...[pic] HISTORY OF MICROSCOPE Oddly enough, the compound microscope was invented before the single lens microscope. But the instruments were not very good to start with and much more could be seen with very small lenses of short focal length. In about 1597 two Dutch eyeglass makers, Zaccharias Janssen and his son Hans were experimenting with lenses in a tube. They observed that nearby objects viewed through two lenses in line were magnified. Their device was the first compound microscope. However, their lenses were rather large and the magnification obtained was only about 10X. Galileo also designed a compound microscope, but it was only useful for reflected light. Robert Hooke built the first useable British compound microscope in about 1655. The single lens microscopes made by a Dutch amateur lens grinder Antonie van Leeuwenhoek were far superior to the early compound instruments. Van Leeuwenhoek, in about 1670, developed a method for grinding very small glass lenses. They were tiny, of the order of a millimeter in diameter, and could magnify several hundred times. Mounted in a brass plate these lenses could use transmitted light to image objects in a drop of water on the end of a metal pin. Screws were used to move the pin and focus the specimen. Van Leeuwenhoek was probably influenced by Robert Hooke’s Micrographia (1665) which he might have seen when he visited London in about 1668. Amongst his vast number of discoveries were bacteria, sperm, blood cells and a...
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...profile Followers Physics term paper on TRANSMISSION ELECTRON MICROSCOPE Friday, January 21, 2011 by STUDY PORTAL in Labels: TERM PAPERS Acknowledgement It is a pleasure of mine to find myself penning down these lines to express my sincere thanks to my teacher to give me this opportunity of preparing this Term Paper, to enhance my professional practice. I express my deep sense of gratitude to my physics teacher to give me knowledge about the topic and concept related to this particular Term Paper. Without his guidance I cannot imagine to complete my Term Paper on time. In the last, I want to thank my parents, without whom nothing was possible. Contents 1. What is TEM. 2. Principle of TEM. 3. Working of TEM. 4. Uses of TEM 5. Limitations of TEM. 6. References The Transmission Electron Microscope: The transmission electron microscope (TEM) is a scientific instrument that uses electrons instead of light to scrutinize objects at very fine resolutions. They were developed in the 1930s when scientists realized that electrons can be used instead of light to "magnify" objects or specimens under study. View inside cell via sections magnification 120,000 * 50,000X Principle: The transmission electron microscope (TEM) operates on the same basic principles as the light microscope but uses electrons instead of light. What you can see with a light microscope is limited by the wavelength of light. TEMs use electrons as “light...
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...SUBMITTED TO ENGR. PROF. O. O. ONYEMAOBI [EXAMINER] DEPARTMENT OF MATERIALS AND METALLURGICAL ENGNEERING FEDERAL UNIVERSITY OF TECHNOLOGY, OWERRI AUGUST 2005 i Markudo [2005] PREFACE The electron microscope is an indispensable modern analytical and research tool. Microscopy is employed in all branches of science to identify materials, characterize unknown substances or study the properties of known materials. This term paper surveys the applications of electron microscopy in the field of materials and metallurgical engineering. I hereby acknowledge my lecturer on Electron Optics and Microscopy (MME 604), Engr. Prof. O. O. Onyemaobi. He has been sharpening my research and writing skills since my undergraduate days. This is the third term paper I will be submitting to him. ii TABLE OF CONTENTS Title Page Preface Table of Contents CHAPTER ONE 1.0 1.1 1.2 1.2.1 1.2.2 1.2.3 Introduction Materials and Metallurgical Engineering Microscopes and Microscopy Levels of Structure Methods of Structural and Compositional Elucidation Microscopy i ii iii-v 1-12 1 1 3 4 6 8 13-24 13 13 14 16 17 18 19 21 CHAPTER TWO 2.0 2.1 2.2 2.3 2.3.1 2.3.2 2.3.3 2.3.4 Transmission Electron Microscopy Interaction of Electrons with Solids Transmission Electron Microscope (TEM) TEM Modes and Applications General Surface Information & External Morphology Contrast from an Imperfect Crystal Precipitates and Second Phases iii Markudo [2005] 2.3.5 Specialized Techniques of TEM ...
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...A microscope (from the Ancient Greek "small" "to look" or "see") is an instrument used to see objects that are too small for the naked eye. The science of investigating small objects using such an instrument is calledmicroscopy. Microscopic means invisible to the eye unless aided by a microscope. There are many types of microscopes. The most common (and the first to be invented) is the optical microscope, which uses light to image the sample. Other major types of microscopes are theelectron microscope (both the transmission electron microscopeand the scanning electron microscope), the ultramicroscope, and the various types of scanning probe microscope. The first microscope to be developed was the optical microscope, although the original inventor is not easy to identify. Evidence points to the first compound microscope appearing in the Netherlands in the late 1500s, probably an invention of eyeglassmakers there:[1] Hans Lippershey (who developed an early telescope) and Zacharias Janssen (also claimed as the inventor of the telescope). There are other claims that the microscope and the telescope were invented by Roger Bacon in the 1200s,[2] but this is not substantiated. Giovanni Faber coined the name microscope forGalileo Galilei's compound microscope in 1625 [3] (Galileo had called it the "occhiolino" or "little eye"). 2nd Century BC - Claudius Ptolemy described a stick appearing to bend in a pool of water, and accurately recorded the angles to within half a degree. ...
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...THE MICROSCOPE Much of the laboratory work in General Botany I involves the study of minute structures which are invisible of poorly seen with the naked eye. This requires the use of the microscope, the primary purpose of which is to magnify or greatly enlarge the image of the objects or organisms so their detailed structures may be studied. For our purposes, the monocular compound microscope will be used. It is an optical instrument with two lens systems: the objectives and the eyepiece or ocular. It can magnify an image up to several hundred times the actual size of an object. For effective use and proper care of the microscope, one must become familiar with its construction, parts and uses. There are three sets of parts: namely, the mechanical, illuminating, and magnifying parts. A. Mechanical Parts 1. Base- the U-shaped structure on which the microscope firmly rests in the place. 2. Pillar- the post of vertical extension of the base and to which the arm is attached. 3. Arm- the curve structure that connects the base and the body tube which serves as the handle of the microscope and at the same time supports the optical instrument. 4. Inclination joint- a movable hinge that attaches the frame of the microscope to the base and is used for tilting the microscope whenever necessary. 5. Stage- the platform upon which the slide containing the specimen to be studied is placed and is provided with a central opening allowing light to pass from below...
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...10 Technology used by Medical Technologist 1. Description: A centrifuge is a piece of equipment that puts an object in rotation around a fixed axis (spins it in a circle), applying a potentially strong force perpendicular to the axis of spin (outward). The centrifuge works using the sedimentation principle, where the centripetal acceleration causes denser substances and particles to move outward in the radial direction. At the same time, objects that are less dense are displaced and move to the center. In a laboratory centrifuge that uses sample tubes, the radial acceleration causes denser particles to settle to the bottom of the tube, while low-density substances rise to the top.[1] There are 3 types of centrifuge designed for different applications. Industrial scale centrifuges are commonly used in manufacturing and waste processing to sediment suspended solids, or to separate immiscible liquids. An example is the cream separator found in dairies. Very high speed centrifuges and ultracentrifuges able to provide very high accelerations can separate fine particles down to the nano-scale, and molecules of different masses. Large centrifuges are used to simulate high gravity or acceleration environments (for example, high-G training for test pilots). Medium-sized centrifuges are used in washing machines and at some swimming pools to wring water out of fabrics. Gas centrifuges are used for isotope separation, such as to enrich nuclear fuelfor fissile isotopes. From: https://en...
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...NIKON CORPORATION NIKON REPORT 2014 Shin-Yurakucho Bldg., 12-1, Yurakucho 1-chome, Chiyoda-ku, Tokyo 100-8331 Japan (Scheduled to relocate to the following address on Nov. 25, 2014: Shinagawa Intercity Tower C, 2-15-3, Konan, Minato-ku, Tokyo 108-6290 Japan) www.nikon.com This eco-friendly booklet was produced using FSC®-certified paper; non-VOC (volatile organic compound), vegetable-oil ink; and waterless printing technology. Printed in Japan NIKON REPORT 2014 Year Ended March 31, 2014 NIKON REPORT 2014 NIKON REPORT 2014 Independent Practitioner’s Assurance of Social and Environmental Performance Independent Practitioner’s Assurance of Social and Environmental Performance About NIKON REPORT 2014 Starting with reports published in the fiscal year ending March 2015, Nikon Corporation publishes its previously named ANNUAL REPORT as the NIKON REPORT. In addition to details regarding business performance and strategy, operational overviews, and other financial data previously published in the ANNUAL REPORT, this report comprises a broader range of non-financial data, including information on CSR activities and corporate governance. As a corporate group that continues to pursue steady growth and create new value prefaced on harmony with society, we hope that NIKON REPORT will promote further understanding of the Nikon Group among our shareholders, investors, and all other stakeholders. CONTENTS INTRODUCTION 02 Nikon’s Growth...
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...ELECTRONICS, VOL. 5, NO. 4, JULY/AUGUST 1999 1205 Optical Coherence Tomography (OCT): A Review Joseph M. Schmitt (Invited Paper) Abstract— This paper reviews the state of the art of optical coherence tomography (OCT), an interferometric imaging technique that provides cross-sectional views of the subsurface microstructure of biological tissue. Following a discussion of the basic theory of OCT, an overview of the issues involved in the design of the main components of OCT systems is presented. The review concludes by introducing new imaging modes being developed to extract additional diagnostic information. Index Terms— Imaging, interferometry, optical coherence tomography, speckle. I. INTRODUCTION HE APPLICATION of optical technology in medicine and biology has a long and distinguished history. Since the 18th century, the microscope has been an indispensable tool of biologists. With the invention of the laser in the early 1960’s, physicians gained a new surgical instrument. The development of fiber optics led to the manufacture of endoscopes that permit direct viewing of internal organs deep in the body. In the modern clinical laboratory, new optical technologies facilitate the chemical analysis of tissue samples and the counting and sizing of blood cells. In spite of these and other advances, few of the optical instruments used in medicine today take advantage of the coherent properties of light. Even most instruments that employ lasers, the ultimate generators of coherent...
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...started. (unfamiliar reader – used to clarify terms / familiar reader – expected you to demonstrate your understanding of complex concepts) Sentence Definition; To what class does (Definition) belong? How is it different / would you define? (Compare / Cause) A term is (a) class wh-word/that specific detail. Indefinite article / before both the term and class Ex) Annealing is a metalworking process / A star is a celestial body A disinfectant is an/the agent capable of destroying disease causing microorganisms. An; it does not refer to a particular representative. The; indentifies or describes the term, some previous mention of other agents. The distinguishing information in the restrictive relative clause - one involves a simple deletion / the other involves a change in word form or an entire word. 1) Enamel, in dentistry, is a hard, white inorganic material (that is) on the crown of a tooth. : the verb to be 2) A collagen is a white, inelastic protein (that is) formed and maintained by fibroblasts. : a passive verb + inf. 3) A robot is a multi-programmable device (which is) capable of performing the work of a human. : an adjective 1) A parliament is a national governing body (which has – with) the highest level of legislative power within a state: the relative pronoun and have > with 2) Pollution is a form of contamination (that often...
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...INSPECTION & TESTING OF MATERIALS COMPILED BY: SYED HAIDER ALI (COURSE MATERIAL FOR DEPARTMENTAL PROMOTION EXAMINATION (DPE)) Chapter # 1: METALLOGRAPHIC EXAMINATION: 2 Chapter # 1: METALLOGRAPHIC EXAMINATION: ................................................................... 6 1.1 INTRODUCTION: ......................................................................... 6 1.2 METALLURGICAL MICROSCOPE: .................................................... 6 1.3 SPECIMEN PREPARATION: ............................................................ 8 1.5 MICRO AND MACRO EXAMINATION:............................................. 13 1.6 STUDY OF MICROSTRUCTURES: .................................................. 14 Chapter # 2: Tensile Testing .............................................................................................................. 19 2.1 INTRODUCTION: ....................................................................... 19 2.2 PROCEDURE OF TENSILE TESTING: ............................................. 19 2.3 TENSILE PROPERTIES: ............................................................... 21 2.4 EXPERIMENTAL RESULTS OF TENSILE TESTING: ........................... 26 Chapter # 3: Bend Test ....................................................................................................................... 28 3.1 INTRODUCTION: ....................................................................... 28 3.2 TYPES OF BEND TEST: .........................
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...NIKON VS CANON | STRATEGIC MANAGEMENT ANALYSIS | | 4/1/2012 4/1/2012 Table of Contents Strategic Management Comparison between Nikon and Canon 3 Introduction 3 Nikon Company Background 4 Logo 4 History 5 Products 5 Canon Company Background 6 History 6 Logo 7 Products 7 Nikon Corporate Information 8 Mission 8 Vision 8 Canon corporate information 9 Mission 9 Vision 9 Corporate Philosophy 9 SWOT Analysis 10 Nikon 10 Strengths 10 Weaknesses 11 Opportunities 11 Threats 11 canon 12 strengths 12 Weaknesses 12 Opportunities 13 Threats 13 TOWS Matrix 14 Canon 14 Strengths – Opportunities 14 Strengths - Threats 14 Weaknesses – Opportunities 15 Weakness - Threats 15 Nikon 16 Strengths – Opportunities 16 Strengths – Threats 16 Weakness – Opportunities 16 Weaknesses – Threats 16 Corporate Governance 17 Japanese Corporate Governance 17 Nikon Corporate Governance 19 Management System 19 The Board of Directors and Executive Committee 20 Corporate Auditors and the Board of Corporate Auditors 20 Nikon Board of Directors and Corporate Auditors 21 Canon corporate governance 22 Board Of Directors 25 Porter Five Forces 26 Rivalry 26 Threat of Substitutes 27 Buyer Power 28 Supplier Power 28 Threat of new entrants 28 corporate culture 30 Nikon 30 Canon 30 Conclusion 31 References 32 Strategic Management Comparison between Nikon and Canon Introduction “One image has...
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...UTAR FHSC1214 Fundamentals of Cell Biology Trimester 1 How YOU can do well in BIOLOGY Follow the 4A’s and you can expect A’s. A ttitude • Attend ALL lectures, tutorials and practicals on time without fail. • Be attentive in class and revise your notes after class while the topic is still fresh in your mind. Why waste time re-reading 2-3 months later? • Do your assignments faithfully as they carry marks for the finals. • Come prepared for lessons (i.e. read up beforehand). • Read up beforehand before attending lectures so that you won’t be lost and wasted hours of your life week after week. • Why stress yourself out if you can avoid it? Do NOT count on last minute revision for tests and examinations, as it will be too late to catch up and seek help in areas where you may find confusing or unclear of. • Why panic before exams because you can’t find this or that? Keep separate files for lecture, tutorial and practical. File up the respective notes systematically so that you do not lose them along the semester. • Do you expect the lecturer/ tutor to be available all the time to answer your questions? It is YOUR responsibility to take the initiative to clear your doubts or satisfy your curiosity to understand certain scientific phenomena by reading up on the relevant topics. A Based on a true story… A professor at the National University of Singapore recounts how on one occasion a student consulted him days before the exam. Student:...
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...CORE SYLLABUS for National Eligibility-Cum-Entrance Test (NEET) for Admission to MBBS/BDS Courses The Medical Council of India (MCI) recommended the following syllabus for National Eligibility-cum-Entrance Test for admission to MBBS/BDS courses across the country (NEET-UG) after review of various State syllabi as well as those prepared by CBSE, NCERT and COBSE. This is to establish a uniformity across the country keeping in view the relevance of different areas in Medical Education. PHYSICS S.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. CLASS XI Physical world and measurement Kinematics Laws of Motion Work, Energy and Power Motion of System of Particles and Rigid Body Gravitation Properties of Bulk Matter Thermodynamics Behaviour of Perfect Gas and Kinetic Theory Oscillations and Waves CLASS XII Electrostatics Current Electricity Magnetic Effects of Current and Magnetism Electromagnetic Induction and Alternating Currents Electromagnetic Waves Optics Dual Nature of Matter and Radiation Atoms and Nuclei Electronic Devices CHEMISTRY S.No. 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. CLASS XI Some Basic Concepts of Chemistry Structure of Atom Classification of Elements and Periodicity in Properties Chemical Bonding and Molecular Structure States of Matter: Gases and Liquids Thermodynamics Equilibrium Redox Reactions Hydrogen s-Block Element (Alkali and Alkaline earth metals) Some p-Block Elements Organic Chemistry- Some Basic Principles and Techniques Hydrocarbons...
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...FORMULATION AND EVALUATION OF TOPICAL GEL CONTAINING AZITHROMYCIN AND PREDNISOLONE VESICLES FOR TREATING PSORIASIS Sonia Tomar, Tinku Singhal, ABSTRACT Psoriasis is a chronic, autoimmune systemic inflammatory disease, associated with metabolic syndrome, cerebrovascular disease, diabetes and many other diseases. There is various type of psoriasis but most common type of psoriasis is caused by Psoriasis vulgaris. It is characterized by rigid of skin due to increase in the level of cholesterol and fall in the level of ceramide. Apart from that it is associated with an immune system of the body means movement of immune cells from dermis to the epidermis, where they stimulate skin cells (keratinocytes) to proliferate. Various type of drug delivery system are used for the treatment of psoriasis including topical, oral or systemic but gels prepration of azithromycin and prednisolone are more effective in reduction of purities, scaling and hyperkeratosis of psoriasis plaque. Niosomal/Vesicular gel, has been explored extensively for topical application to enhance skin penetration as well as skin retention. Prednisolone and azithroycin together provide effective results in the treatment of psoriasis. Due to high entrapment efficiency and stability, gel prepration (Azithromycin & Prednisolone) reduce the scaly patches and suppression of humoral immunity. Keywords: Niosome, Immunity, Topical, Psoriasis, Gel, Azithromycin, Prednisolone. INTRODUCTION Psoriasis is recognized...
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...New Medical Devices in the US August 13 2010 Table of Contents 1. Introduction……………………………………………………………………………………………………………………………………2 2. Background and Framework……………………………………………………………………………………………………………4 2.1 Priority Medical Devices for the Netherlands…..……………………………………………………………………4 2.2 The US Vision: From see and treat to predict and prevent……………………………………………………6 2.3 Conclusions…………………………………………………………………………………………………………………………..7 3. Medical device sector in the US………………………………………………………………………………………………………8 3.1 Economic Impact…..………………………………………………………………………………………………………………8 3.2 The Sector by State…..…………………………………………………………………………………………………………10 3.3 Key Institutes: Patent Applications in the Cluster Areas…..………………………………………………….13 3.4 Conclusions…..…………………………………………………………………………………………………………………….20 4. Turning research into novel medical devices………………………………………………………………………………….22 4.1 The Medical Device Development Process…..……………………………………………………………………..22 4.2 CIMIT: A Structure for Medical Device Innovation…..………………………………………………………….23 4.3 Stanford Biodesign: Innovation as a Discipline…..………………………………………………………………..26 4.4 Conclusions and Recommendations…..……………………………………………………………………………….28 5. Summary and Conclusions…………………………………………………………………………………………………………….30 6. Acknowledgements……………………………………………………………………………………………………………………….32 7. References…………………………………………………………………………………………………………………………………….33 Appendices A1 Selection of Key Institutes A2 Results Patent Analysis A3 Research...
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