...neurons. Neurons are responsible for sending information to a different division of the body such as the eyes, muscles, brain, ears, spinal cord, and all other neurons. Neurons are also responsible for the basic things we do, our movement, thinking process, recollections and emotions (Garrett, 2011).Without neurons, it will be difficult to function daily. A case study: Joseph is a 59-year-old construction worker who recently suffered a stroke. A small blood clot became lodged in one of the vessels serving the right side of his brain and restricted blood flow to a portion of his right precentral gyrus. Many neurons in that area were damaged or destroyed and, as a result, Joseph is partially paralyzed on the left side of his body. He can move his left leg and walk, and can also move his left arm, but his left hand and the left side of his face are paralyzed. To determine the process of neural communication and how different functioning affects a particular part of the brain can help understand how the brain damage can originate from stroke and which method would best work in the recovery from brain damage. According to the case study, Joseph's left face and hand are paralyzed, but not the rest of his arm or his leg, reasons for this are when a stroke occurs on the right side of the brain several nerve cells in the brain tissue become wounded or damage, resulting to the nerve cells unable to communicate with other cells and it functions are damage, on the left side of the body, resulting...
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...Transmission of Signals among Neurons Neurotransmitters Pharmacology of Synaptic Transmission and Behavior 4.4 Biopsychology, Eighth Edition, by John P.J. Pinel. Published by Allyn & Bacon. Copyright © 2011 by Pearson Education, Inc. 76 Chapter 4 ■ Neural Conduction and Synaptic Transmission hapter 3 introduced you to the anatomy of neurons. This chapter introduces you to their function—how neurons conduct and transmit electrochemical signals through your nervous system. It begins with a description of how signals are generated in resting neurons; then, it follows the signals as they are conducted through neurons and transmitted across synapses to other neurons. It concludes with a discussion of how drugs are used to study the relation between synaptic transmission and behavior. “The Lizard,” a case study of a patient with Parkinson’s disease, Roberto Garcia d’Orta, will help you appreciate why a knowledge of neural conduction and synaptic transmission is an integral part of biopsychology. C The Lizard, a Case of Parkinson’s Disease “I have become a lizard,” he began. “A great lizard frozen in a dark, cold, strange world.” His name was Roberto Garcia d’Orta. He was a tall thin man in his sixties, but like most paClinical tients with Parkinson’s disease, he apImplications peared to be much older than his actual age. Not many years before, he had been an active, vigorous business man. Then it happened—not all at once, not suddenly, but slowly, subtly, insidiously. Now...
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...The Soccer Mom: A Case Study on the Nervous System by Jennifer Bolognese, Misti Coronel, Anita Intorre, and Phil Stephens Biology Department Villanova University Part I—At the Soccer Game Thirty-two-year-old Phyllis Jackson was sitting on the bench at the side of the soccer field, sipping a bottle of Gatorade. Her husband, Steven, sat next to her with a concerned expression. “I’m really worried about you, honey,” he said. “I’m just a little dehydrated; I’ll be fine.” “If this were the first incident, then maybe I’d agree with you. But your boss has been on your case about your lack of concentration at work, you forgot to pick up the kids from school last week, and quite frankly, you haven’t exactly been yourself with me lately. Now you’re having fainting spells during games? Something doesn’t seem right.” “I know things haven’t been going well for me lately, but I don’t know why. I try so hard at work, at home, with the kids, to be a good wife. So maybe all this stress has made me a little unfocused and disoriented. What do you want me to do about it?” Phyllis said, blinking back tears. “I think you should see a doctor,” Steven replied, putting his arm around her and drawing her close. “The kids are getting worried, too.” Phyllis sighed. “Alright, if it will make you feel better. I really just think I need some time to relax, though.” “Well… I could drop the kids off at my sister’s tonight; that would give us a little free time…” “That’s really thoughtful of you. I could definitely...
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...have an impact on one’s physical and mental well-being. It is estimated that depression affects 1 out of 10 Americans and that 80% of people exhibiting symptoms re not receiving any form of treatment (http://www.healthline.com). Other statistics revealed that individuals exhibiting symptoms of depression are more likely to have a history of being obese, having heart disease, strokes, suffer from sleep disorders, have lower education, less access to medical care, are unemployed, and recently divorced. These biopsychosocial factors that lead to the onset of depression can also be impacted by such things as age, gender, and ethnicity. While such symptoms and factors of depression can be treated in many different ways, studies have proven that between 60-80% of all cases involving depression can successfully be treated by combining psychotherapy and pharmacological constructs (http://www.healthline.com), the latter which shall be explored in greater detail. History of Medication Although plant extracts such as opium, thorn apple St. Johns wort, Henbane, Indian hemp, deadly nightshade, hypericum oil, alcohol, caffeine, cannabis and other natural remedies have been used for past 3000 years treat depression, it wasn’t until 1957 that the first tricyclic antidepressant (TCA) known as imipramine was discovered by Ronald Kuhn and later in the same year the first Monoamine oxidase inhibitors (MAOIs), iproniazide, was introduced by Loomer, Saunders, and Kline (Fitzpatrick, 2010, p. 3), which...
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...Vicodin Table of Contents Background………………………………………… Page 1 Hydrocodone……………………………………….. Page 1 and 2 Acetaminophen……………………………………... Page 2 and 3 History and Social Impact…………………………. Page 3 and 4 Drug Abuse…………………………………………. Page 5 and 6 Conclusion…………………………………………... Page 6 and 7 Appendix …………………………………………… Page 8 and 0 Defined Terms……………………………………… Page 10 Work Cited…………………………………………. Page 11 Background: Vicodin is an orally taken painkiller composed of a combination of acetaminophen and hydrocodone, classifying it as an opioid pain reliever. In this capacity, Vicodin will bind to opioid receptors and reduce the sending of pain messages to the brain 1. Opioid receptors are used to control pain, slow breathing, and have a general calming affect. In a regular Vicodin tablet, there is 5mg of hydrocodone, which reacts with the 300mg of acetaminophen 2. Individually, hydrocodone and acetaminophen are medically used drugs that are used to relieve pain, however when employed together they having a much more hard-hitting effect. The combined drug works similar to other opiates by travelling along neurological pathways and increasing dopamine levels, resulting in euphoria and pain relief 3. Currently, Vicodin is classified as a level three controlled substance due to its tendency to cause psychological dependence, potential abuse, and its acceptance for medical treatment in the United States. As of 2006, more than 6.4 million people reported that they had misused Vicodin...
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...pushed it off to musculoskeletal system. Where ever it starts, for the patient, the pain is real, it’s their perception. It’s not up to us to judge, but up to us to help ease the pain, and hopefully one day find a cure. But first we must understand how it manifests. With no concrete scientific evidence and only theories to date, we can at least see ways to help ease the pain; therapies to help make the patients more active and have a better quality of life. Fibromyalgia: The Pathophysiology Much debate of Fibromyalgia has existed since the first diagnosis. Some people are lead to believe that it replaced Chronic Pain Syndrome and/or Chronic Fatigue Syndrome. Did it, we will examine that here. Depending on who you talk to Fibromyalgia exists, Endocrinology says no and Neurology says yes. Who’s right, which is what we will find out? What we do know; “Fibromyalgia is a chronic musculoskeletal syndrome characterized by widespread joint and muscle pain, fatigue, and tender points” (McCance RN & Huether RN, 2010, p. 1606). If that is Fibromyalgia does that not describe Chronic Pain Syndrome? Well yes and no, Chronic Pain Syndrome usually stays, is always with you all the time, whereas Fibromyalgia has exacerbations that come and go. Chronic pain Syndrome can also incorporate two different syndromes such as Fibromyalgia and Chronic Fatigue Syndrome together ("Pain," n.d.). While the exacerbations of Fibromyalgia seem to come and go, long term studies indicate that signs and symptoms...
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...pushed it off to musculoskeletal system. Where ever it starts, for the patient, the pain is real, it’s their perception. It’s not up to us to judge, but up to us to help ease the pain, and hopefully one day find a cure. But first we must understand how it manifests. With no concrete scientific evidence and only theories to date, we can at least see ways to help ease the pain; therapies to help make the patients more active and have a better quality of life. Fibromyalgia: The Pathophysiology Much debate of Fibromyalgia has existed since the first diagnosis. Some people are lead to believe that it replaced Chronic Pain Syndrome and/or Chronic Fatigue Syndrome. Did it, we will examine that here. Depending on who you talk to Fibromyalgia exists, Endocrinology says no and Neurology says yes. Who’s right, which is what we will find out? What we do know; “Fibromyalgia is a chronic musculoskeletal syndrome characterized by widespread joint and muscle pain, fatigue, and tender points” (McCance RN & Huether RN, 2010, p. 1606). If that is Fibromyalgia does that not describe Chronic Pain Syndrome? Well yes and no, Chronic Pain Syndrome usually stays, is always with you all the time, whereas Fibromyalgia has exacerbations that come and go. Chronic pain Syndrome can also incorporate two different syndromes such as Fibromyalgia and Chronic Fatigue Syndrome together ("Pain," n.d.). While the exacerbations of Fibromyalgia seem to come and go, long term studies indicate that signs and symptoms...
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...Caffeine is the most-widely consumed psychoactive substance by human beings throughout the world (Reid, 2005). This report will detail its natural origins, chemical structure (as well as those of similar substances), and the methods and dosages in which it is rendered into its usable form. Additionally, this report will detail caffeine's various biological pathways within the human body, including access to the brain and various neurotransmitter pathways. Caffeine is a chemical that occurs naturally in over 100 plant species throughout the world (Steffen, 2000). Perhaps the most widely recognized of these plants is the coffee tree, whose small seed (commonly referred to as a "bean") is roasted and then crushed into a fine powder (Weinberg and Bealer, 2001). Caffeine also occurs naturally in cocoa beans, tea leaves, kola nuts, and gurana seeds, and mate. Some of these plants, such as tea, actually bear a distinct, but similar chemical to caffeine (i.e. theophylline); these chemicals will be discussed further in the chemistry section (Steffen, 2000). Caffeine is chemically known by two names. The first is 1,3,7 -trimethylxanthine; the second is 3,7,-Dihydro-1,3,7- trimethyl-1H-purine-2,6-dione. Historically, caffeine has also gone by the name of methyltheobromine, as well as thein (Weinberg and Bealer, 2001). The chemical formula of caffeine is C8 H10 N4 O2. The molecular weight for this chemical is 194.19 atomic units. Its composition...
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...Interpreted Brain Activity Dream Contents CONCEPT LEARNING CHECK 5.3 Theories of Dreams 5 Learning Objectives States of Consciousness 5.1 5.2 Define consciousness. Describe how consciousness relates to psychology. Describe the changes in brain wave activity that occur during the different stages of sleep. Understand why sleep deprivation is harmful. Understand why deep sleep is important. Understand why REM sleep is important. Describe some common sleep disorders. 5.3 5.4 5.5 5.6 Describe the two main theories of dreams. Explain the two theories of hypnosis. Discuss the effects and benefits of meditation. List and describe the four categories of psychoactive drugs. Describe the effects of psychoactive drugs on the nervous system. 5.4 Hypnosis Critical Thinking About Hypnosis Theories of Hypnosis Altered State of Consciousness Role Playing Divided Consciousness 5.6 Drug Use Mechanism of Action of Psychoactive Drugs Depressants Alcohol Narcotics/Opiates Summary of Multiple Influences on Consciousness CONCEPT LEARNING CHECK 5.6 Effects of Psychoactive Drugs CONCEPT LEARNING CHECK 5.4 Theories of Stimulants Caffeine Nicotine Cocaine Methamphetamine Hypnosis 5.5 Meditation Meditation Defined Effects and Benefits of Meditation Hallucinogens LSD Marijuana Ecstasy CONCEPT LEARNING CHECK 5.5 Effects and Benefits of Meditation...
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...my client, Rhonda is considered dually diagnosed, I will explain the health problems that can occur from using alcohol and the effects alcohol has on the brain and body, I will explain how alcohol impacts depression, and last, I will explain the specific problems that exist in treating the dually diagnosed individual. An individual who has any combination of a mental disorder (anxiety, depression, bipolar disorder) and addiction (drugs, alcohol, sex, gambling) is considered to be dual diagnosed. (Foundations Recovery Network, 1995) In one article, Paljärvi (2009) states “experimental studies have found that alcohol intoxication can produce even severe depressive symptoms during heavy drinking episodes.” Becker (2012) states in his article, “Alcohol has anxiety-reducing properties and can relieve stress, while at the same time acting as a stressor and activating the bodies stress response systems.” According to Evans and Sullivan (2001), individuals with a history of alcohol dependence, especially those early in recovery and those who are older, show significant cognitive impairments. Individuals with major depression also have significant cognitive deficits and the two together cause double the difficulties in thinking and learning. The most helpful support for a dually-diagnosed client is family and friends because they provide empathy and are non-judgmental of the client. Along with support from family and friends, it is also important to provide the proper medical and...
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...In Partial Fulfillment Of the Requirements In HS 199 1ST semester AY 2011-2012 Presented by: Norhanifah R. Mala-atao June 2011 Chapter 1 THE PROBLEM AND ITS SCOPE Background of the Study “A cup of coffee will do.” One might say this early morning before leaving for work or for school, in the afternoon when you are so busy doing all your stuff and you feel drained, or late evening when you need to be awake to study a pile of lectures, make your requirements, prepare for your report and the like. It is really a fact that nowadays people are hooked at drinking coffee for them to stay alive and more alert. For some, it has become a habit. Aside from that, it is also undeniable that coffee production is in greater amounts. Coffee shops are widely spread, and if you passed by a grocery mart or mini-store along the corner of your streets, you can buy an instant coffee product. It is readily available in market at an affordable cost. What is really in coffee that we seem to be addicted with? It is actually the caffeine. Caffeine is a drug that is naturally produced in the leaves and seeds of many plants. It's also produced artificially and added to certain foods (www.kids.org.caffeine.html). Caffeine is defined as a drug because it stimulates the central nervous system, causing increased alertness. Caffeine gives most people a temporary energy boost and elevates mood. It is certain that the above mentioned effects are known and proven for some persons. But at what...
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...binding directly with the cholinergic receptor on the other hand; indirect-acting cholinergic stimulants put forth the same effect by inhibiting the acetylcholinesterase enzyme situated on the cholinergic synapse. For the purpose of this paper, an analysis of indirect acting cholinergic stimulants will be completed, with focus on Pyridosigmine and Prostigmin and their implications to physical therapy practice. Indirect-Acting Cholinergic Stimulants Indirect-acting cholinergic stimulants are also known as Cholinesterase inhibitors or Anticholinesterase agents. Cholinesterase inhibitors increase activity at cholinergic synapses by preventing the acetylcholinesterase enzyme from breaking down acetylcholine (ACh) after its release from the presynaptic terminal. Cholinesterase inhibitors inhibit acetylcholinesterase thus allowing more acetylcholine to remain at the synapse which results in an increase in cholinergic synaptic transmission (Ciccone, 2007). For circumstances where acetylcholine supply is low, the resulting high concentration of ACH increases the communication between nerve cells and subsequently stabilizes the symptoms associated of the condition being treated (Australia, nd). Ciccone (2007) stated that Cholinesterase Inhibitors...
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...THE NERVOUS SYSTEM The nervous system allows the animal to quickly detect, communicate and co-ordinate information about its external and internal environment so it can make efficient appropriate responses for survival and/or reproduction. The two major parts of our nervous system are the central nervous system (CNS) and peripheral nervous system (PNS). The CNS is made of the brain and spinal cord. The cranial nerves, spinal nerves and ganglia make up the PNS. The cranial nerves connect to the brain. The cranial and spinal nerves contain the axons (fibres) of sensory and motor nerve cells. Nerve cells areas are also known as neurons. Neurons are the basic unit of the nervous system. They carry information or impulses as electrical signals from one place to another in the body. There are 3 types of neurons: Sensory Neurons- Sensory neurons carry electrical signals (impulses) from receptors or sense organs to the CNS. Sensory neurons are also called afferent neurons. The cell body of sensory neurons is outside the CNS in ganglia. Motor Neurons- Motor Neurons Carry Impulses From The CNS To Effector Organs Motor Neurons Are Also Called Efferent Neurons. The Cell Bodies Of Motor Neurons Are Inside The CNS. Interneurons- These are also called intermediate, relay, or associative neurons. They carry information between sensory and motor neurons. They are found in the CNS. TOP The Structure of Neurons A Neuron consists of THREE MAIN PARTS: A. CELL...
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...incurable neurodegenerative disease characterized by the triad of chorea, cognitive dysfunction and psychiatric disturbances. Since the discovery of the HD gene in 1993, the pathogenesis has been outlined, but to date a cure has not been found. Disease modifying therapies are needed desperately to improve function, alleviate suffering, and provide hope for symptomatic patients. Deep brain stimulation (DBS), a proven therapy for managing the symptoms of some neurodegenerative movement disorders, including Parkinson’s disease, has been reported as a palliative treatment in select cases of HD with debilitating chorea with variable success. New insights into the mechanism of action of DBS suggest it may have the potential to circumvent other manifestations of HD including cognitive deterioration. Furthermore, because DBS is already widely used, reversible, and has a risk profile that is relatively low, new studies can be initiated. In this article we contend that new clinical trials be considered to test the effects of DBS for HD. INTRODUCTION Few conditions in medicine present patients and their families the challenges of Huntington’s Disease (HD). Because it is a heritable disease, the majority of individuals at risk are exposed to a turbulent environment with a parent diagnosed with HD and faced with the reality of suffering a similar fate. At-risk patients have the option to learn if they have the disease and then must confront the sad truth that the disease will end in neurologic...
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...Acquisitions Editor: Crystal Taylor Product Managers: Kelley A. Squazzo & Catherine A. Noonan Designer: Doug Smock Compositor: SPi Technologies First Edition © 2011 Lippincott Williams & Wilkins, a Wolters Kluwer business. 351 West Camden Street Baltimore, MD 21201 Printed in China All rights reserved. This book is protected by copyright. No part of this book may be reproduced or transmitted in any form or by any means, including as photocopies or scanned-in or other electronic copies, or utilized by any information storage and retrieval system without written permission from the copyright owner, except for brief quotations embodied in critical articles and reviews. Materials appearing in this book prepared by individuals as part of their official duties as U.S. government employees are not covered by the abovementioned copyright. To request permission, please contact Lippincott Williams & Wilkins at Two Commerce Square, 2001 Market street, Philadelphia, PA 19103 USA, via email at permissions@lww.com, or via website at lww.com (products and services). Library of Congress Cataloging-in-Publication Data Lambert, Harold Wayne, 1972– Lippincott’s illustrated Q&A review of anatomy and embryology / H. Wayne Lambert, Lawrence E. Wineski ; with special contributions from Jeffery P. Hogg, Pat Abramson, Bruce Palmer. — 1st ed. p. ; cm. Includes index. ISBN 978-1-60547-315-4 1. Human anatomy—Examinations, questions, etc. I. Wineski, Lawrence E. II. Title. [DNLM: 1. Anatomy—Examination Questions...
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