graft surgery (Cohen, 2006). Further, angioplasty was causing restenosis in almost one-third of all patients (Cohen, 2006). Bare metal stents were developed in the mid 1980s out of a need to prevent or lower the incidences of restenosis due to angioplasty. While bare metal stents solved the problem of artery closure during the hospital stay, restenosis continued to occur in patients who received bare metal stents. In one-fourth of all cases, the stent experienced reblocking at around six months and had to be reimplanted (Cohen, 2006). Drug eluting stents were next developed in the hope that the pharmaceutical would prevent restenosis. Drug eluting stents have the same structure as a bare metal stent but are coated with a pharmaceutical. The pharmaceutical can also be contained within a thin polymer on the scaffolding of the stent to slow the release (Cohen, 2006). Drug eluting stents, in comparison to bare metal stents, decrease the risk of restenosis. However, drug elucting stents may increase the risk of stent thrombosis. Still searching for a solution that would reduce the risk of restenosis and stent thrombosis, a few companies are developing...
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