...Estimation of diabetic retinopathy with artery/vein classification in retinal images using Artificial Neural Network Leshmi Satheesh M.Tech Student,Dept. of Electronics & Communication Mohandas College of Engineering, Kerala University Trivandrum-695541, Kerala, India Email: leshmi24@gmail.com Abstract—Diabetic retinopathy is the single largest explanation for sight loss and visual impairment in eighteen to sixty five year olds . Damage of blood vessels in the eye and the formation of lesions in the retina are the earliest signs of diabetic retinopathy. Efficient image processing and analysis algorithms have to be developed for the automated screening programs to work robustly and effectively. For the detection of vascular changes...
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...Diabetics Case Study Diabetes is of high incidence in the United States affecting children and adults of different ethnics groups and levels of education. Today we will discuss Diabetes, management, factors that interfere with its Control and the complication. The challenges of Mr. Reyes diabetes control and how this affects the family. Education to the public on prevention of diabetes by weight management and exercise is Imperative at an early age. Diabetes is a manageable disease which we can learn to live with it in order to control it. According to the ADA, nearly 26 million children and adults are living with diabetes, and another 79 million are at high risk for developing type 2 diabetes; even more alarming data suggests that by 2050, as many as one in three American adults will develop diabetes (“Cabot Creamery Cooperative Offers 5-Day Menu Planner for American Diabetes Month,” 2011, Para 1.). According to the CDC, the United States incurred an estimated $174 billion in direct and indirect medical costs related to diabetes in 2007(“Diabetes: Affects 25.8 million,” 2011, P. 26). "These statistics paint a disturbing picture for Americans in the near future," said Cabot Registered Dietitian Regan Jones, "but fortunately, there is still time to act. (“Cabot Creamery Cooperative Offers 5-Day Menu Planner for American Diabetes Month,” 2011, Para 2.). Education and a responsible diet may prevent some instances of type 2 diabetes from ever occurring, and for those already...
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...diabetes mellitus. Diabetic retinopathy is one of the leading causes of irreversible blindness in the United States. This retinopathy can occur with either type 1 or type 2 diabetes mellitus and the development depends on the duration of the disease. Most persons with type 1 diabetes and many of those with type-2 diabetes develop some background (non-proliferative) retinopathy. Proliferative retinopathy is more dangerous and is more likely to occur in poorly controlled diabetes. 3.3.1 Pathophysiology: The uptake of glucose by the synthesis of the body is mediated by the Insulin-like growth factor 1 (IGF-1). An insentivity of glucose uptake receptors to insulin and absence of insulin result in increased...
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...unaware they have the condition and it can lead to long-term complications including eye problems, kidney disease, foot ulcers and cardiovascular disease. Gregg et al (2005), states advances in preventative medicine have seen an effective reduction in the burden of risk from hypertension and hyperlipidaemia but the incidence of diabetes has continued to rise, driving cardiovascular rates. There has been much done in recent years to identify people who are at high risk of developing diabetes. This assignment will discuss the link between diabetes, obesity and cardiovascular disease. It will also identify lifestyle and behaviour changes involving the multi-disciplinary team and structured patient education of diabetics. The case study for this assignment is Mrs Smith, newly diagnosed with type 2 diabetes and a family history of heart disease and diabetes. She leads a sedentary lifestyle, is overweight and has a poor diet (see appendix). The Health Survey for England (2006), state both obesity and low levels of physical activity are associated...
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...both.[1] Out of all cases of diabetes, Type 1 diabetes represents 5% to 10%. Its risk factors include autoimmune, genetic, and environmental factors. To be honest, there are no known approaches to prevent type 1 diabetes. The other 90% to 95% of all diagnosed diabetes cases is represented by Type 2 diabetes. This form of diabetes usually happens when the body is unable to produce enough insulin to address the resistance. The pancreas may reduce the production of insulin or eventually stop producing it.[2] In spite of the fact that the pathogenesis...
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...Case study 76 Endocrine Disorders 1. Interpret Y.L.'s laboratory results • HbA1C is elevated at 8.8% and the goal for diabetics is to keep that value below 7% Hemoglobin A1c. Her number is concerning because it indicates that her blood sugar has been way too high over the past few months. The A1c is an indication of glycosylation in the body which is damaging to the blood vessels and peripheral nerves. It causes thickening of the basement membrane which will impair oxygen transport to the tissues and carbon dioxide removal. • High BP • Total Cholesterol is elevated at 256mg/dL, normal value is below 200mg/dL • Fasting glucose is high at 184mg/dL, normal value is below 126mg/dL • Triglycerides are elevated at 346 mg/dL, normal levels are below 150mg/dL. Y.L. indicates levels that are high. • LDL levels are elevated at 155mg/dL and ideal values are below 100mg/dL; LDL is the value you want to be the lowest. • HDL levels are low and the HDL levels need to be high, 40-60mg/dL is desired. • Urine Analysis indicates that Y.L. is spilling glucose into her urine. 2. Identify the three methods used to diagnose DM. - Fasting blood glucose of > 126 mg/dl - Random Glucose Level >200 mg/dl (plus presence of other symptoms) - A1C > 6.5% 3. Identify three functions of insulin. • regulates glucose metabolism • stimulates lipogenesis • stimulates growth 4. Describe the major pathophysiologic difference between type 1 and type 2 DM. • Type 1 diabetes,...
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...[pic] Resolution of the World Health Organization After meeting in Geneva in May 2003 for the Fifty-Sixth World Health Assembly, the WHO outlined its Global Initiative for the Elimination of Avoidable Blindness, or VISION 2020 plan. The WHO urges national governments to: • Set up, not later than 2005, a national VISION 2020 plan, in partnership with the WHO and in collaboration with NGOs and the private sector. • Establish a national coordinating committee for VISION 2020 or a national blindness prevention committee, which may include consumer or patient groups, to develop and implement the plan. • Commence implementation of such plans by 2007 at the latest. • Include effective information systems with standardized indicators and periodic monitoring and evaluation, with the aim of showing a reduction in the magnitude of avoidable blindness by 2010. • Mobilize resources for eliminating avoidable blindness. In turn, the WHO agrees to: • Maintain and strengthen the WHO’s collaboration with governments and all partners of the initiative. • Ensure coordination of the implementation of the VISION 2020 plan, by setting up a monitoring committee grouping all those involved, including national government representatives. • Provide support for strengthening national capability, especially through development of human resources, to coordinate, assess, and prevent avoidable blindness...
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...reach to 552 million people by 2030 (Murea, Ma, & Freedman, 2012). Type 2 diabetes accounts for 90% of all diabetic cases. People with diabetes have a 25-75% high risk of death associated with cancer, infection, liver disease, lung disease, and falls (Murea, Ma, & Freedman, 2012). Type 2 diabetes is characterized by high blood sugar, impairment in insulin secretion, and insulin resistance (McCulloch & Roberston, 2017). According to McCulloch and Robertson (2017), our ability to prevent this type of diabetes in the...
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...problems and blindness, and pregnancy. Diabetes is the seventh leading cause of death within the United States. This growing trend is preventable by increasing awareness about the risk of diabetes and educating people on the importance of choosing a lifestyle consisting a healthy diet and physical activity. Type 2 Diabetes - Reducing the Risk Obesity within the United States has reached epidemic proportions within the past several decades. Obesity is a leading cause of preventable death in the United States, causing an estimated 200,000 deaths per year (2013). Obesity is a major contributing factor to the increasing number of people of have type 2 diabetes. The resulting medical costs are overwhelming and easily preventable in most cases. Lifestyle factors, such as diet and physical activity play a major role in the prevention and treatment of type 2 diabetes. Type 2 Diabetes: Definition Insulin resistance can lead to type 2 diabetes over time if not addressed early. In insulin resistance, the body’s cells don’t respond properly to the insulin produced by the pancreas, thus aren’t able to easily absorb glucose from the bloodstream. Over time, glucose builds up in the blood stream and the pancreas can’t produce enough insulin to keep up...
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...Diabetes Case Study NUR/427 January 13, 2011 Diabetes Case Study Diabetes mellitus (DM) is a chronic disease that affects millions of people across the nation. According to LeMone and Burke (2008), “Approximately 1.3 million new cases of DM are diagnosed each year in the United States” (pg 563). The Centers for Disease Control and Prevention estimate that 23.6 million people in the United States have DM. Collectively 17.9 million people were diagnosed and 5.7 million people were undiagnosed with DM in the year 2007. Of all the documented cases 90-95 percent have type II DM and the remaining 5-10 percent have type I DM (Centers for Disease Control and Prevention, 2008). In the United States DM is the sixth most leading cause of death by a disease. Deaths are commonly caused by the cardiovascular effects associated with DM that result in coronary artery disease, atherosclerosis, and stroke. People diagnosed with DM are two to four times more likely to have heart disease or have a stroke than people who are not diabetic. DM is the leading cause of end-stage renal disease in the United States. DM is also the most common cause of nontraumatic amputations and newly diagnosed blindness (LeMone & Burke, 2008). Signs and Symptoms Before someone is diagnosed with DM he or she usually experiences common signs and symptoms of the disease that leads him or her to see a physician. In type I DM the signs and symptoms that commonly present are the result of hyperglycemia. According...
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...healthcare providers to assess the blood glucose concentration. The WHO and ADA (2010) has also associated the HbA1c as the major test for diagnosing diabetes. Jazminder is doubtful that she might develop diabetes because her sister has developed recently. However, apparently there is no symptom for the presence of diabetes in diabetes. According to Saudek et al (2008), asymptomatic people may be at the higher risk of developing diabetes. In particular, for people ≥45 years of age, the screening is necessary. Jazminder must be evaluated for HbA1c, 2-h OGTT, and FPG to get appropriate results. It has been recommended by the IDF that it relies over the healthcare provider to decide which screening must essentially be done for respective patient cases. However, the FPG remains the test suggested in almost every condition. Besides, the ADA and International Expert Committee has favored the HbA1c for assessment of diabetes. According to Sacks et al (2009), if the results of FPG is <5.6 mmol/L (100 mg/dL), the patient must be tested for every three years interval. Likewise, the normal but cautionary ranges for 2-h plasma glucose concentration is <7.8 mmol/L (140 mg/dL). These results indicate that...
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...Dependent Diabetes Mallitus or Adult Onset Diabets. This disease results due to a defect in the functioning of insulin in the body. It can either be in a form of insulin deficiency, or insulin resistance. Type II diabetes mallitus is a familial disease in some cases where it runs in families. In such cases, it is most commonly a result of weight gain. Obesity is a major risk factor for type II diabetes mallitus in those persons in whom there is a strong family history of diabetes. Normally, the blood glucose levels higher than 200 mg/dl are considered to be alarming and require confirmatory tests for diagnosis. Type 2 diabetes 3 CAUSES: Type II diabetes mallitus can either be a result of: 1. Insulin deficiency or 2. Insulin resistance. Insulin is basically required for metabolism of the blood glucose, When metabolised by insulin, the glucose is moved to its storage places in the cells and thus used as required. Insulin is produced by the islets of Langerhan’s in the pancreas. A defect in these cells results in a deficiency of insulin. Insulin resistance results due to a resistance offered by the target cells to the effects of insulin. In such cases, insulin is not deficient, instead the target tissues, like the fat, liver and muscle cells fail to respond to insulin; this also results in greater levels of blood glucose, leading to diabetes, as glucose is not stored in these cells. Type II diabetes mallitus...
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...THE AQUEOUS EXTRACT OF MUNTINGIA CALABURA LINN. ON THE BLOOD GLUCOSE LEVELS OF INDUCED DIABETIC MICE AT FASTED STATE Research Proposal C-2 Lim, Phoebe Lim, Syndel Lipana, Kirk Liu, Johanna Llamas, Alay Llego, Nasreen Lopez, Camille Lopez-Dee, Bernadette Lorenzo, Adrian Lorilla, Richardson Lu, Pei-Chei Lucila, Ana Marie Lustre, Alexis Lorenz Macabagdal, Jesmarie Macalma, Glenn Macapagal, Justin Madrid, Bianca Malabanan, Michelle Malaca, Chester Mallari, Romina Malvar, Alfred Mamauag, Mary Jo CHAPTER I INTRODUCTION BACKGROUND OF THE STUDY Diabetes mellitus is the most common metabolic disorder, its prevalence varying widely worldwide (Takrouri, 2009). The frequency of the diabetes escalate worldwide, with a major impact on the population of developing countries (Park's textbook of preventive and social medicine. 15th edition, 1997). (I ERASED THE USA PART I JUST FOCUSED IN THE PHILIPPINES) In the Philippines, diabetes ranked 8th in the leading causes of mortality (Department of Health, 2005). As many as 1.4 million Filipino adults (aged 20 and above) acquired diabetes in the last five years mainly because of unhealthy diets and sedentary lifestyles, according to data compiled by anti-diabetes advocates. It has been proven that the prevalence of diabetes is constantly on the rise (Takrouri, 2009). According to a study made by Wild et al, the total number of people with diabetes is projected to rise from 171...
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...Conditions Related to the Eye and Blindness Michael A. Allen Jackson State University Abstract Conditions related to the eye and blindness is very common. There are many disease of the eye. Many of these diseases can cause a lot of harm. There are five main points that will be discussed they are age-related macular degeneration, retinitis pigmentosa, retinopathy, visual impairment in higher learning, and social support for the visually impaired. Macular degeneration often damages central vision and is prevalent in people age 60 and over with rare cases of people fewer than 50. Retinitis Pigmentosa is common among families; it’s not always related to hereditary factors. Retinopathy is a common problem for people with diabetes where retinal blood vessels break down and affect vision. People with visual impairments who are in higher learning are very common now days and accommodations are set up for persons. Social support for people who are visually impaired is key factors to helping those individuals have a normal and productive life. Introduction There are many eye conditions. They are listed as followed. Lazy Eye or Amblyopia is a very common condition. Usually present early in childhood, lazy eye can be corrected if caught early. Learn what you can do to correct this eye condition before it becomes severe. Aphakia is a condition where the lens of the eye is missing. It can greatly decrease your vision acuity and cause other problems if not treated. Astigmatism...
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...Diabetes Case Study Diana Gallardo, Karen Joy, Brianna Herrera, Svetlana Knyazeva NUR/427 5/6/2013 Sara Gerrie RN, MSN, CPNP Diabetes Mellitus is a chronic illness affecting the metabolic and endocrine function of the body. Type 1 diabetes affects 5% to 10% of people with the disease, whereas type 2 diabetes affects nearly 90% to 95% of people with the disease (Centers for Disease Control and Prevention [CDC], 2008). An overview of the incidence of diabetes in the United States, signs and symptoms, and effects of diabetes as a chronic disease will be provided. The case study of Angelo Reyes, a 40-year-old White male living with type 1 diabetes will be used to implement teaching requirements with measurable learning objectives from Bloom’s taxonomy of learning domains. The psychosocial challenges that Angelo Reyes encounters will also be discussed. According to Smeltzer, Bare, Hinkle, and Cheever (2010), the number of people with diabetes in the United States is 23 million with increasing rates of 1 million new diagnosed cases per year. This number is expected to exceed 30 million by 2030 (CDC, 2008). People older than 65 years old seem to have more intolerance to glucose and 40% of them account for the population with diabetes. Minority groups such as African Americans, Native Americans, Hispanics, Asian Americans, and Pacific Islanders are at higher risk for diabetes, complications associated with the disease, and high rates of disease related death (CDC, 2008)...
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