...DNA Worksheet REVISED Part1: Basic structure of DNA The nucleotide bases of a DNA consists of specific codes and particular strands of this codes are known as the genes. The genes codes for a particular protein which eventually be a specific trait. The pairing of the base in a DNA molecule is very specific. Adenine usually pairs with Thymine while Guanine normally pairs with Cytosine. A segment of a gene from DNA usually gives the necessary directions to build a RNA molecule and eventually translated into a protein (Simon, Reece and Dickey, 2010). Reason why DNA is referred to as a protein recipe DNA is referred to as a protein recipe because its molecules are made up of amino acid proteins which are in form of a long strand. The DNA structure is composed of codons. Basically, the DNA codes for RNA codon or a transcription which is used to form proteins which is the translation of the codon. Each group of tri-codons are then read by the ribosomes where for each group of 3 such codons, there is an amino acid. These amino acids are then bound together to make a protein chain. The complexity of a protein depends on the number and type of chains (Simon, Reece and Dickey, 2010). Part 2: Differences between DNA and RNA DNA is used for long-term storage of genetic information, transmission of genetic information so as to make other cells and new organisms and to transfer the genetic code to the ribosomes from the nucleus to manufacture proteins. On the other hand, RNA is used...
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...head: SIGNIFICANCE OF DNA Significance of DNA Significance of DNA Deoxyribonucleic acid (DNA) was first discovered in 1869 by Johann Friedrich Miescher, but it was not until the 1950s while studying viral replication did Alfred Hershey and Martha Chase determine DNA was Genetic material. In 1953 James Watson and Francis Crick discovered DNA was a double helix (a double helix looks like a twisted ladder). The discovery of Watson and Crick opened the door helping describe the significance and importance of DNA as the molecule of inheritance while addressing the structure of the DNA molecule, and why is a molecule of DNA so perfect for the job it performs. I will look at what exactly does DNA code for, how is that translated into actual traits, what are mitosis and meiosis, what are the similarities and differences, and what do mitosis and meiosis allow for. I will show how traits are passed from parents to offspring and lastly describe how knowledge of DNA and genetics can help in my life. The Significance and Importance of deoxyribonucleic Acid (DNA) as the Molecule of Inheritance The significance and importance of DNA “is the body’s instruction manual for making you who you are. It is present in any living being. It carries all the instructions and materials the body needs to function”(Leving, 2008). The DNA in cells is all the same for individuals, which create a specific identity for each individual. Discuss Briefly the structure of the DNA Molecule and Why is...
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...Comparison chart | DNA | RNA | Definition: | A nucleic acid that contains the genetic instructions used in the development and functioning of all known living organisms | RNA, single-stranded chain of alternating phosphate and ribose units with the bases adenine, guanine, cytosine, and uracil bonded to the ribose. RNA molecules are involved in protein synthesis and sometimes in the transmission of genetic information. | Job/Role: | Medium of long-term storage and transmission of genetic information | The main job of RNA is to transfer the genetic code need for the creation of proteins from the nucleus to the ribosome. this process prevents the DNA from having to leave the nucleus, so it stays safe. Without RNA, proteins could never be made. | Stands for: | DeoxyriboNucleicAcid | RiboNucleicAcid | Predominant Structure: | Typically a double- stranded molecule with a long chain of nucleotides | A single-stranded molecule in most of its biological roles and has a shorter chain of nucleotides | Pairing of Bases: | A-T(Adenine-Thymine), G-C(Guanine-Cytosine) | A-U(Adenine-Uracil), G-C(Guanine-Cytosine) | Stability: | Deoxyribose sugar in DNA is less reactive because of C-H bonds. Stable in alkaline conditions. DNA has smaller grooves where the damaging enzyme can attach which makes it harder for the enzyme to attack DNA. | Ribose sugar is more reactive because of C-OH (hydroxyl) bonds. Not stable in alkaline conditions. RNA on the other hand has larger grooves which...
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...difference between the cell cycles of a normal and cancerous cell is that the cancerous cell is uncontrolled when it reaches the cell division or anything else goes wrong threwout the cycle(can be very dangerous) and the normal cell is controlled throughout the whole cycle. In the g1 phase, the cell synthesizes mRNA and proteins in preparation for subsequent steps leading to mitosis. When the cell reaches the end of the G1 phase it is controlled at a checkpoint called G1/S, G1/S is when the cell decides whether or not to replicate its DNA. At the checkpoint the cell is checked for DNA. Cells with no damaged DNA (normal cells) continue to S phase, in S phase cells with damaged DNA (cancerous cells) that cannot be repaired die. G2 is when cell is about to divide. the M is...
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...Associate Program Material DNA Worksheet Answer the following in at least 100 words: 1. Describe the structure of DNA. DNA nucleotide bases consist of a particular code and specific strands of this code are termed genes. A gene will code for particular proteins which will end in a specific trait. The base pairing in a DNA molecule is specific: Adenine always pairs with Thymine and Guanine always pairs with Cytosine. A gene segment from DNA will give the directions necessary to build a RNA molecule which finally can be translated into a protein. 2. How does an organism’s genotype determine its phenotype? An organism's genotype is its specific combination of alleles for a given gene and the phenotype is the physical indication of an organism's allelic combination. A trait is the acquired or inherited characteristics shown in a phenotype. * 3. Describe each stage of the flow of information starting with DNA and ending with a trait. * A sequential set of nucleotides in the DNA are transcribed into a molecule of RNA in the cell’s nucleus. Translation of the RNA into a specific amino acid sequence of a protein occurs after the RNA travels to the cytoplasm. “The molecular “chain of command” is from DNA in the nucleus to RNA to protein synthesis in the cytoplasm. The two main stages are transcription, the transfer of genetic information from DNA into an RNA molecule, and translation, the transfer of the information from RNA into a protein...
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...significant contribution to, and quotation in this report that I have taken from the work (s) of other people has been attributed, and has been cited and referenced. 3. This report is my own. 4. I have not allowed, and will not allow anyone to copy my work with the intention of passing it off as his/her own work. Signature date Question: Discuss what are the nucleotides and nucleic acids in human health and disease Almost all living cells contain two very important substances, deoxyribonucleic acid or DNA and ribonucleic acid or RNA. These molecules carry instructions for making proteins. The help specify the amino acid sequence and thus which proteins will be made. When nucleotides join together they form the functional units of the structure of DNA and RNA where DNA contains one less hydroxyl group than RNA. Nucleotides serve as a source of energy therefore playing an important role in metabolism, for example mitochondria produce ATP or Adenosine triphosphate. They also serve as co-factors in enzymatic reactions and participate in cell signalling for example as Camp messengers. A single nucleotide is made up of three smaller molecules, a phosphate group which helps to form the sugar phosphate backbone via phosphodiester bonds which is between the three carbon sugar of one atom and the four carbon sugar of another, a pentose sugar, deoxyribose or ribose, and a nitrogenous...
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...Activity no. __ What’s the Message I. Objectives: • Make a model to show how the order of bases in DNA determines the order of bases in mRNA. • Infer why the structure of DNA enables it to be easily copied. II. Materials: • crayons • 1/4 illustration board or long folder • scissors • paste/tape III. Procedure: 1. Use the patterns of the components of the DNA provided by your teacher. Color code phosphate = blue, deoxyribose sugar = green, ribose sugar = brown and nitrogenous bases as follows: adenine = yellow, thymine = pink, guanine = violet and cytosine = red and uracil= orange. 2. Cut out the shapes of each nucleotide. 3. Using the given order of the nucleotides below, construct a double stranded DNA molecule. Guanine Adenine Cytosine Thymine Cytosine Guanine 4. Fasten your molecule together using a clear tape. Do not tape across base pairs. 5. Step 1, use the patterns of the components of the RNA provided by your teacher. Color code phosphate = blue, ribose sugar = brown and nitrogenous bases as follows: adenine = yellow, uracil = orange, guanine = violet and cytosine = red.6. Cut out the shapes of each nucleotide. 7. With your DNA model in front of you, demonstrate the process of transcription by first pulling the DNA model apart between the base pairs. 8. Using the right strand of the DNA model in step 3, begin matching complementary RNA nucleotides with the exposed bases on the DNA model to make mRNA.9. Tape the RNA nucleotides. 10. When you are finished, tape your new mRNA...
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...separate sheet of paper and submit it to Dropbox 1 by midnight Central Time on Sunday. 1. What is the genetic material of organisms? 2. What are the requirements for DNA to be the genetic material? 3. Who can be credited with determining that DNA is the genetic material of living things? 4. What nucleotides are contained in DNA? 5. What is the difference between pyrimidine and purine bases? 6. State Chargaff’s rules. 7. What is the estimate of the number of base pairs on each human chromosome? 8. Describe the Watson-Crick model for DNA. 9. Explain the meaning of complementary base pairings. 10. What enzyme is required for DNA replication? 11. What molecules form the backbone of a DNA molecule? 12. What type of molecules does the genetic code in DNA produce? 13. Identify three differences between DNA and RNA. 14. What is the role of mRNA? 15. What is transcription? 16. What is translation? 17. What does it mean to say the genetic code is unambiguous? 18. What role is performed by transfer RNA? 19. If a DNA strand is represented by the bases: A-C-T-G-G-C what are the bases that will be included in the replicated strand? 20. If a DNA strand is A-C-T-G-G-C, what is the base representation that will be produced by transcription? 21. If a messenger RNA molecule is U-C-A-A-C-G what will be the tRNA molecule...
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...The genetic information is stored in the DNA which is a chemical structure which has two backbone which form a spiral around each other so that it is held in place also it has 4 bases which are adenine, thymine, cytosine and guanine(1). There are also bridges across the bases which are hydrogen bonds which hold the base pairings together. The sequences of the 4 bases are the genetic information for making any substance in the body, the variability within these codes which makes who we are and different to another person is the variation of the coding of the bases (1). Task 3: The DNA stores all of the information for protein synthesis and the RNA carries out the instructions which are encoded in the DNA most of the body activities are carried out by proteins, and for the protein to be correct the sequence of the amino acid has to be therefore right. There are three kinds of RNA molecules which carry out different functions in the process of protein synthesis. One type is messenger RNA which carries the genetic information from the DNA in the form of 3 base code which the codes for an amino acid. The second is transfer RNA which is essential when deciphering the code from the mRNA so an amino acid has it won different tRNA which binds to it and takes it to the mRNA when it needs it, the correct tRNA attaches to the amino acid and is selected at each step because the Trna has 3 base sequence that can only pair with the complementary code on the mRNA. The last is ribosomal RNA which...
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...DNA DNA or Deoxyribonucleic acid is the very building block needed in the creation of life. It is composed of genetic instruction to map out the creation of an entire organism. DNA is well suited in the storage of biological information. Yet with all of this complex information there are certain chemicals or forms of energy that can damage or alter this special coding. In process of damaging or altering the coding of DNA the most dreaded situation of a cancerous cell can be formed. To start let’s look at the different kinds of radiation that may or may not effect DNA. Alpha, Beta, and Gamma Radiation Ionizing Radiation can change the way our body’s work and develop. Direct includes covalent linkage between nitrogenous bases, and creating structure like thymine dimmers. Indirect is when it interacts with water to create free radicals which can interact with a person’s DNA. It can cause single or double stranded breaks in the sugar- phosphate backbone. (Buttons, n.d.) Alpha Radiation is a process that needs to be swallowed, inhaled, and or absorbed into the blood stream. This can increase the risk of cancer also known as lung cancer. Radon is a silent but deadly killer. To determine if one has been affected by alpha particles testing would be completed with special equipment and gear to prevent those from any exposure. Beta Particles can be a helpful process of treatment to many, such as treating thyroid disorders, cancer, and Graves’ disease (hyperthyroidism). It also...
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...DNA vs. RNA Dustin D. Napier Computer Science Degree Grantham University DNA vs. RNA DNA stands for deoxyribonucleic acid, while RNA is ribonucleic acid. DNA is a double strand and RNA is a single strand. Although DNA and RNA both carry genetic information, there are quite a few differences between them. The following information will describe the differences between DNA and RNA DNA DNA contains long-term storage of genetic information; transmission of genetic information to make other cells and new organisms. DNA is a double strand that has a long chain of nucleotides. DNA has a composition of bases and sugars. They are deoxyribose sugar, phosphate backbone, adenine, guanine, cytosine, thymine bases. DNA is also self-replicating. DNA has adenine-thymine also known as AT and guanine-cytosine also known as GC. DNA has a bond that make it very stable. The bond is a C-H bond. DNA has small grooves that serve as protection and minimal space for enzymes to attach to the strand its self. DNA is vulnerable to Ultraviolet that would cause damage to the strand. RNA RNA transfers the genetic code from the nucleus to the ribosome and that produces proteins. RNA transfers genetic information in some specimens. RNA in some cases is what molecule was used to store genetic blue prints in prime organisms. RNA is a single strand and the helix consists of short chains of nucleotides. RNA has a composition of bases and sugars. They are ribose sugar, phosphate backbone, adenine, guanine...
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...Importance of DNA - A T2 Assessment Understanding what DNA is, is very important. DNA is the material that carries all the information about how a human will look (facial features, etc,.) and also how they will process daily. For example, DNA in humans determines things such as what color the eyes are, what color the hair is, and also what gender you are when a baby. DNA is found in the nucleus of almost all cells. DNA also does something called replicating nucleotides. If DNA never replicated, cell life would be impossible. If this really were to happen, the cells would then die. DNA replicates itself in order to create more DNA strands for cells. It happens along the entire DNA molecule. It continues this until the entire strand/ladder...
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...it is their genes and shows what they look like and how they act. Biological traits are stored in DNA and can be passed on to successive generations through meiosis, which increases genetic variability. DNA stores and transmits genetic information to the next generation. The structure of DNA is double stacked and double helix. Genetic information is stored is stored in DNA chromosomes in 23 pairs. DNA transmits information to the next generation through cellular division. Meiosis increases reproductive variability through crossing-over. Meiosis is the reproduction of gametes (sex cells). Crossing-over is the exchange of chromosomal segments between a pair of homologous chromosomes during prophase I of meiosis. Crossing-over helps variability in cells because it makes the cell different and more adaptable to new or different environments. DNA alternations such as insertions, deletions, and substitutions can cause the appearance of new traits. Insertions are pieces or a piece of DNA copied too many times. Deletions are pieces or a piece of DNA code for one gene is lost. Substitutions change one base for another. These 3 alternations cause new traits to appear by making too many or not enough DNA. Sexual reproduction and asexual reproduction both have advantages and disadvantages. 2 advantages of sexual reproduction are that the offspring is not identical in looks and DNA. Another advantage is that the offspring is more adaptable to different climates and/or resources...
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... Chapter 1 provides a glimpse of the basic concepts of genetics and genomics, and offers examples of DNA information impacting daily life. In this new era of genomics, individuals have access to their own genetic information, and health care providers are learning how to incorporate DNA data into diagnostic and therapeutic medicine. Bioethics deals with issues of privacy, discrimination, and justice that arise from use and misuse of genetic information. DNA, genes, chromosomes, and genomes are the levels of genetic information, and they impact biology at the cell, tissue, organ, individual, family, and population levels. Genes encode proteins, and the exome is the small part of the genome that does so. Most traits arise from interactions of genes and environmental factors. Genetic information is in health care to identify individuals, in investigating the environment, and in understanding evolution. CHAPTER OUTLINE 1.1 Introducing Genes and Genomes 1. Genetics is a branch of biology concerned with inherited traits and their variation, and how these traits are passed from one generation to the next (heredity). 2. With continuing analysis of human genome sequences, human genetics has grown from a largely academic science to touch many areas of medicine, with practical and societal implications. 3. Genes are the unit of inheritance and are composed of DNA. 4. An organism’s genome is its complete set of genetic information. 5. Genomics is a field of study that...
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...Molecular biology is the study of genes and the specific details that regulate the transcription and translation of DNA, from generation to generation. This type of biology allows biotechnology to use this knowledge in order to manipulate organisms’ DNA to help solve human issues including overcoming diseases and physical handicaps. Biotechnology has made breakthroughs in various nucleic acid and protein studies, and it has given scientists the ability to comprehend the complicated construction of DNA. Understanding the blueprints of DNA and how it is translated into proteins gives chemists the opportunity to define features like a genome, which is an organism’s complete set of DNA. Our DNA is important because it is our hereditary code, and that is what controls our appearance, behavior, and tendencies....
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