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Gastric Bypass Surgery and Type Ii Diabetes

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Gastric Bypass Surgery and Type II Diabetes

I chose this topic because of the amount of diabetes in my family. All of my maternal side of the family, except my mother, are diabetic. My father was recently diagnosed. It is of great concern to me as my risk is greater.

The article is based on a study recently published in Science Translational Medicine. The study is small, but states that gastric bypass patients have lower insulin needs then patients who lost the same amount of weight without surgery. In the study, 80 percent of the patients were cured of their type II diabetes. The researchers found that branch-chained amino acids circulating in the bloodstream are greatly reduced in post gastric bypass patients. Apparently the branch-chained amino acids have a greater effect on insulin sensitivity than straight chained amino acids. The gastric bypass surgery drops the level of branch-chained amino acids even before weight is lost. After surgery and weight loss the amount circulating is even lower then in patients who just lost the same amount of weight. The scientists can’t explain why the surgery itself makes the change in amino acids. One theory is that there is a change in the hormones in the stomach that affect branch-chained amino acids. Another theory is that perhaps a change in bacteria in the stomach could account for the decrease in amino acids. This is interesting because, if the scientists can figure out why the branch-chained amino acids drop even before weight loss, maybe the surgery will become unnecessary. This would be better for most obese people, because the surgery is dangerous. If the same results can be found with a shot or pill, more people could be cured of Type II Diabetes. The problem is that surgery is very expensive and dangerous.

I will continue to follow this research. The fact that both sides of my family have diabetes

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