...What Is Resveratrol? Resveratrol is loaded with antioxidant properties that can help neutralise free radicals that are said to be the cause of ageing. Resveratrol comes from a natural compound found in red grape skin. Resveratrol can also be found in peanuts, berries and other sources. It belongs to a group of plant compounds known as polyphenols. Polyphenols helps protect the body by lowering the risk of cancer and cardiac diseases. Resveratrol is also a phytoalexin, it acts as antibiotic produced in plants under stress, in cases such as fungal attack, ultraviolet irradiation, or inflammation. The molecule present aids the plant to fight back and maintain good health. Why are Antioxidants Important? Antioxidants are the real deal when you want to slow the so called ageing and stay as young-looking as possible. It can exceptionally help to repair the damage caused by free radicals. Our body is continuously replacing and repairing the damages caused by free radicals. However, the reason why we are bombarded with free radicals is the way we...
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...New insights into how cells cope with stress could help combat neurological diseases and reduce the ravages of aging. Scientists have known for years that moderate stressors, such as a calorie-restricted diet, increase lifespan in a variety of organisms. Now new research is illuminating how this works at the molecular level. A particular protein is key in regulating at least one aspect of the stress response and may be a good model for anti-aging drugs. "What we have here is an essential protective pathway that now looks like a very effective therapeutic target," said biologist Richard Morimoto of Northwestern University. Most research on this protein, called sirtuin1 (SIRT1), has concentrated on its ability to regulate and protect mitochondria — cellular power generators that are corroded over time by reactive oxygen molecules. But SIRT1 also protects DNA in the cell nucleus. Morimoto’s findings, published Thursday in Science, give a precise mechanical explanation for the effects. Cells have evolved a particular response to stay alive in adverse conditions. When a cell starts getting too hot, too hungry or too oxygen-deprived, certain proteins migrate into the nucleus. There, they latch onto sections of DNA and cause heat-shock proteins to be produced. Heatshock proteins — so named because they were first discovered in cells experiencing high temperatures — cruise around the cell, fixing damaged or improperly folded proteins. "Proteins are very delicate," Morimoto said. "Any...
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...Confirming Pages bye80180_appB_539-654.qxd 11/19/09 9:17 AM Page 539 technology ventures - management dell’imprenditorialità e dell’innovazione Richard C. Dorf, Andrew J. Nelson, Roberto Vona Copyright © 2011 – The McGraw-Hill Companies srl A P P E N D I X B Cases 539 bye80180_appB_539-654.qxd 11/19/09 9:17 AM Page 540 Confirming Pages technology ventures - management dell’imprenditorialità e dell’innovazione Richard C. Dorf, Andrew J. Nelson, Roberto Vona Copyright © 2011 – The McGraw-Hill Companies srl 540 APPENDIX B Cases TREXEL We’ve never met a customer who wasn’t interested in our technology. —David Bernstein, CEO of Trexel David Bernstein hung up the phone with Alex d’Arbeloff, Trexel’s largest investor, and contemplated an upcoming Board of Directors meeting scheduled for June 25, 1998. The meeting was only 10 weeks away and Bernstein, Trexel’s president and chief executive officer, needed to present a coherent vision of the company’s new strategy. Bernstein believed that Trexel’s patented technology for manufacturing foamed plastics had the potential to revolutionize much of the worldwide plastics industry. His innovative process technology, known as MuCell, allowed the Woburn, Massachusetts company to produce foamed plastic utilizing 25% to 50% less material than traditional solid plastics without a significant decrease in the strength of the plastic. Bernstein believed the market for products produced via this...
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...You have just witness “bro science” in action. It’s wellintended. It can also be deadly. The difference between 5 grams and 5 micrograms, depending on the substance, can indeed be the difference between life and death. Where should one get such information? From qualified sources, of course. Not from your bro. Want to know about proper dosage? Look in the medical literature and find out what dosages have been shown through experimentation to render the desired effects. Want to know about a proper manufacturing method? Then you need to read technical manuals written by actual engineers. As much as possible, I’ve pointed you to more qualified sources of information than myself throughout this guide. I’ve deliberately left out information about dosages in order to force you to use this as a starting point rather than a definitive resource. At the same time, I’m obviously encouraging DIY experimentation. Allow me to clear up the apparent contradiction. See, I intend for this report to be, among other things, a bit of a shot across the bow of the troubled ship that is the nutritional supplement industry. Here’s a field that can do so much good but that exhibits so little true innovation. When anyone can privatelabel the same substandard supplements everyone else is selling and “win with better marketing,” it doesn’t seem there’s much incentive to raise the bar. The best way to shake up such a market is to educate the buyers. When consumers are aware of...
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