...Purposes of Gene Cloning To study genes in the laboratory, it is necessary to have many copies on hand to use as samples for different experiments. Such experiments include Southern or Northern blots, in which genes labeled with radioactive or fluorescent chemicals are used as probes for detecting specific genes that may be present in complex mixtures of DNA. Cloned genes also make it easier to study the proteins they encode. Because the genetic code of bacteria is identical to that of eukaryotes, a cloned animal or plant gene that has been introduced into a bacterium can often direct the bacterium to produce its protein product, which can then be purified and used for biochemical experimentation. Cloned genes can also be used for DNA sequencing, which is the determination of the precise order of all the base pairs in the gene. All of these applications require many copies of the DNA molecule that is being studied. Gene cloning also enables scientists to manipulate and study genes in isolation from the organism they came from. This allows researchers to conduct many experiments that would be impossible without cloned genes. For research on humans, this is clearly a major advantage, as direct experimentation on humans has many technical, financial, and ethical limitations. Importance for Medicine and Industry The ability to clone a gene is not only valuable for conducting biological research. Many important pharmaceutical drugs and industrial enzymes are produced from cloned...
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...Best Practices in Records Management & Regulatory Compliance Andy Moore . . . . . . . . . . . . . . . . . . . . . . . . . .2 Cheryl McKinnon, Hummingbird Ltd. . . . . . . . . . . .4 Records Management: Beyond the Quick Fix There’s a movie playing at my multiplex that warns against placing blind trust in technology, because it’ll getcha in the end. I haven’t seen it yet …” The RM Challenge of Electronic Communications The world of a typical knowledge worker is changing once again. Over the last two decades the technology revolution has broadened access to authoring tools, e-mail and other forms of electronic communication … TOWER Software North America . . . . . . . . . . . . . .6 Randolph Kahn, Esq. & . . . . . . . . . . . . . . . . . . . . . . . . . .8 Barclay T. Blair, Kahn Consulting E-Mail Management: Avoiding the 6 Common Mistakes Information management has become a vital focus for all organizations to address risk mitigation, compliance and overall business continuity … Records Management Redefined: From The Backroom to the Boardroom What is Records Management? Records management is the application of policies, practices, technologies and other management controls … Del Zane and Dean Berg, Stellent . . . . . . . . . . . . .10 Turning Compliance Projects into Business Processes In the not-too-distant past, compliance initiatives often were characterized by back-office operations that involved large volumes of records … Michael McLaughlin, Exact Software . . . . . ....
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...Mongolian Educational Alliance Dorjnamjin Batmonkh Assistant Researcher National Center for Non-Formal and Distance Education Mongolia Tumendelger Sengedorj (M.A) Lecturer, Sociology Mongolian State University of Education Tsentsenbileg Tseveen (Ph.D) Researcher Mongolian Academy of Sciences Institute of Philosophy Enkhbold Delger (M.A) Researcher Mongolian Academy of Sciences Institute of Philosophy, Sociology and Law 2 Mongolian Drop Out Study Table of Contents Acknowledgement Executive Summary List of Acronyms/Abbreviations List of Tables and Figures List of Appendices 1. Introduction and Framework 1.1. Project Description and Rationale 1.2. Legislation, Regulations and Structures 1.3. Administration and Management of the Education System 1.4. Organization of the Education System 1.5. Structure of the Education System in Mongolia 1.5.1. Pre-School Education 1.5.2. Primary Education 1.5.3. Secondary Education 1.6. Alternative Pathways to Education – 1.6.1 The National Program of Non-Formal Education Development 1.6.2. The National Program for Distance Education 1.7. Review of Literature 1.8. Goals and Objectives 1.8.1. Identify the Depth of the Problem 1.8.2. Raise Awareness About the Issue of School Drop outs 1.8.3. Assess the Actual Influence of Different Factors 1.8.4. Assess...
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...Edexcel AS Politics Edexcel AS Politics ExamBuster 2009 Introduction to Unit 1- People and Politics Understanding the Examination and Exam Technique Choosing your questions In this unit you are presented with four questions. They are of equal value and each question covers one of the four sections of the specification. These are: Democracy and political participation Party policies and ideas Elections Pressure groups There is no significance to the order in which questions appear. Each question is divided into three sections (a), (b) and (c). When choosing which questions to do, the following principles are recommended: It is almost certain that you will be better off choosing your strongest question to do first. You should choose questions on the basis of how well you can answer the section (c) part. The (c) part carries 25 of the 40 marks available for the whole answer. Do not choose a question simply because you can do part (a) especially well. The (a) question is only worth 5 marks. It would be illogical to choose your strongest (a) part if you cannot do well on section (c). If you cannot decide between several (c) parts, i.e. you can do more than one equally well, make your choice on the basis of part (b) which carries 10 marks. But remember, it is the (c) parts that will determine most what your overall mark will be. So, when you first look at the exam paper, look at the (c) sections first. Assessment Objectives Each question is divided into three sections,...
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...Paradoxes in the Global War on Terror John B. Alexander, Ph.D. Introduction The approach of this monograph is to examine paradoxes encountered in the Global War on Terror (GWOT). The intent is to spark debate on disputatious issues. Clearly, many of the existing situations appear intractable given the emotional investment that has been made by the public, and exacerbated by political manipulation of elected officials. Also unavoidable are the fiscal constraints that are becoming increasingly binding. Examined in Section One are problematic premises related to the four fundamental approaches to countering terrorism; increased security, eliminating the terrorists, attacking the support infrastructure, and altering conditions that breed discontent. Despite trite, albeit politically popular, commentary proposing those methods, execution of those concepts is extremely difficult, often controversial, and sometimes counterproductive. Section Two of this monograph addresses several other policy decisions that generate problems that are difficult to resolve, but directly impact the forces involved. Among those topics are; roles of contractors, individual loyalties versus national interests, alliances of convenience, foreign response to our policy on preemption of weapons of mass destruction (WMDs), the consequences of our stated objective of spreading democracy, the impact of U.S. presence in the Gulf region, and quandary associated with defining winning. Section Three...
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...source of information about management practices. One strong example would be Henry Towne as it was he whom called for engineers to look beyond the technical side of manufacturing and become involved in the economizing of efforts within the factory itself. The greatest player in the scientific management era being Frederick W. Taylor whom was a central figure in the development of management thought. Taylor gave a push and provided credibility to the idea of management. Taylor and others promoted systematic management with its popularized label of scientific management. It was characterized by advancing technology, market growth, labor unrest, and a lack of knowledge about management, industry in the United States was ripe for methods, systems, and better ways to produce and market products. To meet this need, Taylor provided a voice. Taylor's book 'Shop Management' provided the text for the teaching of industrial management to a growing body of college students who sought positions in industry. Frederick Taylor’s theory focuses on individual worker-machine relationships in manufacturing plants, while Henri Fayol focuses on the top managers and their actions. This is the basic difference that Taylor reviewed the organization from the bottom and Fayol view it from the top (George, 1968). Frederick Taylor’s scientific management theory analyzed work using scientific methods to determine the one best way to...
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...Nihilism!!! What is Nihilism? A common (but misleading) description of nihilism is the 'belief in nothing'. Instead, a far more useful one would substitute 'faith' for 'belief' where faith is defined as the "firm belief in something for which there is no proof." A universal definition of nihilism could then well be the rejection of that which requires faith for salvation or actualization and would span to include anything from theology to secular ideology. Within nihilism faith and similar values are discarded because they've no absolute, objective substance, they are invalid serving only as yet another exploitable lie never producing any strategically beneficial outcome. Faith is an imperative hazard to group and individual because it compels suspension of reason, critical analysis and common sense. Faith is "don't let those pesky facts get in the way of our political plan or our mystically ordained path to heaven"; faith is "do what I tell you because I said so". All things that can't be disproved need faith, utopia needs faith, idealism needs faith, and spiritual salvation needs faith. Fuck faith. The second element nihilism rejects is the belief in final purpose, that the universe is built upon non-random events and that everything is structured towards an eventual conclusive revelation. This is called teleology and it's the fatal flaw plaguing the whole rainbow of false solutions from Marxism to Buddhism and everything in between. Teleology compels obedience towards the...
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...interviews with senior civil servants and ministers, in the last government, to look at the experience of policy making. It also draws on our analysis of government’s own evaluations of policy, our ‘Policy Reunions’ looking at the factors behind policy success and the extensive academic literature on policy making. As such, it forms the evidential and analytic base for our recommendations report, Making Policy Better. This report is largely the work of the Institute for Government’s Senior Researcher Michael Hallsworth. In its early stages, the research was led by former Institute Fellow, Simon Parker, and in the later stages was overseen by the Institute’s Programme Director, Jill Rutter. It needs to be read alongside our working paper, System Stewardship, which looks at the future of policy making. Further information about the Institute’s work on better policy making, including case studies from the ‘Policy Reunions’ and details of follow up events can be found in the Better Policy Making section of our website at...
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...CR TOPIC-WISE EXERCISES (700-800 LEVEL) 1 The 700-800 Club Critical Reasoning Critical Reasoning Topic 1: CONCLUSION 1. • • • • • 2. In the United States, about $5,200 per person per year is spent on health care, while in Britain the amount is about half that. A recent study indicated that middle-aged white Americans have a significantly higher rate of diabetes and heart disease than do middle-aged white Britons. Even after eliminating from the study the lifestyle differences of diet, exercise, smoking, and drinking, the data showed that the Americans have poorer health than their British counterparts. The statements above, if true, best support which of the following assertions? Health care spending in the United States should be reduced by 50%. More expensive health care causes a higher incidence of certain diseases. The money spent on health care in the United States is not being used effectively. The average health care spending for middle-aged white Americans is probably less than the average health care spending for Americans in general. Something other than diet, exercise, smoking, and drinking must account for the difference in health for the two groups in the study. Spokesperson: In the 2006 election of the city mayor, 55% of the voters were female. All the voters were between ages 18 and 70 and 2/3 of them supported the incumbent mayor. The incumbent mayor won the election with a substantially greater number of votes than any other...
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...FROM GREAT TO GHASTLY: HOW TOXIC ORGANIZATIONAL CULTURES POISON COMPANIES THE RISE AND FALL OF ENRON, WORLDCOM, HEALTHSOUTH, AND TYCO INTERNATIONAL David R. Lease, Norwich University Abstract This paper presents an analytical and comparative study of four recent corporate scandals involving organizations that had previously been recognized as both ethically and organizationally sound. Based on these case studies, the following issues are discussed: (1) The role of leader behavior and organizational/leadership styles in shaping the corporate organizational culture of an organization, and (2) The extent to which this culture renders the organization and its members (including the top executives) prone to ethical misbehavior. The four companies selected for this case analysis are: Enron Corporation, WorldCom, Inc., Tyco International, Ltd., and HealthSouth Corporation. Each case is considered individually. The basic elements in the scandal are outlined and the principal aspects of each organization’s corporate culture discussed, with special emphasis on the influence of leadership styles and leadership behavior/practices on organizational culture. The four cases are then compared and contrasted in the light of the existing evidence on the relation between corporate culture and ethical misbehavior. PRELUDE “We were doing something special. Magical. It wasn’t a job – it was a mission. We were changing the world. We were doing God’s work.” – Jeffrey Skilling, former Enron COO, President...
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...Transportation specialist, Hunton & Williams (Greg, “Why we should invest today in 'Airports Inc.'”. March. http://thehill.com/blogs/congress-blog/labor/218525-faa-why-we-should-invest-today-in-airports-inc) With the latest Federal Aviation Administration (FAA) forecast predicting a doubling of passengers and cargo by 2030, the current funding system is not up to the job of ensuring airports will have the infrastructure they need to handle such dramatic increases in traffic. This will have far-reaching consequences. Commercial airports are powerful economic engines, generating 10.5 million jobs and $1.2 trillion for the U.S. economy, according to a new Airports Council International-North America study. Across the country, workers and businesses count on local airports to attract investment and move people and goods around the world. Since 2001, the total number of jobs associated with airports has increased by more than 50 percent. Despite unprecedented growth and clear evidence of the economic benefits of infrastructure investments, airports expect to have $80 billion in unmet needs through 2015 because of the flawed system used to pay for infrastructure projects. That has not always been the case. Airports generated millions of jobs and trillions of dollars for local communities between 2001 and 2010 because President Bill Clinton and Congress made two decisions to improve airport infrastructure planning and investment in 2000. The first decision allowed local communities...
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...House of Commons Health Committee Modernising Medical Careers Volume II Written evidence Ordered by The House of Commons to be printed 8 November 2007 HC 25-II, Session 2007-08 Published on 14 November 2007 by authority of the House of Commons London: The Stationery Office Limited £20.50 The Health Committee The Health Committee is appointed by the House of Commons to examine the expenditure, administration, and policy of the Department of Health and its associated bodies. Current membership Rt Hon Kevin Barron MP (Labour, Rother Valley) (Chairman) Charlotte Atkins MP (Labour, Staffordshire Moorlands) Mr Ronnie Campbell MP (Labour, Blyth Valley) Jim Dowd MP (Labour, Lewisham West) Sandra Gidley MP (Liberal Democrat, Romsey) Dr Doug Naysmith MP (Labour, Bristol North West) Mike Penning MP (Conservative, Hemel Hempstead) Mr Lee Scott MP (Conservative, Ilford North) Dr Howard Stoate MP (Labour, Dartford) Mr Robert Syms MP (Conservative, Poole) Dr Richard Taylor MP (Independent, Wyre Forest) Powers The Committee is one of the departmental select committees, the powers of which are set out in House of Commons Standing Orders, principally in SO No 152. These are available on the Internet via www.parliament.uk. Publications The Reports and evidence of the Committee are published by The Stationery Office by Order of the House. All publications of the Committee (including press notices) are on the Internet at www.parliament.uk/healthcom Committee staff The current staff...
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...C hapter Two: The Basics of Logical Reasoning The Logical Reasoning Section The focus of this book is on the Logical Reasoning section of the LSAT, and each Logical Reasoning section contains a total of 24 to 26 questions. Since you have thirty-five minutes to complete the section, you have an average of approximately one minute and twenty-five seconds to complete each question. Of course, the amount of time you spend on each question will vary with the difficulty of each question and the total number of questions per section. For virtually all students the time constraint is a major obstacle, and as we progress through this book we will discuss time management techniques as well as time-saving techniques that you can employ within the section. The Section Directions Each Logical Reasoning section is prefaced by the following directions: “The questions in this section are based on the reasoning contained in brief statements or passages. For some questions, more than one of the choices could conceivably answer the question. However, you are to choose the best answer; that is, the response that most accurately and completely answers the question. You should not make assumptions that are by commonsense standards implausible, superfluous, or incompatible with the passage. After you have chosen the best answer, blacken the corresponding space on your answer sheet.” On average, you have 1 minute and 25 seconds to complete each question. Because these directions precede...
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...Stress at Work A report prepared for The Work Foundation’s Principal Partners Ricardo Blaug Amy Kenyon Rohit Lekhi Contents Executive Summary Introduction 1. What is stress? 1.1 Defining stress 1. Explaining stress 1.3 Stress and ill-health 2. An epidemic of stress? .1 The extent of stress . The costs of stress .3 The victims of stress .4 The causes of stress 3. Why now? 3.1 Stress, work and contemporary life 3. Stress and happiness 3.3 Stress and social status 4. The sceptics 4.1 Problems of method and measurement 4. Putting stress in perspective 4.3 Therapy culture? 5. Legal and policy contexts 5.1 Stress and the law 5. Stress and public policy 6. Interventions 6.1 What does the evidence say? 6. Focussing on prevention Conclusion Bibliography 4 12 14 14 17 19 25 5 6 8 31 35 35 38 43 47 47 5 58 62 6 68 71 71 79 88 89 Stress at Work List of Tables, Figures and Boxes Table 1: Effects of stress on bodily functions Figure 1: Model of work-related stress Figure : The impact of workplace demands on physiological and psychological performance Figure 3: How stressful is your work environment? Figure 4: Overwork concern in organisations Figure 5: Self-reported Illness accentuated by work Figure 6: Estimated days lost due to self-reported work-related injury or illness Figure 7: Work-related mental ill-health Figure 8: Percentage of organisations where workers identify stress to be the leading hazard of concern by sector Figure 9: Percentage reporting...
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...CHAPTER 1 THE PROBLEM AND ITS BACKGROUND Introduction States and nations since the existence of the first known civilization have been struggling to establish stability on the administration of its affairs. One of these, which is inevitable is to suppress corruption that seems to worsen. (Olivares-Cunanan, 2013) Although there is no known document that will lead us to where corruption began and who started this practice, there are already existing documents that proposes how it started and the reason why this exists. Corruption began in the early period as far back as the old Egyptian kingdom. There is also a clear founding that corruption through its most common form existed in other civilizations that existed in the early ancient world. In the Athenian state council, bribery is common in order for the major power the so-called elite to implement what they want. The same practice was committed by roman emperors who used give lands to the senate members in order for the latter body to be on their side. (Freille, 2007). In the modern era, documents from the past that can possibly tell us where and when corrupt practices have begun may seem to be impossible to retrieve, and if ever possible, these documents may have a little relevance to no use at all in the study on how we can curtail at least corrupt practices on the national scale. ( Co, 2007) Defining what is corruption and determining its root cause is one of the center of interest of analysts and international organizations...
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