due to them only having a single X chromosome and hemophilia is a recessive x-linked trait. 5. The probability of Marcy and Tom having a child with hemophilia is 12.5%. This is because Marcy has a 50% chance of being a carrier. Marcy’s children in turn have a 50% chance of receiving a copy of the X chromosome. Thus, there is a 25% chance that any of the children would receive a copy of the recessive X allele from Marcy. Tom does not have hemophilia, so we know that the gene on his X chromosome is
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4. Why are none of the males in figure 5.2 shown as carriers of hemophilia? Males cannot carry hemophilia because it is an X-linked disease and males only have a single X chromosome. If the male has an X, he has the disease. 5. What is the probability that Marcy and Tom will have any child with hemophilia (irrespective of sex)? Show how you calculate this. The probability of Marcy and Tom having a child with hemophilia is 12.5%. This is because Marcy has a 50% chance of being a carrier
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possible for a female carrier to have a daughter who has hemophilia? Explain your answer using terms such as sex-linked inheritance, sex-linked genes, dominant, recessive, and X and Y chromosomes. Sex-linked inheritance is when a gene is located on a sex chromosome, usually a mutated gene that can cause a disorder. The sex chromosomes are X and Y. The combination of two sex chromosomes determines a person’s sex. XX is female and XY is male. Hemophilia is a rare, sex-linked inherited blood clotting disorder
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The Battle Against the Royal Disease, Hemophilia A From the beginning of time… Dubbed the “Royal Disease” because Queen Victoria was a carrier, our enemy has been characterized as one of the oldest genetic diseases known to mankind. The earliest records date back to rabbinical writings of the Talmud documented in the second century. A law was present that stated that if two sons of a woman die from circumcision then her third would not be required to be circumcised. This was an illustration
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blindness, Duchenne muscular dystrophy and hemophilia. (O’Neil, 2012). In the case of the recessive mutation that causes hemophilia, a female has to be the carrier of the mutated allele, since she has the X chromosomes only. If the female carrier of the disease mates with a male who has hemophilia (XhY), there would be a one-quarter chance that they would produce a female offspring that has hemophilia (XhXh). Males though are more susceptible to inheriting the hemophilia trait if the mother is a carrier,
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Three cases have been presented to be to review regarding a potential blood disorder: o Amy, a 4-year-old Caucasian female, has been complaining of being tired all the time. She is pale and a picky eater. Her mother is a single mom with a small budget to feed a large family. Amy only eats pasta, breads, and hot dogs, and drinks only artificial fruit punch. Certainly, it is possible that Amy may have symptoms of early childhood diabetes, particularly viewing her diet, but it is likely that
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Genetic diversity is always changing both across space and through time. Typically, the amount and type of genetic diversity within a species vary across its natural range. Additionally, its genetic diversity changes over time. At least in the long-term, and sometimes even over shorter time frames such as a few generations of the species. These natural changes in the genetic diversity of a species create a dynamic landscape upon which any influences that we exert are superimposed. To better understand
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Bubble kid [18]: Nina Graeme was 5 weeks old baby. Her mother, Aga Warnell, observed something wrong with her baby, she wasn't hungry in the way her other daughters had been. Within weeks, Nina became very ill, says her father, Graeme. She was admitted to hospital with a rotavirus infection. Then she picked up pneumonia. In the hospital the doctors revealed a condition called (severe combined immunodeficiency or SCID). She was born with immune system defects due to a genetic defect.
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Effects of the disease can be very minor or extremely fatal. When a person who contains the hemophilia disorder is cut and bleeding they bleed longer than a person who doesn't have hemophilia. As stated before, Hemophilia is a genetic disease that is caused by recessive autosomes, The parents of the infected may not even know they have the disorder because they have no symptoms, these people are called carriers
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Genetically Transmitted Disorders Introduction Genetics originated in the mid-19th century when Gregor Mendel discovered over a ten year period of experimenting with pea plants that certain traits are inherited. His discoveries provided the foundation for the science of genetics. Mendel's findings continue to spur the work and hopes of scientists to uncover the mystery behind how our genes work and what they can reveal to us about the possibility of having certain diseases and conditions
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