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Myocardial Infarction: Heart Attack

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In a myocardial infarction (MI), also commonly referred to as “heart attack,” part of the coronary circulation becomes blocked (one of the arteries that supply the heart muscle becomes blocked), so that the death of cardiac muscle cells due to lack of oxygen. Infarction means the death of an affected tissue, which is a nonfunctional area, cause of interrupted blood supply. It most commonly results from severe coronary artery disease. The consequences depend on the blockage, which may be caused by vasospasm, which is spasm of the artery stimulated by mediators released from platelets, or by atherosclerosis with acute clot formation. The blockage results a permanent loss of contraction of that portion of the heart muscle. Because the heart tissue distal to the obstruction dies and is replaced by non-contractile scar tissue, the heart muscle loses some of its strength and finally its contractile function stops. Thus, an acute myocardial …show more content…
Myocardial infarction is diagnosed when blood levels of sensitive and specific biomarkers such as cardiac troponin or CKMB are increased in the clinical setting of acute myocardial ischaemia.” (Thygesen, Alpert, White, 2007, p. 2177)
“About 25% of MI patients die before obtaining medical assistance, and 65% of MI deaths among those under age 50 occur within an hour after the initial infarction” (Martini, Nath, Bartholomew, 2012, p.699). Risk factors for Myocardial infarction can be divided into non-modifiable or modifiable risk factors. Non-modifiable risk factors are age, gender, and family history. Modifiable risk factors are stop smoking, high blood pressure treatment, and dietary modification to lower cholesterol and promote weight loss, stress reduction, diabetes control, obesity and increased physical

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