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Standardbred Race Horse

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The study analysed is a prospective, nonrandomized clinical trial investigating the outcome of Standardbred racehorses diagnosed with midbody suspensory ligament desmitis (MSD) and treated with platelet-rich plasma (PRP) followed by a program of gradually increasing exercise. A clear hypothesis is not evident, with the objective being to determine the outcome of the treatment in case horses. The abstract does not explain that the ‘outcome’ investigated in the study is the racing performance of the horses post treatment, evaluated by comparison of number of starts, total earnings, and earnings per start against a control group of horses.

The advantage of a prospective trial is that it allows the researcher the ability to analyse currently available …show more content…
Case selection
Each horse had moderate to severe MSD (as diagnosed by ultrasonographic examination by veterinarians at the Ohio State University), treated with a single dose of PRP followed by a program of gradually increased exercise. They also required race records for 3 consecutive years after the case horses returned to racing.

As the medical status of the control group was not available, it was unknown whether any of the control group had previously had MSD. With horses discharged 3 days after the procedure, the treatment, handling and observation of horses was not standardised. The authors do not explain why the owners were advised not to administer any nonsteroidal anti-inflammatory drugs for 1 week after the procedure.

The progression of healing was assessed every 4 weeks by means of follow-up physical and ultrasonographic examination for progression of healing and severity of lameness, with the result of this influencing each component of the exercise program allocated to the horse. The exercise program is described as standardised and controlled, however, as each component was shortened or lengthened according to the recovery status of each individual, this means that it is not in fact …show more content…
The authors state that all 9 horses with MSD returned to racing following treatment with PRP and controlled exercise, however as one of the inclusion criteria stated in the method that racing results were required for 3 years following treatment, the return to athletic ability cannot be considered a valid conclusion to be drawn from this study. We are unable to identify how many horses underwent this treatment but were not successfully rehabilitated, giving a poor indication of the success of this particular form of treatment.

There are several questions raised from the results that have not been considered in the discussion, such as:
• Is there a relationship between the severity of the lesion and the time taken to return to racing? Such as in (Crowe et al., 2004) where it was found that the prognosis was significantly affected by the ultrasonographic grade at the time of diagnosis.
• Is there a relationship between time of injury and examination?
• Did the amount of PRP injected have any bearing on the outcome?
• Is there a relationship between the number of starts per year and the length of the career?
• Is there a relationship between recovery time and career length after

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