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New Test May Improve Cervical Cancer Detection

Nov. 23, 2012 — Routine smear tests have considerably reduced the number of cases of cervical cancer, but despite intensive screening 250 women in Sweden still die from the disease every year. Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have developed new methods of minimizing the number of missed cases and making diagnosis more reliable.
Since the introduction of organized screening in Sweden in the 1960s, the number of women being diagnosed with and succumbing to cervical cancer has fallen dramatically. Screening, where a sample of cells is collected from the cervix and examined under an optical microscope, detects early cell changes so that they can be treated before they cause cancer.
However, despite intensive screening 250 women still die from cervical cancer each year in Sweden, and a further 500 develop the disease.
The sensitivity of the current test is low, which means that cell samples must be taken at least ever three years. A large number of tests must also be repeated because of unreliable results -- something which causes anxiety among patients and additional costs for the health service. Researchers at Sahlgrenska Academy, University of Gothenburg have now developed a complementary test capable of minimizing the number of missed cancer cases. "Around 70 per cent of all cervical cancer cases are caused by two specific virus types, known as HPV16 and HPV18. We have developed a method that identifies proteins of these oncogenic viruses in cells, enabling a more objective interpretation of the test results," explains Maria Lidqvist, a doctoral student, who presents the method in her thesis. "This method can hopefully produce a more reliable diagnosis in uncertain cases and reduce the number of missed cancer cases, as well as the number of women who have to be re-called because of cell samples that are difficult to interpret." The research behind this method has been financed by the Swedish Research Council and conducted at Sahlgrenska Academy, University of Gothenburg, in collaboration with Fujirebio Diagnostics AB in Gothenburg

Source: http://www.sciencedaily.com
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Cervical cancer is a disease wherein cells of the body grow out of control and causes infection to the cervix. This is caused by different factors like early engaged in sexual intercourse and even vices like smoking. We all know that this is one of the diseases that cause death to most women. In this study, it implies that cervical cancer is now preventive especially if it is early detected. There are some screening and vaccines that are now discovered for us women to be protected against from cervical cancer. Study shows that cells in the body can be detected before it causes cancer. Although there are still cells that are difficult to interpret but in this way, we can now lower the number of cervical cancer patients. From this study, we learn to be hopeful and positive despite of circumstances that every person encounters. We still do the best we could just to help other people especially cancer patients regardless of its type. We all know that cancer is still no cure but we do our best to extend one’s life and live as happy as we could while we still exist and keep this people safe from complications that could gradually kill them.

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