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Activity in Science

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Submitted By vngieeline
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Group no. Date: Score:

Activity no. __
What’s the Message
I. Objectives:
• Make a model to show how the order of bases in DNA determines the order of bases in mRNA.
• Infer why the structure of DNA enables it to be easily copied.
II. Materials:

• crayons
• 1/4 illustration board or long folder
• scissors
• paste/tape

III. Procedure:
1. Use the patterns of the components of the DNA provided by your teacher. Color code phosphate = blue, deoxyribose sugar = green, ribose sugar = brown and nitrogenous bases as follows: adenine = yellow, thymine = pink, guanine = violet and cytosine = red and uracil= orange.
2. Cut out the shapes of each nucleotide.
3. Using the given order of the nucleotides below, construct a double stranded DNA molecule.

Guanine
Adenine
Cytosine
Thymine
Cytosine
Guanine

4. Fasten your molecule together using a clear tape. Do not tape across base pairs.
5. Step 1, use the patterns of the components of the RNA provided by your teacher. Color code phosphate = blue, ribose sugar = brown and nitrogenous bases as follows: adenine = yellow, uracil = orange, guanine = violet and cytosine = red.6. Cut out the shapes of each nucleotide.
7. With your DNA model in front of you, demonstrate the process of transcription by first pulling the DNA model apart between the base pairs.
8. Using the right strand of the DNA model in step 3, begin matching complementary RNA nucleotides with the exposed bases on the DNA model to make mRNA.9. Tape the RNA nucleotides.
10. When you are finished, tape your new mRNA molecule together.
IV. Analysis
Q1. Does the mRNA model more closely resemble the DNA strand from which it was transcribed?

Q2. Explain how the structure of DNA enables the molecule to be easily transcribed. Why is this important for genetic information?

Q3. Why is RNA

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