Recent Research in Science and Technology 2011, 3(4): 155-157 ISSN: 2076-5061 www.recent-science.com

PHARMACY CARDIOTONIC ACTIVITY OF COCONUT WATER (COCOS NUCIFERA) Hemanth Sairam Pattigadapa∗, M. Ramesh, C.H. Praneeth Sagar, U. Bhaskar Rao, G. Lakshman, M. Ankaiah, J. Balu Naik

1Sree college of Pharmacy, Nayakulagudem (vil.), Khammam (Dist.), A.P. (State), India

Abstract The coconut (Cocos nucifera) is a member of the family Arecaceae (Palm family). Various parts of this tree is used in the treatment of, cancer (due to hexane fraction of coconut peel), indomethacin-induced ulceration (coconut milk).Coconut water consumption reduces diastolic blood pressure (due to the presence of potassium).In the present work fresh coconut water, dilution 1:1(coconut water: distilled water), are used to evaluate cardiac activity on the isolated frog heart and are labeled as T1, & T2 respectively and compared with Digoxin (S1) as standard solution. It was found that sample T1(Undiluted coconut water) showed better response as compared to the diluted coconut water(T2).These preliminary studies confirm the cardiotonic activity of the coconut water(Cocos nucifera).

Keywords: Physical properties, Jakekur, Water, Quality

Introduction The cardiovascular system includes the heart, blood vessels, spleen, and lymphatic system. The main function of this system is to maintain homeostasis by acting as a transportation system that carries needed materials to cells and removes waste materials from cells.1,2 The conduction system functions by Initiating the heart beat, Conducting messages around the heart, Coordinating beats between the atria and ventricles. Various diseases related to cardiovascular system are aneurysm, arthrosclerosis, cardiac arrhythmia, congestive heart failure, hypertension, myocardial infraction (heart