CADMIUM POISONING INTRODUCTION and AETIOLOGY Cadmium (Cd) is a naturally occurring toxic metal; it is a group 2b metal that is found between zinc (Zn) and mercury (Hg) on the periodic table, human exposure to Cd occurs primarily by inhalation or ingestion. Cigarette smoking is one of the main sources of human cadmium exposure as kidney and blood Cd levels are usually higher in the kidneys of smokers than that of non-smokers. Smokers have a four or five times higher blood cadmium concentrations
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Microbiology Overview Interpretation of preliminary microbiology data Gram-positive cocci Aerobic In clusters ● Coagulase (+): Staphylococcus aureus ● Coagulase (-): Staphylococcus lugdunensis and other coagulasenegative staphylococci In pairs/chains ● Optochin sensitive: Streptococcus pneumoniae ● Alpha-hemolytic: Viridans group Streptococcus, Enterococcus ● Beta-hemolytic: ○ Group A Strep (Streptococcus pyogenes) ○ Group B Strep (Streptococcus agalactiae) ○ Group C, D, G Strep Anaerobic: Peptostreptococcus
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Aldosterone: Role in Edematous Disorders, Hypertension, Chronic Renal Failure, and Metabolic Syndrome. Schrier RW, Masoumi A, Elhassan E. University of Colorado Denver, Aurora, Colorado. Abstract The role of aldosterone has expanded from the hormone's genomic effects that involve renal sodium transport to nongenomic effects that are independent of the effect of aldosterone on sodium transport. The nongenomic effects of aldosterone to increase fibrosis, collagen deposition, inflammation, and
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Feature Deming’s 14 Principles Background Recent changes in regulatory requirements for clinical trials pose considerable challenges for the clinical research community. The clinical research Quality Assurance (QA) profession as a whole has not historically utilised quality management tools, and QA professionals may have little to no formal training in continuous improvement methods, to be aware of their value in assessing and improving the impact and value of the QA department to any organisation
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evaluated. Hyperlipidemia was induced by passive smoking in a closed chamber having 1 burning ciggrette inside it. The hypolipidemic activity was analysed by reading the blood serum level in UV at 505 nm after treated with reagent present in auto span diagnostic kit. Dose of Methanolic extracts of QI had been prepared by using distilled water i.e. 200 mg/kg p.o. Methanolic extracts of QI significantly reduce the harmful lipid layer in blood serum at varying concentration and dose dependent manner which
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Alzheimer's disease is the most common cause of dementia. Research advances have enabled detailed understanding of the molecular pathogenesis of the hallmarks of the disease-ie, plaques, composed of amyloid β (Aβ), and tangles, composed of hyperphosphorylated tau. However, as our knowledge increases so does our appreciation for the pathogenic complexity of the disorder. Familial Alzheimer's disease is a very rare autosomal dominant disease with early onset, caused by mutations in the amyloid precursor
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Mathematical Biosciences xxx (2011) xxx–xxx Contents lists available at SciVerse ScienceDirect Mathematical Biosciences journal homepage: www.elsevier.com/locate/mbs Observer-based techniques for the identification and analysis of avascular tumor growth Filippo Cacace a, Valerio Cusimano a, Luisa Di Paola a,⇑, Alfredo Germani a,b a b Università Campus Bio-Medico di Roma, via Álvaro del Portillo, 21, 00128 Roma, Italy Dipartimento di Ingegneria Elettrica e dell’Informazione, Università
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I. 진단혈액 진단혈액 수련항목 (1) : 혈액학적검사 기본 술기 표준수련기간 : 1주 수련내용 : ◆ 용어정의 : • 혈액학적검사 : 혈액세포와 응고에 관련된 일련의 검사를 의미한다. 혈구의 체내분포, 구조, 기능에 관련된 검사, 골수에 분포하는 전구세포에 관한 검사, 혈구에 영향을 끼칠 수 있는 혈장 인자에 관한 검사 및 유전자 이상에 관련된 검사 등을 포괄적으로 포함한다. • 망상적혈구수 : 적혈구 성숙 단계 중 정염색성 적아구(orthochromatophilic normoblast) 바로 다음 단계의 세포로 핵이 빠져나간 직후부터를 의미한다. 미토콘드리아, 중심소체(centriole), 리보솜 등을 함유하고 있으며 말초혈액에서 24-48시간의 성숙과정을 거쳐서 성숙한 적혈구로 된다 (Ref. Williams 16th p373-374) ◆ 숙지할 필수 지식 : • 혈액학 검사에 사용되는 검체와 항응고제의 작용기전 및 종류
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Describe the structure-function relationships of human IgG and how might such an understanding influence the choice of IgG subclass in potential antibody-based therapies? Our body is under constant attack whether from external with viruses, bacteria and parasites or from the internal; with the development of tumour cells in cancer. We have a number of ways to prevent organisms from entering our body and surviving. This includes our skin, mucous membranes and the low pH of our stomach acids. However
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Rheumatoid Arthritis A Review of The Literature Mechanisms of Human Pathology Charles Childers Rheumatoid Arthritis Rheumatoid Arthritis (RA) is a chronic, autoimmune systemic inflammatory process that primarily attacks synovial joints as well as other tissues and organs of the body. This disorder is characterized by hyperplasia of synovial cells leading to an inflammatory response of the synovium that may ultimately cause destruction of articular cartilage. In cases
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