...Exam #4 Review Comprehensive and/or early Weeks Know all conditions that cause splenomegaly All associated diseases with EBV Week 1 Mechanisms of Cellular Adaptation Types of necrosis and pathology where most likely found. Apply the definitions of Atrophy, hypertrophy, hyperplasia, hypoplasia, dysplasia, and metaplasia. Week 2 Pain Throughout Organ Systems General anatomy of kidneys, appendix, gallbladder, pancreas, spleen, male and female reproductive organs. Costochondritis vs Angina Pectoris vs Myocardial Infarctions. Rheumatoid arthritis Gout lab findings Week 3 Fluid Balance and Edema Electrolyte imbalances of sodium, potassium, calcium, and magnesium. Intra and Extra cellular concentrations of sodium and potassium as related to osmotic balance. Know the physical signs/symptoms of electrolyte imbalances including hyper and hypo natremia, kalemia, and calcemia. SIADH lab and imaging findings Diabetes insipidus lab and imaging findings Week 4 Topic 4 Acidosis and Alkalosis Know your acid-bases! Week 5 Topic 5 Cardiovascular Causes of Fatigue Cor-pulmonale, cardiomyopathies Week 6 Topic 6 Thyroid, Adrenal, Liver Fatigue Hashimoto’s thyroiditis vs. DeQuervain vs. nodular goiter vs. secondary hypothyroidism Cirrhosis, Addison disease lab tests and hormone responsible. Is it high or low? Week 7 Topic 7 Bleeding as Indicator of Disease Pathophysiology of Disseminated Intravascular Coagulation Pathophysiology of Hemophilia Ulcers Week 8...
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...She, a person seventy-one years old, had been able to live alone for eleven years perfectly fine. No one thought that this would happen. Dementia takes the lives of healthy, hard working, and amazing people; just like it did to Esther Welp. Those affected by this disease have these: memory loss, executive dysfunction, spatial disorientation, personality changes, trouble communicating, and appearance change(Shea). They lose the ability to do everyday normal tasks such as bathing, cooking, and using the restroom that people sometimes take for granted. Dementia can be caused from many different reasons, and it possible to treat it in multiple ways or even completely healed. Studies have been able to prove that aging, genetic diseases, infections, trauma, tumors, strokes, nutritional deficiencies, and diseases cause memory, cognitive decline, and personality changes; otherwise known as dementia(Shea). All of these can induce the damage of brain cells. This damage causes the inability for brain cells to correspond with one another. The brain has specific regions and each has its own job. When the cells in...
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...Submitted in Partial Fulfillment for Anatomy and Physiology, Ms. Walter Spring 2013 Things That Can Go Wrong With the Human Body: Hypothyroidism Introduction: Over time, a significant amount of problems with the human body have evolved. These problems have been developed due to both environmental and genetic factors. Dietary changes and urbanization have also played a crucial role in the development of problems that may occur. Our bodies contain a number of functioning systems that are all imperative to our survival. Without these systems, our bodies would not function and in turn, we would cease to exist. The endocrine system serves as one of the body’s ways of sending messages to the brain. It includes a number of vital glands that keep our body’s performance stable and functional. The thyroid gland is one of the most important components in the endocrine system. It is located in the neck, just under the voice box. Its primary function is to release the hormones thyroxin (T4) and triiodothyronine (T3) which control body metabolism, by taking iodine from our food and converting it into these hormones. When the levels of T4 and T3 become too low, the pituitary gland must produce a Thyroid Stimulating Hormone (TSH) which then activates the thyroid gland to generate more hormones. (Norman, 2012). If the thyroid gland does not work properly, these hormones cannot be produced on their own. This condition is known as Hypothyroidism. This paper examines the types and...
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...Thyroid Disease The thyroid gland is one of the largest endocrine glands. The thyroid gland is found in the neck, just below the voice box. It controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. The thyroid plays an important role in regulating the body's metabolism and calcium balance. The T4 and T3 hormones stimulate every tissue in the body to produce proteins and increase the amount of oxygen used by cells. These hormones are essential for life and have many effects on body metabolism, growth, and development. Several different types of thyroid problems may develop including an underactive thyroid (hypothyroidism), overactive thyroid (hyperthyroidism), and growths on the thyroid that may be nodules or cancer. As mentioned in an article from Cleveland clinic, to control metabolism, the thyroid produces hormones, T4 and T3, which tell the body's cells how much energy to use. A properly functioning thyroid will maintain the right amount of hormones needed to keep the body's metabolism functioning at a satisfactory rate. As the hormones are used, the thyroid creates replacements. The quantity of thyroid hormones in the bloodstream is monitored and controlled by the pituitary gland. When the pituitary gland, which is located in the center of the skull below the brain, senses either a lack of thyroid hormones or a high level of thyroid hormones, it will adjust Thyroid- stimulating hormones (TSH) and send it to...
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...Thyroid Disease The thyroid gland is one of the largest endocrine glands. The thyroid gland is found in the neck, just below the voice box. It controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. The thyroid plays an important role in regulating the body's metabolism and calcium balance. The T4 and T3 hormones stimulate every tissue in the body to produce proteins and increase the amount of oxygen used by cells. These hormones are essential for life and have many effects on body metabolism, growth, and development. Several different types of thyroid problems may develop including an underactive thyroid (hypothyroidism), overactive thyroid (hyperthyroidism), and growths on the thyroid that may be nodules or cancer. As mentioned in an article from Cleveland clinic, to control metabolism, the thyroid produces hormones, T4 and T3, which tell the body's cells how much energy to use. A properly functioning thyroid will maintain the right amount of hormones needed to keep the body's metabolism functioning at a satisfactory rate. As the hormones are used, the thyroid creates replacements. The quantity of thyroid hormones in the bloodstream is monitored and controlled by the pituitary gland. When the pituitary gland, which is located in the center of the skull below the brain, senses either a lack of thyroid hormones or a high level of thyroid hormones, it will adjust Thyroid- stimulating hormones (TSH) and send it to...
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...Thyroid Disease The thyroid gland is one of the largest endocrine glands. The thyroid gland is found in the neck, just below the voice box. It controls how quickly the body uses energy, makes proteins, and controls how sensitive the body is to other hormones. The thyroid plays an important role in regulating the body's metabolism and calcium balance. The T4 and T3 hormones stimulate every tissue in the body to produce proteins and increase the amount of oxygen used by cells. These hormones are essential for life and have many effects on body metabolism, growth, and development. Several different types of thyroid problems may develop including an underactive thyroid (hypothyroidism), overactive thyroid (hyperthyroidism), and growths on the thyroid that may be nodules or cancer. As mentioned in an article from Cleveland clinic, to control metabolism, the thyroid produces hormones, T4 and T3, which tell the body's cells how much energy to use. A properly functioning thyroid will maintain the right amount of hormones needed to keep the body's metabolism functioning at a satisfactory rate. As the hormones are used, the thyroid creates replacements. The quantity of thyroid hormones in the bloodstream is monitored and controlled by the pituitary gland. When the pituitary gland, which is located in the center of the skull below the brain, senses either a lack of thyroid hormones or a high level of thyroid hormones, it will adjust Thyroid- stimulating hormones (TSH) and send it to...
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...should be addressed to J. Lindholm, j.lindholm@ofir.dk Received 15 January 2011; Accepted 17 March 2011 Academic Editor: Marian Ludgate Copyright © 2011 J. Lindholm and P. Laurberg. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of iodine became acknowledged. Graves-Basedow’s disease was described. Surgical treatment evolved with extraordinary speed. Theodor Kocher observed that the clinical picture in patients after total thyroidectomy was similar to the one seen in cretinism. In 1850, the first case of hypothyroidism or myxedema was described. Less than 50 years later, effective treatment was introduced. Another 50 years later, autoimmune thyroiditis was ascertained as the most frequent cause of hypothyroidism (in areas with no iodine deficiency). This paper gives a short survey of the history of hypothyroidism and its treatment. 1. Introduction During the 50 years preceding World War I, medicine saw a wealth of new ideas and novel procedures, not in the least within the field of endocrinology. Among major achievements of this period were the recognition of the importance of the pituitary...
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...The thyroid then adjusts its production of hormones based on the amount of TSH it receives. When the thyroid does not make enough hormones, hypothyroidism occurs. (Blanchard and Abrams-Brill) Simply put, hypothyroidism is the result of an underactive thyroid. Because the thyroid controls metabolism, regulates body temperature, affects body weight, muscle strength, energy level, and fertility (Sagmill, 206), an underactive thyroid can have significant effects on individuals who are diagnosed with hypothyroidism. There are an estimated 27 million people living with hypothyroidism, the majority being female. Women are nine times more likely to develop this disease, most cases occurring during the childbearing years. (Blanchard and Abrams-Brill, 1491) While not as common; men and children are still susceptible to the disease. After the age of 65, the number of men and women with hypothyroidism evens out. (Blanchard and Abrams-Brill, 2669) Due to the role iodine plays in conjunction with hypothyroidism, individuals living in iodine deficient areas are 10 to 20 times more likely to develop hypothyroidism. Pregnancy can also bring out gestational hypothyroidism in expecting mothers, roughly 1 in 50. (Everydayhealth.com)...
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...sexual development, and many other body functions. They are responsible for helping your cells convert oxygen and calories into the energy, which is needed to help them work properly. These hormones are important in making sure your body will mature as it should and may affect how your organs function. The two most important thyroid hormones are thyroxine (T4) and triiodothronine (T3), which account for 99.9% and 0.1% of the thyroid hormones present in your blood supply. The hormone with the most biological activity is T3. Once it is released from the thyroid gland into the blood stream, a large amount of T4 is converted into T3, which is the active hormone that affects the metabolism of cells. (Ruchi Mathur) Thyroid disease is a medical condition impairing the function of the thyroid. It also occurs when the gland doesn’t supply the proper amount of hormones in the...
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...The dry eye is a largely symptomatic condition which occurs very commonly worldwide and has the tendency to develop under many circumstances1. It is usually termed as keratoconjunctivitis sicca (KCS) or simply keratitis sicca, and is caused by numerous diseases. Inflammation of the conjunctiva and accessory glands can be seen in up to 80% of patients with KCS. The terms sicca syndrome and sicca complex are also used frequently to describe dry eye associated with Sjogrens syndrome1. To avoid any confusion of these terms, the term KCS is used to refer to dry eye generally and to indicate that there is a dry eye condition present. Regardless of the underlying disease causing the dry eye, an alteration in the tear film is distinct and consistent in each case and it is this change in the tear film that causes the resultant damage to the cornea and conjunctiva1. Sjogrens syndrome is divided into two categories: Primary Sjogrens syndrome and secondary Sjogrens syndrome. The former involves only dry eyes (xerophthalmia) and dry mouth...
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...Lupus, Latin for wolf, is the word used historically to describe any chronic, usually ulcerating, skin disease. Dr. Max Gerson's rise to medical prominence in pre-WWII Germany was owed to the curative effect in lupus vulgaris of a salt-free diet bearing his name. Lupus vulgaris, a European plague of the early part of this century, was tuberculosis of the skin, a bacterial disease that has been largely eliminated through improved public health measures and, to a lesser extent, by antibacterial drugs. Today's lupus is systemic lupus erythematosus (SLE), an inflammatory disorder of connective tissue which frequently targets skin (hence the designation lupus) as well as joints, kidneys, mucous membranes, the nervous system, and virtually any other organ or system in the body. Onset of the disease may be sudden and acute, with fever, painful and swollen joints, skin rash, and influenza-like symptoms; or it may smolder for years with low level malaise and intermittent fevers. Symptoms The list of symptoms attributable to SLE is extensive and astonishing. Among symptoms most frequently observed are painful joints, usually of the hands and feet, which may also include the larger joints. Of all SLE patients, 92% endure significant joint pain. Similarly, 84% of all SLE patients suffer from fevers. Skin eruptions, including round or discoid lesions, as well as a butterfly rash presenting on the cheeks below the eyes and bridging the nose, will afflict 72%. Inflammatory kidney dysfunctions...
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...NUR160 Ca Name: Jodi Wiak | Section: 160 | Instructor: Ms. Higgins | Dates of care: 4/1/14 | Week: 1st clinical | Name: Jodi Wiak | Section: 160 | Instructor: Ms. Higgins | Dates of care: 4/1/14 | Week: 1st clinical | General Survey | Age: 85 | Sex: F | Ethnicity: Caucasion | # of days since admission: 7d | Allergies: Latex PCN | Code Status: FULL CODE | Diet: TPN | Rationale: Small bowel obstruction and resection benefit TPN over tube feedings is that all the nutrition is delivered at a cellular level making it immediately available for the body to utilize rather than making the body breakdown and absorb nutrients in the GI tract. It makes it easier on the digestive tract by giving the GI a chance to rest and heal without causing more harm. The patient also has to expend energy to breakdown foods/nutrition through the GI tract. Getting it TPN conserves the much needed energy the patient needs to heal their tissues and gain strength. | Activity: bedridden w/slight mobility with a walker | Rationale: Post surgical abdominal surgery, pt age, weakness, and recent foot surgery limiting her mobility. | Behavior/Affect: My pt was anxious when I first arrived due to her elevated B/P, N&V, and pain intolerance. By the end of shift my patient was very calm and communicative. | Isolation: | Yes | No | Culture: ⦵ | Source: ⦵ | Type of Isolation: ⦰ ⦵ | Height: 5’ 7.5” | Weight: 133 | BMI: 20.5 (BSA 1.71) | General Survey | Age: 85 | Sex:...
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...PATHO Exam 3 Study Guide * Define KEY WORDS (terminology) listed in the syllabus * Answer the OUTCOMES in the syllabus as if they are questions * Review all Activities, Games, extra videos, journal articles, etc. posted in course contents * Review the handouts from class: case studies, matching, charts, etc. Normal Values | Intracranial pressure | 5-10 mm Hg | Blood glucose | 70-130 | Hgb A1c | <5.7% | Thyroid levels | | Parathyroid levels | | Types of bone cells | Osteoblasts | Bone forming cellsThey are responsible for bone growth and repair | Osteocytes | Osteoblasts that have become trapped, imprisoned within mineralized bone matrix (MATURE BONE CELLS) | Osteoclasts | Reabsorb or remove bone during growth and repair (also assist in the release of calcium and phosphate)**bone reabsorption; bone destroying cells | *So, if one is immobilized then the osteoclastic activity is greater than the osteoblastic activity in bone marrow decreases. This is why we have debone mineralization during immobilization. Maintenance of bone integrity | This occurs through remodeling and it is a 3 phase process where existing bone is resorbed and new bone is laid down [repairs bone, does not heal bones] | Phase 1 | Activation phaseThis is where a stimulus occurs, such as a weight baring exercise, causing the formation of osteoclasts | Phase 2 | Resorption This is where osteoclasts form a cutting zone and resorb or remove bone | Phase 3 | Formation...
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...family of large organic compounds involved in many important biological processes. Following their enzymatic hydrolysis during food processing or digestion, proteins may release fragments from their primary amino acid sequence. These fragments are called peptides, and many of them are known to be physiologically active. The possible beneficial effects of bioactive peptides have attracted increasing interest in recent years. On the other hand, there are also reports suggesting that some food-derived peptides might adversely affect human health. Among these, β-casomorphin-7 (BCM7), a peptide sequence present in the milk protein β-casein, has been suggested to contribute to an increased risk for certain non-communicable diseases, such as autism, cardiovascular diseases and type I diabetes. Some literature reports have proposed possible mechanistic explanations for such associations Recognising the alleged negative effect of BCM7 on human health, EFSA deemed it necessary to perform a comprehensive review of the published scientific literature in...
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...that is not an inherent natural constituent of the food itself, in an amount that poses a reasonable possibility of injury to health, or (2) a substance that is an inherent natural constituent of the food itself; is not the result of environmental, agricultural, industrial, or other contamination; and is present in an amount that ordinarily renders the food injurious to health. The first includes, for example, a toxin produced by a fungus that has contaminated a food, or a pathogenic bacterium or virus, if the amount present in the food may be injurious to health. An example of the second is the tetrodotoxin that occurs naturally in some organs of some types of pufferfish and that ordinarily will make the fish injurious to health. In either case, foods adulterated with these agents are prohibited from being introduced, or offered for introduction, into interstate commerce. Our scientific understanding of pathogenic microorganisms and their toxins is continually advancing....
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