...Pancreatic cancer is the fourth leading cause of cancer death in men and women with an estimated death rate of around 43,000 this year alone. Patients are usually asymptomatic until the disease progresses which is why this cancer has such a poor prognosis and why I believe education and changes in modifiable risk factors is key for prevention and awareness of this deadly disease. Pancreatic cancer occurs when cells establish variations in their DNA and the variations cause the cells to grow uncontrollably and continue living even after normal cells would die. These abnormal cells can form a tumor. Most of the time the cancer begins in the cells that line the ducts of the pancreas. This type of cancer is called pancreatic adenocaricnoma or...
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...Pancreatic Cancer Research Grad2016 Abstract This paper is looking into the effects of pancreatic cancer and the research behind it. Pancreatic cancer is one of the most deadly forms of cancer known and contributes to over 30,000 deaths a year in the U.S. alone. Little is known about this killer cancer or of an accurate treatment. Unfortunately this disease has a very low survival rate even with treatment. There are several benefactors associated with this disease that we will discuss as well. These include alcohol abuse, genetics, tobacco, diabetes and lifestyle. There is a lot of research being conducted on this killer disease with hopes of increasing the survival rate with a cure or early diagnosis. One of the most deadly cancers is known as Pancreatic Cancer. This type of cancer is confined to the pancreas and is responsible for thousands of deaths every year. Little is known about the true cause of pancreatic cancer or a curable treatment. One of the reasons it is associated with the most deadly cancers is the fact that even with treatment it still has a very low survival rate. According to H. Chang (2007) only 10-15% of patients can expect to be cured by treatment. Out of the 30,000 plus patients that are diagnosed each year that is a very low survival rate. Pancreatic cancer is very hard to diagnose at an early stage because there is no precursor standard that is associated with it. Recent research has identified an association with hyperglycemia with patients...
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...Her Last Days Jody Seibold Hondros College Abstract My research paper is dedicated to my mother and her last days on this earth. Our nightmare started on September 17, 2012, this is when we were told that my mom had stage four pancreatic cancers that had spread to all of the lobes of her liver, spleen, and large intestine. We went to this appointment thinking she would be able to be treated not to get a death sentence. By the time we found out her cancer had already spread. She was offered chemotherapy but she declined it because at best, it would only prolong her life a month maybe two. She wanted to live her life to the fullest and not be sick from chemo. At that moment every minute was precious time left with mom and I wanted to be by her side every minute of every day. This is the true story of a beautiful life cut short from cancer. Her Last Days This research paper will explain the main function of the pancreas and why pancreatic cancer is it so deadly? It will reveal how a person can live without a complete pancreas? This essay will cover the five stages of grief my mother experienced. I will attempt to explain the emotional aspect my mother went through. It will also talk about hospice and how they assisted us through the process. Lastly, my paper will cover how strong my mother’s faith in God was and still is. What is the main function of the pancreas? This gland is positioned in the epigastric portion of the abdomen tuck in behind the stomach (NCBI...
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...Analysis of Current Pancreatic Cancer Screening Methods & Future Recommendations ABSTRACT PAGE Objective Background Results Conclusion (1) what the objectives of the study were; :) (2) how the study was done; --- (3) what results were obtained; (4) and the significance of the results. Treatment for pancreatic cancer is often no longer viable (practical) by the time the condition can be diagnosed. This is due to the lack of effective screening methods to detect the tumor or cyst in its earliest curable stages. The ability to successfully detect pancreatic cancer is highly dependent on an effective screening method with high sensitivity and specificity that can detect the tumor or cyst early in its development. In the United States, many of the current methods are too costly, too invasive, unavailable for widespread use, and lack high sensitivity and specificity. There is a strong need to find a more promising screening method that is inexpensive, noninvasive, available for widespread use, and maintains high sensitivity and specificity. The immediate objective of this research project was to evaluate the current screening methods and make a recommendation for a future screening strategy with strong potential to detect the cancer in its earliest stages while improving the sensitivity and maintaining high specificity. The first step in the investigation process was to identify a high-risk population for pancreatic cancer. Then, current screening methods were...
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...Obesity and Cancer According to the National Institute of Health, nearly two-thirds of adults in the United States are overweight or obese (2007). Research suggests that obesity may be the most preventable risk factor of cancer for non-smokers, and many studies are testing for the effects that obesity has in all cancers and at specific cancer sites. It is known that obesity plays a significant role in cancer; however, the knowledge of the relationship to all cancers and the overall health effect of excess weight in terms of total mortality from cancer is limited (Calle, Redriguez, Walker-Thurmond, & Thun, 2003). In this paper I will examine the research available on obesity and its relationship to breast cancer (in post-menopausal women), endometrial, colon, esophagus, kidney, and pancreatic cancers, and briefly mention a few other cancers currently being studied for a possible link to obesity. The rise of obesity in the last 25 years has been most prominent in the United States. It is not, however, limited to the United States; for instance, similar trends are being seen in other developing countries. As it becomes easier to access tasty but unhealthy food options and as physical activity declines, caloric intake is now exceeding caloric expenditure. Genetic factors have been shown to predispose an individual to become obese, but environmental factors are the ultimate cause for the rise of obesity within populations. It is the metabolic consequences of obesity that are...
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...of adults in the United States are overweight or obese (2007). Research suggests that obesity may be the most preventable risk factor of cancer for non-smokers, and many studies are testing for the effects that obesity has in all cancers and at specific cancer sites. It is known that obesity plays a significant role in cancer; however, the knowledge of the relationship to all cancers and the overall health effect of excess weight in terms of total mortality from cancer is limited (Calle, Redriguez, Walker-Thurmond, & Thun, 2003). In this paper I will examine the research available on obesity and its relationship to breast cancer (in post-menopausal women), endometrial, colon, esophagus, kidney, and pancreatic cancers, and briefly mention a few other cancers currently being studied for a possible link to obesity. The rise of obesity in the last 25 years has been most prominent in the United States. It is not, however, limited to the United States; for instance, similar trends are being seen in other developing countries. As it becomes easier to access tasty but unhealthy food options and as physical activity declines, caloric intake is now exceeding caloric expenditure. Genetic factors have been shown to predispose an individual to become obese, but environmental factors are the ultimate cause for the rise of obesity within populations. It is the metabolic consequences of obesity that are having an effect on cancer cell growth. The effects of circulating peptide and steroid hormones...
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...Vol 450 | 20/27 December 2007 | doi:10.1038/nature06385 LETTERS Isolation of rare circulating tumour cells in cancer patients by microchip technology Sunitha Nagrath1*, Lecia V. Sequist2*, Shyamala Maheswaran2, Daphne W. Bell2{, Daniel Irimia1, Lindsey Ulkus2, Matthew R. Smith2, Eunice L. Kwak2, Subba Digumarthy2, Alona Muzikansky2, Paula Ryan2, Ulysses J. Balis1{, Ronald G. Tompkins1, Daniel A. Haber2 & Mehmet Toner1 Viable tumour-derived epithelial cells (circulating tumour cells or CTCs) have been identified in peripheral blood from cancer patients and are probably the origin of intractable metastatic disease1–4. Although extremely rare, CTCs represent a potential alternative to invasive biopsies as a source of tumour tissue for the detection, characterization and monitoring of non-haematologic cancers5–8. The ability to identify, isolate, propagate and molecularly characterize CTC subpopulations could further the discovery of cancer stem cell biomarkers and expand the understanding of the biology of metastasis. Current strategies for isolating CTCs are limited to complex analytic approaches that generate very low yield and purity9. Here we describe the development of a unique microfluidic platform (the ‘CTC-chip’) capable of efficient and selective separation of viable CTCs from peripheral whole blood samples, mediated by the interaction of target CTCs with antibody (EpCAM)-coated microposts under precisely controlled laminar flow conditions, and without requisite...
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...today than ever. Indeed, the abrupt departures of two important charismatic CEOs – Charles Prince of Citygroup and Stanley O’Neal of Merrill Lynch – in the aftermath of the 2008 financial crisis, which fetched these firms colossal losses have made scholars to beam their searchlight on this neglected aspect of corporate governance. The nonchalance with the way some CEOs handle the process of succession planning not only puts their companies in jeopardy, but also signposts a major criterion on which outgoing CEOs and their executive board members will be evaluated. Before we proceed, we will issue a caveat: the practice of succession planning runs ahead of the theoretical understanding of the process. In fact, in the course of this research, we did not come across a single work on charismatic leaders. However, we did come across pockets of literature on CEOs and succession planning. It is from these literature and articles from reputable magazines like the Economist, Forbes and the Wall Street Journal that we extrapolated our...
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...proficiency test and are licensed to practice nursing. They both have in most cases the same job titles and duties. However the difference between these two nurses are the educational levels attained. The BSN nurses has educational background that prepares them to be ready for the demands of the job. As they take more core classes which shape and build their skills as nurses. Education and training. The commitment require to become a baccalaureate degree nurse is more than that of an associate degree nurse, BSN nurses are in school for four years where as an associate degree program takes two years. They take more humanitarian and social science classes, as well as classes expanding deep into theory, evidence based practice, nursing research and patient care. The baccalaureate students also are able to build and learn leadership and managerial skills through team projects that they are required to participate in during their study. They are able to develop strong critical thinking skills and problem solving skills within the four year period. Unfortunately ADN programs focus directly on the basic nursing skills, how to perform, duties, techniques and procedures as nurses. . Job opportunities and career advancement. BSN nurses have the opportunity to choose from various positions as nurses. They can either work as a floor nurse, a nurse educator, or in case management. They have the chance to also work in public health where they can educate the community on health issues...
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...Alcohol as among the drugs that are been abused in large number and has become a major ill in our society. Alcohol destroys the lives of their victims in many ways. Alcoholism is the later stage after been addicted to alcohol but it can be recovered but it needs self discipline. Contents: Page: 1. Introduction……………………………………………………………. 3 1.1. Definition of alcohol…………………………………………………. 3 2.0. Effects of alcohol…………………………………………………….. 3 2.1. Healthy effects of alcohol……………………………………………. 4 2.2. Social effects of alcohol……………………………………………… 4 3.0. Alcoholism…………………………………………………………… 5 4.0. Causes of Alcoholism………………………………………………... 5 4.1. Social and Emotional causes of Alcoholism………………………… 6 5.0. Ways to recover from Alcoholism…………………………………… 6 6.0. Conclusion…………………………………………………………… 7 INTRODUCTION Drug abuse is an intense desire to obtain increasing amounts of a particular substance or substances to the exclusion of all other activities. According to WHO “Drug abuse has become a major ill in our society; it destroys the lives of their victims in many ways because these chemical substances are not intended to be introduced into the human body and as a result weakens the body system for instance the heart, lungs, liver, kidneys and brain are often damaged by heavy drug use and all of these organs are vital for life. Due to the broad case with drugs, I have chosen alcohol as an example of drugs been abused in the society. What is alcohol? According to Buddy. T...
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...in absentia by attending classes at the MBL. He only needed one year of official residence in Chicago before applying for his Ph.D. Two of Just’s articles were accepted for his doctoral thesis, titled “Studies of Fertilization in Platynereis megalops”, and he received his Ph.D. in June (Just, Ernest Everett). Ernest Everett Just explored many topics related to physiology of development such as, experimental parthenogenesis, hydration, fertilization, and cell division (Ernest Everett Just Biography). Throughout his life Just had enrolled in multiple biology and zoology courses and showed promising results and interest in both. Notably at Woods Hole he studied and researched biology and zoology in the summers and even wrote a scientific paper on the division is...
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...Alexa Anastasi December 8, 2014 English 1A Research Paper Diet and Cancer: The Fascinating Connection What’s on your plate? That seems to be the overwhelming question in today’s society filled with both health food conscious people and those individuals who do not care and eat junk food most of the time. However what most of these people do not realize is that they are not only jeopardizing their health and decreasing their life expectancy but they are also increasing their chances of getting some form of cancer in their lifetime. The individuals who fuel their bodies with high calorie sugary drinks, fats and processed meats are not doing their bodies any justice they are just fueling the dormant cancer cells in their bodies to run rampant throughout their body and causing something that could have been easily prevented with a change in diet. On the flip side, the health conscious people in the world are already ten times more protected from cancer because of the healthy lifestyle choices they make every day! Don’t be a contributor to America’s high cancer rate, be a game changer and live your life to the fullest with little possibility of cancer, all you have to do is eat those delicious and nutritious fruits and vegetables that can be found all around you! Why would you want to put another hamburger or hot dog in your mouth knowing it has the potential to kill you? I know I wouldn’t because I love my body too much and you should too! So climb on board and let me...
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...BIO 1 Paper Stem Cells Research WHAT ARE STEM CELLS? * Stem cells are biological cells found in all multicellular organisms, that can divide through mitosis and differentiate into diverse specialized cell types or can self renew to produce more stem cells. * In mammals, there are two broad types of stem cells: embryonic stem cells that are isolated from the inner cell mass of blastocysts, and adult stem cells that are found in various tissues. * In adult organisms, stem cells and progenitor cells act as a repair system for the body, replenished in adult tissues. In a developing embryo, stem cells can differentiate into all the specialized cells, but also maintain the normal turnover of regenerative organs, such as blood, skin, or intestinal tissues. Properties The classical definition of a stem cell requires the following properties: * Self-renewal - the ability to go through numerous cycles of cell division while maintaining the undifferentiated state. * Potency - the capacity to differentiate into specialized cell types. In the strictest sense, this requires stem cells to be either totipotent or pluripotent - to be able to give rise to any mature cell type, although multipotent or unipotent progenitor cells are sometimes referred to as stem cells. In Self-Renewal.. Two mechanisms exist to ensure that the stem cell population is maintained: * Obligatory asymmetric replication - a stem cell divides into one father cell that is identical...
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...AN EFFECTIVE RESEARCH PROPOSAL The purpose of this handout is not to teach you how to design a research project. Rather it is to help you translate your research plans into an effective research proposal. A well-written proposal will ease the process of obtaining institutional and ethical approval and will increase your chances of obtaining funding for your project. The writing of this booklet was guided by our experience writing proposals but also on our experiences as reviewers on institutional and granting agency review panels. The booklet is designed for health sciences researchers conducting quantitative, clinical research. However, the general concepts are applicable to most areas of inquiry. Writing an Effective Research Proposal 2 ELEMENTS OF A RESEARCH PROPOSAL ∗ ∗ ∗ ∗ ∗ ∗ ∗ Title Abstract Study Problem Rationale/Relevance of the Project Literature Review Specific Study Objectives Research Methods I. Study design II. Subjects Inclusion/exclusion criteria Sampling Recruitment plans Method of assignment to study groups III. Data collection Variables: outcomes, predictors, confounders Measures/instruments Procedures IV. Intervention V. Statistical considerations Sample size Data analysis Ethical Considerations Consent form Privacy of information Work Plan Budget Research team Dissemination Plan 3 ∗ ∗ ∗ ∗ ∗ Writing an Effective Research Proposal KEYS TO SUCCESS TO WRITING A GOOD PROPOSAL Overall Quality of the Study ∗ Good research question ∗ Appropriate...
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...The Last Lecture: The last lecture is a series of lectures that have been established by Carnegie Mello University for the retiring professors to talk about their insights into the life. In this lecture, professor of computer science Randy Pausch was enforced to deliver a very literal last lecture after facing a diagnosis of terminal pancreatic cancer. This lecture was entitled as "Really Achieving Your Childhood Dreams". Randy start his lecture in a professional way to inspire the audience, he told them about his cancer and that the doctors informed him he has few months to live. But he was very optimistic and wanted to approve to everyone that he is in a good shape by doing push-ups. Randy introduced the idea of “elephant in the room” in a slide he presented of his CAT scan with arrows pointing to the ten identified tumors. As he told the audience that “We cannot change the cards we are dealt, just how we play the hand.” Three topics his lecture was about; first, his childhood dreams and how he achieved them. Second, enabling the others achieve their dreams. Third, the lessons he learned in his life. First, he talked about his childhood dreams. being in zero gravity, playing in NFL, being an author in world book encyclopedia, being captain Kirk, winning stuffed animals and being a Disney land imageneer. The first dream he achieved by working with his students to win competition announced by NASA by providing the best proposal, he was determined to have the experience...
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