...Wuanda S Green Introduction to Biology Dr. Russell Barnett Personalized Medicine Personalized medicine is a new field of healthcare that is based on an individual’s unique genetic, genomic, clinical and environmental information. The factors vary from one person to another just like the onset of diseases so the purpose of personalized medicine is to react to the individual’s symptoms in the way, with personalized treatment (Jain, 2007). Personalized medicine primary goal and target is to make a treatment as individualize as the person receiving the treatment. This method involves identifying genetic, genomic, and clinical information that will allow accurate predictions to be made about an individual’s susceptibility to a developing disease, the course of that disease and the response to treatment (Cohen, 2008). Modern genetic technology started with the genome project which leads to the benefits and development of personalized medicine (Cohen, 2008). The human genome is the blueprint for each person's body, influencing how we look, our genetic predispositions for certain medical conditions, how well our bodies fight disease or metabolize food, and which therapies our bodies do and do not respond to (Hart, 2005). The genome consists of an organism's total DNA, including its genes. DNA—the famous "double helix"—is composed of four chemicals, which are repeated many times in different sequences (Jain, 2007). (The names of the chemicals are abbreviated as A, T, C, and G. That's...
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...and Disease Management Systems make personalized medicine and personalized diagnostics possible. Moreover, healthcare practice move from cure to prevention. These changes require expertise in biomedical sciences rather than in engineering and physics; and also investment, collaboration with pharmaceutical companies which facilitate the creation of imaging equipment necessity to alter GEMS business model which is away from engineering heritage toward bio-chemistry and develop drug based on genetic code for specific individual, or small group rather than entire population. b. Demographic change: + Population were aging in advanced nation, implied fewer working-age people to pay for more intense care while the emerging middle-classes if Asia, Eastern Europe and Latin America were increasingly aware of, and needed, better healthcare. This requires the shift in distribution of healthcare equipment in these countries (more for Asia, Eastern and Latin America) and the change in market segment of healthcare equipment. + Global information flows made healthcare disparities between developed and developing nations more stark and unacceptable. Thus, concentrating more on developing world needs great effort investment and customization. c. Fierce competition: + Siemens is leading in healthcare IT, which is a great advantage for them to thrive in technological change era. All competitors move on healthcare IT segment, potentially affecting the market share of GEMS. 2. Strengths and...
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... kill thousands of people every day Mosquito-borne diseases hospital-acquired infections 100,000 patients die each year from causes more than 250,000 deaths each year Seasonal flu Medical Model A leap in the evolution of healthcare enabling care providers to deliver the right treatment to the right patient at the right time. 1: IT-enabled Personalized Healthcare 2: Adoption of Electronic Medical Records 3: Disease-Centric to Prevention-Centric NOW CONSUMER CONSUMER FACILITY CONSUMER CONSUMER FUTURE CONSUMER The Digital Hospital Paperless Wireless Long-distance robotic surgery Vivid 7 Cardiovascular Ultrasound System Real time. Real solutions. Real value. VSCAN Pocket-sized, ultra-smart ultrasound Provide an immediate look inside the body Through the Adventure Series, the hospital is working to create fun, soothing care environments for child patients. Medical Model A leap in the evolution of healthcare enabling care providers to deliver the right treatment to the right patient at the right time. 1: IT-enabled Personalized Healthcare 2: Adoption of Electronic Medical Records 3: Disease-Centric to Prevention-Centric One Consistent Problem One of the main reasons illegible lab reports repeat prescription forms & waiting for insurance companies to deny your claims ON THE ST 1 ATTEMPT A large portion of these are...
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...means ensuring the right service is efficiently provided at the right time, in the right place, by the most appropriate and least expensive combination of health care providers. One aspect of these emerging trends is Point-of-Care (POC) testing and POC diagnostics. For many years laboratory testing was performed by technologists in a central laboratory. This was necessary because of the complexity of the testing. Computer technology has now taken analysis from the laboratory to the patient’s bedside, the doctor’s office or the patient’s home. This testing is called point-of-care testing (POCT) and is defined as testing at the point where patient care is given, wherever may be. The POCT results are timely, allowing more time for rapid treatment of the patient. It empowers clinicians to make decisions at the “point-of-care” and has the potential to significantly impact health care delivery and address the challenges of health care disparities. The success of this potential shift from curative medicine, to predictive, personalized, and preemptive medicine relies on the development of portable diagnostic and monitoring devices for point-of-care testing. Our parent’s knew point of care testing as it was the way that medicine was delivered in the patient’s home through physician...
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...attempts to make use of the firm’s unique competencies by accepting a portfolio to the business management by developing long term plans. And the middle is the decision-making hierarchy at business-level that translates the statement’s direction and generates corporate-level strategies for business units or SBUs. And the bottom hierarchy is functional-level that develops short term strategies and annual objectives in different areas of organisation. (David, 2003) II. ORGANIZATION & BUSINESS SEGMENTS Company Profile Johnson & Johnson- A most comprehensive health-care firms in the world and most diversified. J&J manufactures health care products for consumer & personal care, pharmaceutical, medical devices and diagnostics markets. It is operating its firms in 57 countries and nearly 200 companies around the world. J&J generates nearly half of its revenues from outside US; through its operating networks and marketing organizations that sells products in 175 countries. (Web 1) Key Facts- Johnson & Johnson Incorporated | 1887, Public Company | Employees | 114,000 | Sales | US $63.7 billion | Net earnings | US $12.9 billion | Stock Exchanges | New York Toronto | Operating locations | 57 Countries | Ticker Symbol | JNJ | Mission- To improve the quality of life for, people at everywhere. Vision- Bringing science to the art of healthy living life. The mission and vision statement shows that J&J gives importance on...
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...decision in retrospect. The life sciences and chemical analysis units now collectively generate half of the company’s sales, and allowed Agilent to remain profitable despite the collapse of the electronic measurement unit’s profits during the financial crisis. As one of many examples, this illustrates the growing importance of the medtech segment, which is gaining attention of industry groups from various sectors. What factors make medical technology so attractive? Which industries can benefit from expansion into this segment? DEFINITION Segmentation Medical technology is a widely used term but definitions and segmentations aren’t always consistent. Novumed’s comprehensive segmentation of the medical technology market differentiates between diagnostic and therapeutic products and, on the next level, between devices and consumables. 2 Medical...
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..."Concierge Medicine, A Solution, Or A Problem?" The landscape for health care delivery has evolved significantly over time. What initiated as a home service by a family physician grew into predominately inpatient service, followed by the expansion of outpatient service. Now, the trend is starting to drift back to a more "family physician" approach with an added cost. Reduced reimbursement rates, increased paperwork, increased operating costs, and increased patient case loads have made it difficult for primary care physicians (PCPs) to be successful compared to their peers. Medicare and Medicaid reimbursement rates continue to be adjusted downward, and PCPs are expected to broaden their practices to compensate. Medical school graduates are choosing careers as specialists for an increased income, stability, set hours, and reduced case loads. As a result, the decline of PCPs has increased resulting in fewer providers coupled with a growing population. Those providers remaining in the PCP field, or deciding to enter that area of service, are looking for new ways to generate revenue and reduce the patient case load. As a result, concierge medicine, also known as boutique medicine, retainer medicine, VIP medicine, executive health program, platinum practice, personalized health care, or luxury health care, has evolved and is currently growing (Harris, 2008). Reasons for the shift in care are continued downward pressure on health plan reimbursement rates both from private...
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...mdpi.com/journal/ijerph Article Emerging Patient-Driven Health Care Models: An Examination of Health Social Networks, Consumer Personalized Medicine and Quantified Self-Tracking Melanie Swan * Research Associate, MS Futures Group, P.O. Box 61258, Palo Alto, CA 94306, USA * Author to whom correspondence should be addressed; E-Mail: m@melanieswan.com; Tel.: +1-415505-4426; Fax: +1-504-910-3803 Received: 9 January 2009 / Accepted: 2 February 2009 / Published: 5 February 2009 Abstract: A new class of patient-driven health care services is emerging to supplement and extend traditional health care delivery models and empower patient self-care. Patient-driven health care can be characterized as having an increased level of information flow, transparency, customization, collaboration and patient choice and responsibility-taking, as well as quantitative, predictive and preventive aspects. The potential exists to both improve traditional health care systems and expand the concept of health care though new services. This paper examines three categories of novel health services: health social networks, consumer personalized medicine and quantified self-tracking. Keywords: Patient-driven health care; health social networks; personalized medicine; quantified self-tracking; health care delivery; predictive health care; preventive health care; long-tail medicine; Internet; open source. 1. Introduction The life sciences field is advancing and changing in nearly every dimension, both content-wise...
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...second hospital also has a strong orthopedic program and existing cardiology program. This hospital also has a poorly organized oncology program. Building space for oncology service will allow patients to easily coordinate with services already within the hospital and make use of the newly improved and more developed resources within Trinity Community Hospital. The Community Health Needs Assessment identified that the orthopedic cases are expected to rise by over 46%, inpatient joint and spine procedures by 30%, and outpatient joint and spine procedures by 350% in the next five years. However, there are existing nearby facilities that already cater to this market, some well-renowned. The Needs Assessment also identified, in terms of cardiology services, coronary artery disease is expected to grow over 21%, diagnostic cath procedures by at least 22%, and angioplasties by...
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...2014-2018 Global Polymerase Chain Reaction (PCR) Market EMISPDF us-thermo-url from 208.89.140.11 on 2014-11-24 17:09:41 GMT. DownloadPDF. technavio insights Downloaded by us-thermo-url from 208.89.140.11 at 2014-11-24 17:09:41 GMT. EMIS. Unauthorized Distribution Prohibited. 2014-2018 Global Polymerase Chain Reaction (PCR) Market Table of Contents 01. Executive Summary.......................................... 1 02. List of Abbreviations ......................................... 2 03. Scope of the Report.......................................... 3 03.1 Market Overview .......................................................... 3 03.2 Product Offerings .......................................................... 3 04. Market Research Methodology ..................... 6 04.1 Market Research Process .......................................... 6 04.2 Research Methodology .............................................. 6 05. Introduction ....................................................... 8 06. Market Landscape ........................................... 9 06.1 Market Overview .......................................................... 9 06.2 Market Size and Forecast........................................... 9 06.3 PCR Market in US ........................................................ 10 06.3.1 Mark et Size and Forecast .................................................. 10 06.4 PCR Market in Europe..........................................
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...The Johnson & Johnson vision is to maximize the global power of diversity and inclusion to drive superior business results and a sustainable competitive advantage. Our Global Diversity and Inclusion Vision Statement, which can be read in its entirety below, identifies our commitment to cultivate a diverse and inclusive culture reflective of our dynamic global marketplace. The Johnson & Johnson Family of Companies will realize this vision by: * Fostering inclusive cultures that embrace our differences and drive innovation to accelerate growth; * Achieving skilled, high performance workforces that are reflective of the diverse global marketplace; * Working with business leaders to identify and establish targeted market opportunities for consumers across diverse demographic segments; and * Cultivating external relationships with professional, patient and civic groups to support business priorities. The environment is the ultimate human health issue. As the world’s largest health care company, Johnson & Johnson recognizes the critical interdependence between human health and the health of our planet. We believe a healthy planet and a healthy community go hand in hand. That’s why we are committed to reducing our environmental impacts across all aspects of our operations – striving for performance that does not merely comply with regulations but protects and nurtures the planet’s beauty and resources for future generations. Guided by our...
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...Should Genes be Patented? Patenting genetic discoveries have proven to be controversial throughout the years. There are now patents that are associated with many of the genes within the human genome. Patents are issued to encourage innovation and protect those investing in genetic research the opportunity to maximize profit. During this period, another party can use the discovery to develop a product only with a licensing agreement; however, basic researchers can use it freely. Some argue that this period of exclusivity fosters commercial development of the discovery by discouraging competition. Yet the patenting of genes is not without controversy. Some reject the entire concept of patenting, while others have objections to the patenting of only specific types of DNA sequences. It has also been argued that patents inhibit or limit biomedical research all together. The patenting of human genetic material raises complex social, ethical, and policy issues such as the potential for discrimination in access to healthcare services or employment, and the implications for ongoing research and access to services. The patentability of inventions concerning human genetic material is determined by the US Patent and Trademark Office (USPTO). To obtain a patent, the invention must meet four criteria. The invention must be “useful” in a practical sense, “novel” (not known or used before filing), “nonobvious” (not an improvement easily made by someone trained in the relevant area), and the...
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...The Future of Cardiovascular Diagnostics THE MARKET, TRENDS & FUTURE DIRECTIONS Extracted on: 20 Apr 2011 Reference Code: BI00021-008 Publication Date: 02 Mar 2010 Publisher: Datamonitor © Datamonitor This content is a licensed product, no part of this publication shall be reproduced, sold, modified or stored in a retrieval system or transmitted in any form by any means, electronic, mechanical, photocopying, recording or otherwise, without the prior permission of Datamonitor. The information in this document has been extracted from published research by a registered user of the Datamonitor360 platform. Datamonitor shall not be responsible for any loss of original context and for any changes made to information following its extraction. All information was current at the time of extraction although the original content may have been subsequently updated. Please refer back to the website http://360.datamonitor.com/ to view the most recent content and the original source of the information. To the maximum extent permitted by applicable law we exclude all representations, warranties and conditions relating to the facts of all publications. At time of publication no guarantee of accuracy or suitability, whether express or implied, shall attach to this publication (including, without limitation, any warranties implied by law of satisfactory quality, fitness for purpose and/or the use of reasonable care and skill). Please note that the findings, conclusions and recommendations...
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...Interpretation Reinterpretation Creativity Spontaneous Induced Challenges Unmet Needs Financial opportunity Entrepreneurship Corporate directives Government Agency directives Competition Crises Fear So What’s Next? Healthcare (Medicine) has to actively adopt Innovation in its teaching and culture, rather than letting it occur passively Innovation is needed to overcome the many stresses that exist on Healthcare (Medicine) today Healthcare Innovation - takes many forms Incremental : Adding a new feature to an existing product Examples: Next generation pacemaker that are safe for MRI, Biodegradable, diagnostic stents Healthcare Innovation - takes many forms Disruptive: New value creation, paradigms change Example: DES, TAVI It is difficult to foresee Disruptive Solutions They are rare to find: Requires excellent access to the best deal flow and deep intuition about the relevant markets The validity of their claim is more difficult to substantiate : Requires more thorough due diligence Development and execution risks are bigger : Needs better team and more focused entrepreneurs This is the ultimate challenge for early stage VCs: Market intuition > Technology validation > People assessment Healthcare Innovation In healthcare, we’ve innovated new technologies and products While innovation in service and business models has lagged Core Challenges: Serve larger populations with...
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...Pharmacogenomics 1.Introduction: Genomics: The study of genes and their function. Genomics aims to understand the structure of the genome, including the mapping genes and sequencing the DNA. Genomics examines the molecular mechanisms and the interplay of genetic and environmental factors in disease. It is used to determine the entire DNA sequence of an organisms and a fine scale genetic mapping. The field also includes study of intra genomic phenomena such as Hetrosis, Epistasis, Pleiotropy and other interactions between loci and alleles within the genome. 2.History: The term genome was introduced by H. Winkler in 1920 to denote the complete set of chromosomal and extra chromosomal genes present in an organism, including a virus. This term is used in the same sense even today. The term genomics was coined by T.H. Roderick sometime in 1987 mean mapping and sequencing to analyze the structure and organization of genomes. But today genomics includes sequencing of genomes, determination of the complete set of proteins encoded by an organism, and the functioning of genes and metabolic pathways in an organism. Thus genomics not only deals with the determination of the genetic information present in an organism, but also with the understanding the mechanism by which this information is used by the organism. A major branch of genomics is still concerned with sequencing the...
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