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Gregor Johann Mendel

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Mendel

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Name: Gregor Johann Mendel geboren: 20. Juli 1822, gestorben 6. Januar 1884 Beruf: Katholischer Priester wird oft als „Vater der Genetik“ bezeichnet Kloster: Augustiner-Abtei St. Thomas in Alt Brünn 1856: Beginn systematischer Kreuzungsexperimente

Vorgehensweise:

Mendel kreuzte Pflanzen untereinander, um die Vererbung von Merkmalen zu erforschen. Er wählte zunächst Erbsenpflanzen, da sie mehrere konstante und unterschiedliche Merkmale aufweisen und der Blütenbau Fremdbestäubung verhindert, was die künstliche Befruchtung jedoch erschwert. Er befruchtete sie, indem er mit Pinzetten Pollen der einen Pflanze auf die Narbe der anderen auftrug und sie mithilfe von kleinen Papierbeuteln unter Verschluss hielt, sodass keine ungewollte Bestäubung durch z.B. Bienen oder Wind stattfinden konnte. Zusätzlich entfernte er vorzeitig die Staubgefäße.
Er kreuzte zwei Jahre lang Erbsensorten, bis sie gleiche und konstante Nachkommen hatten. Diese waren die Grundlage für seine Kreuzungsversuche.
Die Versuche waren genau geplant und wurden exakt protokolliert, sodass das Ergebnis statistisch abgesichert war. Dazu zählte er stets mehrere tausend Nachkommen aus.
Mendel ging davon aus, dass die Eigenschaften in dem Organismus gemeinsam wirken, aber getrennt vorliegen. Dies widersprach der damaligen Auffassung, dass sich die Merkmale vermischen und nachher nicht mehr von einander getrennt werden können. Er kam so zu der Annahme, dass es dominante und rezessive Merkmale, homozygot und heterozygot und diploide und haploide Organismen gibt.
Ergebnis:
Die drei Mendelschen Regeln: 1.Uniformitätsregel: Sie gilt, wenn zwei Eltern (Parentalgeneration P) miteinander verpaart werden, die sich in einem Merkmal unterscheiden, für das sie beide jeweils homozygot sind. Die Nachkommen der ersten Generation (Tochtergeneration F1) sind dann uniform. Das gilt sowohl für den Phänotyp als auch für den Genotyp, welcher bei allen Nachkommen der ersten Generation heterozygot ist. 1. Beim dominant- rezessiven Erbgang hat die F1 den selben Phänotyp wie das Elternteil mit dem dominanten Merkmal. 2. Beim intermediären Erbgang hat die F1 eine Mischform der elterlichen Merkmale. 2.Spaltungsregel:
Sie gilt, wenn zwei Individuen gekreuzt werden, die beide gleichartig heterozygot sind. Das kann z.B. die F1-Generation des vorherigen Abschnitts sein. Deswegen werden die Nachkommen einer solchen Heterozygoten-Kreuzung als Enkel- oder zweite Filialgeneration (F2) bezeichnet. Die Nachkommen aus dieser Paarung sind untereinander nicht mehr uniform, sondern spalten sich sowohl im Genotyp als auch im Phänotyp auf. 1. Beim dominat- rezessiven Erbgang: 3:1 2. Beim intermediären Erbgang: 1:2:1 3.Neukombinationsregel: Sie erklärt das Vererbungsverhalten von zwei Merkmalen bei der Kreuzung reinerbiger Individuen. Die Merkmale werden unabhängig voneinander vererbt, wobei ab der F2- Generation neue, reinerbige Kombinationen auftreten.
Verhältnis: 9:3:3:1 ← Es gibt eine neue Kombination in der F2

Quellen: http://de.wikipedia.org/wiki/Gregor_Mendel http://www.bossert-bcs.de/biologie/mendel/ http://www.zum.de/Faecher/Bio/SA/stoff10/mendel1.htm Bildquelle:
http://www.dujardin.ch/images/zucht_mendel4_large.jpg

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