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How to Get Out of Jail

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Submitted By ahassett16
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Chromatography
Aim: To test the purity of aspirin using chromatography.
Vocational context
The results which we have collected while doing this chromatography will be helpful to many different types of people. One group of people who will be interested in the results is doctors when a patient comes to visit the doctor with a virus or something the doctor can look at these results and they will be able to make a decision on how powerful the aspirin to give the patient. Another group of people who might take an interest to these results are drug testers

Background science Aspirin also known as acetylsalicylic acid, is a salicylate drug, often used as an analgesic to relieve minor aches and pains, as an antipyretic to reduce fever, and as an anti-inflammatory medication. Aspirin separates and decomposes very quickly in hydroxide and alkali metals. Aspirin is stable in dry air but gradually hydrolyses when it comes into contact with moisture

Chromatography can be used to separate mixtures of coloured compounds. Mixtures that are suitable for separation by chromatography include inks, dyes and colouring agents in food. There is two phases the mobile phase which flows through column, carries analyte and the stationary phase which stays in a place, does not move. The separation of the molecules is based on the partitioning between the mobile and stationary phase. Chromatography is used in labs often to separate different compounds
A TLC plate is a sheet of glass, metal, or plastic which is coated with a thin layer of a solid adsorbent (usually silica or alumina). A small amount of the mixture to be analysed is spotted near the bottom of this plate. The TLC plate is then placed in a shallow pool of a solvent in a developing chamber so that only the very bottom of the plate is in the liquid. This liquid, or the eluent, is the mobile phase, and it slowly

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