...article selected for this paper is “A study into the potential role of Survivin localisation in resistance to drug-induced apoptosis” written by Helen Angell. The paper is about the role of an anti-apoptotic factor from the class of caspases. The subcellular localisation of surviving can play important role in the therapy of breast cancer. Cancer is an abnormal process in which the cellular apoptosis is inhibited. Survivin is a protein known to regulate cell division and apoptosis. Chemotherapy in cancer patients in targeted to induce apoptosis. Surviving has been known to be localised in the cytoplasm and nucleus of the cells. The main therapeutic role of Survivin comes from the fact that the sensitivity of the breast cancer cells to chemotherapy is increased in its presence within the nucleus. Description of the methods and techniques used Various methods have been used by the author. All lab-based methods are used for the determination of localisation and presence of the protein in the cell. • The fourth method used is tissue culture, for the purpose of over expression the protein in the selected cells. • Second method subcellular fractionation was done for the separation of the cellular components. • Immunoblotting was chosen, as it is important for the identification of proteins based on their masses or weights (Hatano, 2010). • The main aim of the paper is to analyse the roles of Survivin as an important prognostic factor in the breast...
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...Social Studies School Based Assessment Social Studies School Based Assessment Subject: Social Studies School: St. George’s College Candidate Number: Territory: Jamaica Teacher: Mrs. Oliver Year: 2015 Title: An investigation into the role elders play in preventing drugs abuse among teenagers in the community of Pembroke Hall. Title: An investigation into the role elders play in preventing drugs abuse among teenagers in the community of Pembroke Hall. ACKNOWLEDGEMENT Firstly, I would like to give thanks to God almighty who gave me the strength and knowledge to be able to complete this project. For the advice given towards the completion of this project I would like to give special thanks to my parents, Orville Reid and Marva Perkins, for their continued guidance and help in this project and for providing me with the tools needed. Special thanks must also be given to my brothers, Scott Reid and Sean Reid, for providing me with the books needed to assist me in gathering the information for this project. I would also like to thank my teacher of Social Studies, Mrs. Oliver, for valuable time on giving assistance when needed and also assisting and guiding me of the right way of completing this project. Lastly, I would like to give special thanks to the members of the community of Pembroke Hall for their cooperation and support in answering the questionnaires. TABLE OF CONTENTS Topic Page Number...
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...Drugs: Teen Drug Addiction Kimberly Henderson COM 172 April 9, 2015 Beverly Woods Teen drug addiction is a very serious psychological and physical problem that involves many contributing factors abuse, divorce, peer pressure and physical issues, although there are many but limited recovery centers for teens. Even though we educate many teens still fall into the unfortunate lifestyle of drug addiction. Undeniably, no person ever says I want to be a drug addict. In today’s society teens are experiencing more stress from family, friends and school than ever before. “Divorce is common factor in teen drug addiction the parents may not accept or believe it but they play a crucial part in their teen’s lives in how they approach their child with family issues. A divorce can damage a teen severely depending on the age and gender”. (Temke, 2006p.2). Also abuse maybe an effect on a teenager. If a teen is being mentally, physically and sexually abused they will find ways to blame themselves for the abuse by using drugs to cover the pain. Friends who are using drugs will encourage them to try drugs to take the edge off,” saying it’s cool , you want become addicted, it helped me get through my problems.” Another is failing grades in school. Many may not see this but it’s considered to be a lack of confidence. Since parents today play a major role in their teenager education but can also add on stress from overloading their teenager with too many demands to be what they...
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... biological and chemical actions of drugs (Bryant & Knights, 2011). In the practice of medicine, drugs are used to diagnose, treat or prevent disease so for the registered nurse in a clinical setting, the knowledge of pharmacology plays a huge importance in their role of medication administration. Pharmacology knowledge allows the nurse to carry out safe medication administration, monitor medication actions, educate patients, and act legally and ethically within the pharmacological parameters. This knowledge is also vital for the nurse practititioner in their role of nurse prescribing. Pharmacology plays a huge part in these roles for the nurse. This essay below will elaborate on the importance of pharmacology for the five reasons of safe medication administration, monitoring of medication actions, patient education, legal and ethical aspects of pharmacology and the nurse practitioner. Firstly, safe medication administration. To administer drugs safely it is the nurse’s responsibility to have knowledge of the prescribed medications as well as their therapeutic and non therapeutic effects. Knowledge of the medications include, knowing its approved drug name and classification, correct dose and route of administration. A medication may have as many as three different names- a chemical name, a generic (proprietary) name and a trade name (Crisp & Taylor, 2011). A chemical name refers to the chemical makeup of a drug, a generic name is the drug name listed in official publications...
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...young men who grew up with single parent. Both showed intelligence early in life. Both also had early trouble with the law, similar child life experiences, and the same setbacks in life. Some of these problems included drugs, violence, poverty, and an absent father. But the Moore who ended up in prison faced more challenges. His mother was a drug addict; he lived in a very drug-infested neighborhood, and was engaged in the drug trade at a...
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...Type of Activity: Play about Moral value, and moral Law Date: July 06, 2013 Time: 4:30 pm- 6:00 pm Place: MAED, Ground floor of St. Joseph College of Bulacan Activity Details : HRM, and BSTM first year students will make a role play must be show the moral value and moral law. Our NSTP teacher, gave us a time to think and to prepare for our role play. We assigned a role for each other. Our role play start with a boy who met a girl who brings a lot of books in her hand, as having a good ethics he lend the girl a help. The boy asked if he can help the girl then she agree. The man took the books to carrying a woman and brought it to the place where woman go. After he help the girl, the man walked, he saw his friends bullying a student. This incident has been seen also by his girlfriend, his girlfriend wants to tell this to the guidance councilor, but the boy approach her and tell her do not tell the guidance because they are his friends. But the girl know that the right thing to do is to tell it to the guidance councilor, so the woman went to the guidance office and she tell the councilor what has just happened, and the councilor punished those bullies. Reflection: We will learn on how to respect for life, respect others, and respect the authorities. No one should be bullied, we should respect others life as we respect ours. Everyone should be treated equally in a way that in can be justice. Type of Activity: Seminar: Drug Awareness Theme: “Global Action for Healthy...
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...to Kevin and his deviant behavior, but the three theories that I view as the best to explain Kevin’s deviance and behavior that was studied. The three theories that apply best to Kevin’s particular aspects of deviance are Social Bond Theory, Social Learning Theory, and Reaction Formation Theory. Social Bond Theory is a theory that states that if an individual has strong relationships and or bonds , and values, then they will not involve themselves in deviant behavior whether they have deviant friends or not. The theory also says that if the individuals lack these values and or strong relationships, then they fall back on peers in search of those bonds whether they are negative or positive ones. In relationship to Kevin, this theory plays a role in his deviant behaviors because of his relationship with his family and then his involvement in deviant behaviors with his peers. Kevin’s parents were divorced and his mother eventually remarried when he was in the seventh grade. His relationship with his step-father was negative relationships which often lead to arguments and or confrontations between Kevin and his stepfather and Kevin’s mother and step-father, do to his step-fathers alcoholism. Social Learning Theory is a theory that explains individual’s deviant behaviors in terms of an individual behaving in deviant ways and learning deviant behaviors from those individual around them as well as elements of daily exposure to the media. In this particular instance this theory...
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...are genetically predisposed to addictive behaviour. If they use drugs, they are more likely than others to become addicted. However, addiction to a drug is influenced broadly by 3 main factors – the drug, the person and the environment. Drug factors include the drug’s addictiveness, how long you’ve been using it and how much you normally use. Person factors include the role of genetic differences and the individual’s capacity to cope with stresses. And environmental factors include availability of work and social integration Millions of people around the world use drugs and/or alcohol...
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...Time. On the show he plays an important role as a father, husband, and TV show host. What you didn’t see was the things he did off the set of his show. Tim got involved with drugs and from there things went down hill. In this paper I will tell you how he grew up, and what went wrong. Tim Allen grew up just as any other kid would did, playing as a kid and just being a child. In his teen years something tragic happened that would change his life forever. One day out with his friends having a good time, he goes home to find out that his dad had died in a car accident. From then on he used comedy to cover up the pain that he held inside. He started doing stand-up gigs using his comedy around the differences between men and women, using that all too familiar grunt of his. He stayed doing comedy for a while before he was offered a movie part but turned it down. After that he got offered a role to play a role in a new TV comedy series that he would play a role and a TV show host with Benford tools. He took this acting career and it took of for him and so did the show. The show was called Home Improvement and everyone loved it. Little did anyone know what would be coming next in Tim’s life. Once Tim’s acting career took off he was introduced into the fashionable life of an actor. He could have anything he wanted whenever he wanted, he was living the life. The one night after rehearsal for the show he went to a party. At this party Tim was introduced to drugs for the first time...
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...figure, are extremely important in the child’s adolescence and adulthood. In The Other Wes Moore, by Wes Moore, male figures, specifically male role models, play an important part in both Wes Moores’ lives and young boy’s lives in general, eventually making or breaking their future. The author, Wes Moore has many important male role models in his life that enable him to live up to his full potential. Uncle Howard, taking the place of Moore’s deceased father, encourages Moore to strive for higher education over a career in basketball one day as they play the game in their neighborhood. This example clearly depicts the influence of Uncle Howard on Wes Moore, the author, in his education and the influence that eventually earned Moore more opportunities in his later life, such as careers and scholarships. The harsh reality that Uncle Howard speaks to Moore and the emotional support he gives, helps Moore to get back on the right track and create a better and...
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...DRUG ABUSE AMONG UNIVERSITY STUDENTS Introduction As there are so many cases of drug abuse among university students, we need to find out the reasons why they are taking drugs and what can be done to overcome this problem. Body Family factors is one of the reason why university students are taking drugs. Poor parental supervision will give them more opportunities for exposure to drugs. Poor parental communication could lead the children to take drugs. They think their parents do not care about them. Educate your teenager about drug use, so they get the real * facts about the dangers of drug use. Family break up or parental conflicts. Parents keep quarelling everyday. Teenagers who failed to find ways to relief their frustration misuse drugs to feel better (Neil,n.d,as cited in Top 8 Reasons, n.d.) Students may take drugs due to the university factors. Availability of drugs in the university. Other students are selling drugs. They want to try something new. Students are stress in studies. Full of works and assignments. Parents play an important role in preventing or dealing with teenagers who abuse drugs. Talk to your teenager openly and honesty (Stanton,1983) Asking your child to tell you his/her thought and feelings about drugs. Talking with your child about his/her emotion and your feeling too. Teach responsible behaviour. Teach the balance of rights and responsibilities. Give rewards for their responsible behaviour. Encourage your...
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...participants will be asked to share, by group discussion, two examples of positive communication they feel they practice in their daily lives. (Affective, application) 2. At the end of the lesson, participants will be able to practice 3 assertive communication techniques by group mock high stress situation role-play.(Psychomotor, application) 3. At the end of the lesson, participants will role-play a scenario using assertive communication in the workplace. (Psychomotor; application) Aggressive Communication 4. At the end of the lesson, participants will be able to analyze a condition that allows a judge to grant a domestic violence restraining order, as outlined in California Family Code § 6250.3, by presenting a group PowerPoint in front of the class. (analysis, cognitive) 5. At the end of the lesson, participants will name two signs of aggressive communication by writing a group list. (Cognitive; knowledge) 6. At the end of the lesson, participants will be able to identify different anger management techniques by completion of worksheet . (Cognitive, knowledge) 7. At the end of the lesson, participants will be able to walk away from confrontational situations by role-playing a hostile scene in front of the class. (application,...
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...surface and therefore our perception becomes misconstrued sometimes. We see this certain factors in life like sleep deprivation, sickness, and when we are exhausted. This skew the accuracy of our sensory perceptions temporarily, but in many cases they are accurate and the information provided us by senses is important in grounding our thinking. There are also other cases where what we think we see is not really what it is, “habits, interests, and biases, focuses and thus limits our perceptions.” (Kirby & Goodpaster, 2007, pg. 56.) There are many things that can cause an impact to the accuracy of sensory data. The three factors which can contribute to the accuracy of sensory data either positively or negatively are food, drugs and sleep. The first and the most important one is food. The human brain like other body parts needs energy in order to function properly in order to allow our senses to work well. Our brain serves as the seat of human consciousness and therefore stores our memories, helps us to feel emotions, and gives us our personalities. Eating right food with enough protein, sugars and vitamins especially starches will make our brain function very well. Without the good nutrition our brain will lack the necessary energy needed and as result will strongly affect our sensory data. “Without adequate nutrients, intellectual impairment...
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...The definition of a drug addiction is the loss of control over the intense urges to take the drug even at the expense of adverse consequences (Volkow & Li, 2005). The drugs are used multiple mechanisms like positive reward, inhibitory control, and executive function to modulate the brain functions. In this paper, I am going to examine how addictive drugs alter the brain function and result in mediating our behaviors. The primary function of the brain is to monitor the external and internal environment of the individual, then respond to an unconscious and/or conscious level. However, our body requires more complex works for a living. What are the fundamental concepts of how the nervous system mediates behavior? The brain does not work independently...
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...crime. The mistakes often come from what we watch and see in movies and television. We do not realize that organized crime can fall into so many categories. When it comes to organized crime, a lot can come into play. Take into consideration the crimes being committed like murder, drug crimes, and transportation of illegal goods and stolen firearms, those are usually associated with organized crime. Other factors such as behavior can also play a role in organized crime. Many people have a distorted view of organized crime. We watch crime shows that portray organized crime in a few categories, like drugs and murder. My perceptions have fallen into this category. It becomes so common for us to believe what we see in television shows and movies as to it being the real thing. If you look at shows like CSI, the cases they often show deal with the mafia, and drug cartels. While those groups do play a role in those crimes, so do a large number of others. When I think about the mafia and drug cartels, my mind automatically goes to murder. However, the reality is that they are also involved in other criminal acts. There is so much involved in organized crime that we will always be learning as their crimes change. Organized crime, in my opinion, is illegal activities such as drug trafficking, murder, the trafficking of stolen goods and firearms, and kidnapping. These are done by groups that work with families or individuals who control others to help them commit these criminal acts....
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