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Ap1 Osteoporosis

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Osteoporosis

Osteoporosis is a common bone disease that decreases bone mass and density which causes the bones to become weak and brittle, more likely to fracture. In osteoporosis, the bone mineral density (BMD) is reduced, bone structure deteriorates, and proteins in bone are altered. Osteoporosis occurs when the body fails to form enough new bone, when too much existing bone is reabsorbed by the body, or both.
The most common cause of osteoporosis is genetics. Some people inherit the risk from their parents. Other risks include not having enough calcium to build new bone tissue. Calcium is one of the important minerals needed by your body for bones to form. If your body doesn’t get enough calcium and vitamin D, or doesn’t absorb enough calcium from your diet, your bones may become brittle and likely to fracture. Smoking and childhood diseases are also risk factors.
The disease may be classified as primary type 1, primary type 2, or secondary. Osteoporosis most common in women after menopause is referred to as primary type 1 or postmenopausal osteoporosis, which is attributable to the decrease in estrogen production after menopause. Primary type 2 osteoporosis or senile osteoporosis occurs after age 75 and is seen in both females and males. Secondary osteoporosis may arise at any age and affect men and women. This comes from chronic medical problems or disease, or prolonged use of medications such as glucocorticoids.
There are many ways to diagnose osteoporosis. The most common osteoporosis test is dual X-ray absorptiometry which is also called DXA or DEXA. It measures the bone density in the hip and spine. The results for this test is called T-scores. A normal score is between 0 and -1.0. With osteoporosis the score will be lower than -2.5. Chemical Biomarker are useful in detecting bone degeneration. Blood and urine test check the metabolism of the bones.

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