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Sickle Cell Lab Report

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Sickle cell disease can be diagnosed in newborns and older individual. Diagnoses tests of sickle-cell disease are based on evaluate of hemoglobin and these are some of them:
Complete blood count (CBC) is a common blood test which is a snapshot of the number of cells in the bloodstream. It is used to measure several components and features of your blood. Including the concentration of red blood cells and how much hemoglobin is in them and it also provides information on the physical characteristics of the RBCs such as the size and shape of the RBCs present.
Blood film or peripheral blood smear and also called manual differential is a thin, stained layer of blood smeared on a microscope slide. An examination of the patient’s blood film can evaluate …show more content…
This test usually preformed as a part of newborn screening.
Isoelectric focusing is highly sensitive and accurate method. It has a higher resolution than electrophoresis, but it is less common due to its high cost. As well as the requirement of well-experienced laboratory staff.
DNA analysis also called high-performance liquid chromatography, performed to diagnose the inherited disorders such as sickle cells. It can detect the mutations which occur in the genes that responsible of producing hemoglobin. It can determine whether the person is carrier or affected of sickle cell. The carrier individual has one copy of defective gene that codes for Hb S and another normal copy so he/she can live normal life; while someone who has two copies of mutant Hb S is said to be affected of sickle cell disease.
Prenatal testing provides definitive diagnosis of genetic diseases which one of them is sickle cell disease. It is done by taking a sample of amniotic fluid during 14 to 16 weeks of the

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