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Outline and Evaluate Research Into the Effects on Stress in the Immune System

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Outline and Evaluate research into the effects on Stress in the Immune System
(12 marks)

Stress is an environmental event or situation (a stressor), which can induce a stress response in us. When someone is experiencing a stressful situation, all the body's resources are diverted and this suppresses the immune system because of the high levels of stress hormones, corticosteroids, which shrink the thymus glands preventing the growth of T-cells. This makes us more vulnerable to infection and disease. Various studies have been devised to test whether stress makes us more vulnerable to infection and illness. 

 Research has supported the theory that stress can reduce the effectiveness of the immune system.

Kiecolt-Glaser et al 1984 devised the study of exam stress and the immune function in people exposed to high levels of stress. Blood samples were taken from medical students 1 month before their final exams (control reading) and on the first day of their exams. (stress reading) Participants also completed psychological questionnaires, and the difference in blood counts was greatest for those who reported highest levels of anxiety and social isolation. This sample of participants is an unrepresentative sample of the general population and its generalisation is therefore restricted only to medical students. Also the questionnaire is subjective and social desirability may take over the participant’s answers as they may be worrying who will see them. The perceptions of what the questions are asking will also be different for everyone i.e. individual differences which cannot be helped. On the other hand this is a quick and effective way to gather the data. There may be some observer bias as Glaser’s expectations may affect the focus and as a result reliability can be questioned. The blood samples were to measure the killer cell

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