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Ectodermal Dysplasia Research Paper

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All humans reproduce the same way, but develop differently.Genetic disorders can be very fatal to some human beings. As the body gets ready to form a baby in a mother's womb,genetic disorders can occur.

Melanie Gaydos,an actress and model from New York,suffers from the genetic condition called Ectodermal Dysplasia. A group with different heretical disorders that affect the ectoderm,a layer of tissue that contributes to the formation of the skin,hair,nails,teeth,and sweat glands. However,this condition can be passed on from affected people to their children. Ectodermal dysplasia is caused by mutations in various genes;the mutations may be inherited from a parent, or normal genes may become mutated at the time of egg or sperm formation,or after fertilization. Most are caused by mutations in the EDA gene,a gene that provides instructions for making proteins,which is part of a signaling pathway that plays an important role in developing before birth;however,it is inherited in an X-linked recessive pattern. Some of the symptoms of Ectodermal Dysplasia include: Abnormal nails,missing teeth,and decreased tears and skin color pigment. …show more content…
A congenital condition in which the major visceral organs are reversed or mirrored from their normal conditions. Situs Inversus is caused by an autosomal recessive genetic condition. An unaffected carrier mother and an unaffected carrier father have 1 in 4 chance in having a child with Situs Inversus. The primitive loop in the embryo moves into the reverse direction of its normal position during the fetal development,causing displacement of organs. It is possible that some humans don't experience complications,but some can experience cardiac dysfunction or primary ciliary

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Ectodermal Dysplasia Research Paper

...Ectodermal dysplasia is not categorized as a single disorder, but a group of disorders that are all closely related. Ectodermal dysplasias are genetic disorders that affect the tissues derived from the embryonic ectoderm. These include the skin and its appendage (hair follicles, eccrine glands, sebaceous glands, nails) and teeth. Depending on the disorder, ectodermal dysplasias can also affect the ears, nerves, fingers and toes. Dr. P. Thurman was the first doctor to describe a patient suffering from ectodermal dysplasia in 1848, but the term was not coined until 1929 by a doctor named Weech. Now, in 2015, there are over 192 disorders that have been identified, with symptoms that can range from mild to serve. These disorders, being genetic, can be inherited in five ways; (1) spontaneous mutations (2) autosomal dominant (3) autosomal recessive (4) X-linked dominant (5) X-linked recessive. Also, with the variety of inheritance, not all individuals affected with Ectodermal dysplasias will have physical abnormalities that fit the description of the typical disorder. The X-linked recessive form of...

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