...The Rh factor (ie, Rhesus factor) is a red blood cell surface antigen that was named after the monkeys in which it was first discovered. Rh incompatibility, also known as Rh disease, is a condition that occurs when a woman with Rh-negative blood type is exposed to Rh-positive blood cells, leading to the development of Rh antibodies. Rh incompatibility can occur by 2 main mechanisms. The most common type occurs when an Rh-negative pregnant mother is exposed to Rh-positive fetal red blood cells secondary to fetomaternal hemorrhage during the course of pregnancy from spontaneous or induced abortion, trauma,[1] invasive obstetric procedures, or normal delivery. Rh incompatibility can also occur when an Rh-negative female receives an Rh-positive blood transfusion. In part, this is the reason that blood banks prefer using blood type "O negative" or "type O, Rh negative," as the universal donor type in emergency situations when there is no time to type and crossmatch blood. The most common cause of Rh incompatibility is exposure from an Rh-negative mother by Rh-positive fetal blood during pregnancy or delivery. As a consequence, blood from the fetal circulation may leak into the maternal circulation, and, after a significant exposure, sensitization occurs leading to maternal antibody production against the foreign Rh antigen. Once produced, maternal Rh immunoglobulin G (IgG) antibodies may cross freely from the placenta to the fetal circulation, where they form antigen-antibody complexes...
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...Unit# 5 Name: Joane Elsy Date 11-05-2015 Chapter 13: Blood Human Anatomy & Physiology 11 - Review Packet Circulation and Body Defense. Chapter 13: Blood * List the major components of blood. The blood consists of red blood cells, white blood cells, platelets, and plasma (the liquid portion). Define hematocrit, and explain how it is determined. Hematocrit (HCT) is the percentage of the cells in a blood sample. This is obtained by allowing the sample to stand (clotting is prevented), allowing the cells to separate and sink to the bottom. This is further centrifuged and the percentage of the cells and liquid is determined. Describe a red blood cell. A red blood cell is a biconcave disk that has no nucleus. Describe the life cycle of a red blood cell. a. Nutrients from food are absorbed from the small intestine into the bloodstream. b. The blood transports the absorbed nutrients to the red bone marrow tissue. c. The red bone marrow produces red blood cells. d. The red blood cells circulate for about 120 days. e. Damaged and old red blood cells are destroyed in the liver. f. The resulting biliverdin is converted to bilirubin that is excreted in the bile from the liver. 2. Distinguish between oxyhemoglobin and deoxyhemoglobin. Oxyhemoglobin is hemoglobin combined with oxygen. Deoxyhemoglobin is hemoglobin that has released its oxygen. Explain what is meant by a red blood cell count...
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...“Rhesus (RH) Incompatibility Disease” Sharon C. Clatterbuck Ottawa University In partial fulfillment of the requirements for the Proseminar Class Dr. Richard Kimberly. November 9, 2004 All the technology of our medical institutions and doctors do no good unless each female who becomes pregnant takes advantage of the prenatal care that is offered to them. According to the article titled “Routine ABO and RH Typing: An Introduction”, Phillip Levine and R.E. Stetson were the first scientists to discover the rhesus blood groups in 1939. Soon after their amazing discovery, Karl Landsteiner and A.S. Weiner discovered the ABO blood typing system in the late 1940’s, which ultimately lead to discovery of the Rh differences. Several medical studies and journals have concluded that the father is the basis of all fetal blood typing. The problem arises when the father’s blood type is positive and the mother’s blood type is negative, thus causes a condition called Rhesus (RH) Incompatibility or the RH Incompatibility Disease. (Mark-Maris) Women who receive proper treatment and testing during their first prenatal visit and subsequent visits can avoid most complications in their pregnancy, including the Rhesus Incompatibility. John M Bowman of the Canadian Medical Association states “the condition was first described as a medical problem in pregnancies in 1609, during the birth of a set of twins by a French midwife. The first twin had a severe case of Rh Incompatibility...
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...Pediatrics Ductus arteriosus: shunts blood from the pulmonary artery to the aorta, bypassing the lungs Foramen ovale: shunts blood from the right atrium to the left atrium, bypassing the right ventricle and pulmonary vasculature Gravida: # of previous pregnancies Para: # of previous births Erythroblastosis Fetalis- Hemolytic disease of the newborn resulting from fetal-maternal Rh incompatibility Apgar Scoring- Assessment of newborn well-being. The higher the score, the healthier the baby. Silverman Scoring- An index of respiratory distress. The lower the Silverman score, the healthier the child Choanal Atresia- obstruction of the nasal airway; can be caused by unilateral or bilateral membraneous or bony occlusion. Diagnosis can be confirmed by the inability to pass a catheter through the nares, by cessation of air movement when the mouth is held closed, and by X-ray. Persistent Pulmonary Hypertension of the Neonate (PPHN)- ADA Persistent Fetal Circulation (PFC) - characterized by pulmonary vasoconstriction which results in high pulmonary vascular resistance; this pulmonary hypertension in turn keeps open (or reopens) the fetal cardiac shunts (the foramen ovale and/or the ductus arteriosis). The end result is right-to-left shunting and hypoxemia. Nitric Oxide therapy new treatment for PPHN. Bronchopulmonary Dysplasia (BPD)- BDP is applied to those infants who require mechanical ventilation during their first week of life, who remain dependent...
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...BIOLOGY 105 - INTRODUCTION TO BIOLOGY DOCUMENTATION OF COMPETENCY GENERAL: Enter all assigned DOC sections into a bound notebook. The DOC, which is your own personal handwritten work, is due before each examination. You need to draw in almost all areas of the DOCs. You can trace or just make a rough drawing but you are not allowed to duplicate/print pictures. You must label the parts of the pictures on your own. Submit the DOC on time to get credit. DOC #1 Objective: Describe the classification and common characteristics of living organisms. I. Describe and give an example of each level of organization from atoms to ecosystems. For tissues please list and draw a diagram of one example of the 4 major types and list function for each. For organ systems please diagram and label the digestive system and list one major function for each organ. Define and/or diagram (your choice – demonstrate your understanding): a. metabolism b. homeostasis c. interaction with the environment d. flow of energy from sun to autotrophs, heterotrophs and decomposers e. cycling of carbon using concepts of respiration and photosynthesis (use equations) f. reproduction g. DNA and genes h. evolution - mutations, diversity, adaptive trait, natural selection, extinction i. unity and diversity of life and the usefulness of the theory of evolution in explaining both the...
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...Physiology of Blood Components, Characteristics, Functions of Blood Major Components of Blood 1. Formed elements - the actual cellular components of blood (special connective tissue) a.erythrocytes - red blood cells b.leukocytes - white blood cells c.platelets - cell fragments for clotting 2. Blood plasma - complex non-cellular fluid surrounding formed elements; protein & electrolytes. Separation of Components in a Centrifuge VOLUME LAYER clear/yellowish PLASMA 55% top thin/whitish buffy coat proerythroblast ->early (basophilic) erythroblast ->late (polychromatophilic) erythroblast ->(hemoglobin) normoblast -> (nucleus ejected when enough hemoglobin)reticulocyte -> (retaining some endoplasmic reticulum) ERYTHROCYTE life span: hemocytoblast -> reticulocyte 3-5 DAYS reticulocyte -> ERYTHROCYTE 2 DAYS (in blood) ERYTHROCYTE lifespan 100-120 DAYS (primarily destroyed by macrophages in the spleen) 3. Regulation of Erythropoiesis a. hormonal controls - erythropoietin is the hormone that stimulates RBC production DECREASED oxygen level in blood causes KIDNEYS to increase release of erythropoietin 1. Less RBCs from bleeding 2. Less RBCs from excess RBC destruction 3. Low oxygen levels (high altitude, illness) ...
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...THE NEWBORN WITH SPECIAL CONSIDERATIONS A preterm infant is usually defined as a live-born infant born before the end of week 37 of gestation; another criterion is a weight of less than 2,500 grams (5lb 8oz) at birth I. INCIDENCE Occurs approximately 7% of live births of white infants, in Afro-American infants the rate is doubled 14% (Thilo & Rosenberg, 2003) CAUSES/FACTORS ASSOCIATED WITH PRETERM BIRTHS 1. Low socio-economic status 2. Poor nutritional status 3. Lack of prenatal care 4. Multiple pregnancy 5. Previous early birth 6. Race (non-whites have higher incidence than whites) 7. Cigarette smoking 8. Age of the mother (highest incidence is in mothers younger than age 20) 9. Order of birth (early termination is highest in first pregnancies and in those beyond 4th pregnancies) 10. Closed spaced pregnancies 11. Abnormalities of mother’s reproductive system, such as intrauterine septum 12. Infections (especially UTI) 13. Obstetric complications (PROM, premature separation of placenta 14. Early induction of labor 15. Elective cesarean birth ASSESSMENT A. History – detailed pregnancy history will reveal reason for the preterm birth; be careful not to convey disapproval of reported pregnancy behaviors such as smoking, etc. Being overburdened with guilt may be detrimental to her attempts to bond with her infant B. Appearance Criteria Posture Premature infant Resting posture – characterized by very little, if any, flexion in upper extremities and only partial flexion of...
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...Matching Questions Figure 17.1 Using Figure 17.1, match the following: 1) Monocyte. Answer: B Diff: 1 Page Ref: 659; Tbl. 17.2 2) Lymphocyte. Answer: D Diff: 1 Page Ref: 659; Tbl. 17.2 3) Eosinophil. Answer: C Diff: 1 Page Ref: 658; Tbl. 17.2 4) Neutrophil. Answer: A Diff: 1 Page Ref: 657; Tbl. 17.2 5) Most common white blood cell found in whole blood. Answer: A Diff: 1 Page Ref: 657; Tbl. 17.2 6) Mounts an immune response by direct cell attack or via antibodies. Answer: D Diff: 1 Page Ref: 659; Tbl. 17.2 7) Kills parasitic worms. Answer: C Diff: 1 Page Ref: 658; Tbl. 17.2 8) Becomes a macrophage. Answer: B Diff: 1 Page Ref: 659; Tbl. 17.2 9) Phagocytizes bacteria. Answer: A Diff: 1 Page Ref: 657; Tbl. 17.2 Match the following: 10) Nucleus has two lobes; contains granules of lysosomal enzymes; functions in phagocytosis of antigen‐antibody complex. Answer: B Diff: 1 Page Ref: 658 11) Nucleus is multilobed; functions as a phagocyte; contains fine indistinct granules. Answer: E Diff: 1 Page Ref: 657 A) Erythrocyte B) Eosinophil C) Basophil D) Monocyte E) Neutrophil 12) Transports CO2 and oxygen. Answer: A Diff: 1 Page Ref: 650 13) Contains a U‐ or an S‐shaped nucleus; granules stain very dark; releases histamine and heparin. Answer: C Diff: 1 Page Ref: 659 ...
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...UNDERSTANDING THE HUMAN BODY NOTES Anatomical Position - Posterior = Back Anterior = Front Dorsal = Back Ventral = Front Medial = Middle Lateral = Side Superior = Above Inferior = Below Proximal = Near point of attachment / Beginning Distal = Away from point of attachment / end Cephalic = Head Caudal = Tail Anatomical Guides – Using a known anatomical structure or region identifying an underlying or adjacent structure. Linear Guide – Drawing a real or imaginary line to locate an anatomical structure. Anatomical Limits – Proximal and distal aspects of an Anatomical structure. Planes - imaginary divisions of the human body. Sagittal – Cut the body in half from Left Right Midsagittal – Equal part left right Parasagittal – Non-equal left right parts. Coronal – Dividing body from front back Transverse – Divides the body into superior and inferior Body Cavities - The human body consists of the following body cavities: Dorsal body cavity Cranial cavity- enclosed by the Skull and contains the brain, eyes, and ears. Spinal canal - enclosed by the spine and contains the spinal cord. Ventral body cavity Thoracic cavity enclosed by the ribcage and contains the lungs and heart. Abdominopelvic cavity Abdominal cavity, enclosed by the ribcage and pelvis and contains the Kidneys, ureters, stomach, intestines, liver, gallbladder, and pancreas Pelvic cavity, enclosed by the pelvis and contains bladder, anus and reproductive system. Pelvic...
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...Addison’s Disease Addisonian Anemia Albright’s Syndrome Alport’s Syndrome Alzheimer’s Argyll-Robertson Pupil Arnold-Chiari Malformation Barrett’s Bartter’s Syndrome Becker’s Muscular Dystrophy Bell’s Palsy Berger’s Disease Bernard-Soulier Disease Berry Aneurysm Bowen’s Disease Brill-Zinsser Disease Briquet’s Syndrome Broca’s Aphasia Brown-Sequard Bruton’s Disease Budd-Chiari Buerger’s Disease Burkitt’s Lymphoma Caisson Disease Chagas’ Disease Chediak-Higashi Disease Conn’s Syndrome Cori’s Disease Creutzfeldt-Jakob Crigler-Najjar Syndrome Crohn’s Curling’s Ulcer Cushing’s Cushing’s Ulcer de Quervain’s Thyroiditis Primary adrenocortical deficiency Pernicious anemia (antibodies to intrinsic factor or parietal cells → ↓IF → ↓Vit B12 → megaloblastic anemia) Polyostotic fibrous dysplasia, precocious puberty, café au lait spots, short stature, young girls Hereditary nephritis with nerve deafness Progressive dementia • Loss of light reflex constriction (contralateral or bilateral) • “Prostitute’s Eye” – accommodates but does not react • Pathognomonic for 3°Syphilis • Lesion pretectal region of superior colliculus Cerebellar tonsil herniation through foramen magnum = see thoracolumbar meningomyelocele Columnar metaplasia of lower esophagus (↑ risk of adenocarcinoma)- constant gastroesophageal reflux Hyperreninemia Similar to Duchenne, but less severe (mutation, not a deficiency, in dystrophin protein) CNVII palsy (entire face; recall...
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...BLOOD FUNCTIONS OF THE CIRCULATORY SYSTEM The circulatory system consists of the heart, blood vessels, and blood. The term cardiovascular1 system refers only to the heart and vessels, which are the subject of chapters 19 and 20. The study of blood, specifically, is called hematology.2 The fundamental purpose of the circulatory system is to transport substances from place to place in the body. Blood is the liquid medium in which these materials travel, blood vessels ensure the proper routing of blood to its destinations, and the heart is the pump that keeps the blood flowing. More specifically, the functions of the circulatory system are as follows: Transport * The blood carries oxygen from the lungs to all of the body's tissues, while it picks up carbon dioxide from those tissues and carries it to the lungs to be removed from the body. * It picks up nutrients from the digestive tract and delivers them to all of the body's tissues. * It carries metabolic wastes to the kidneys for removal. * It carries hormones from endocrine cells to their target organs. * It transports a variety of stem cells from the bone marrow and other origins to the tissues where they lodge and mature. Protection * The blood plays several roles in inflammation, a mechanism for limiting the spread of infection. * White blood cells destroy microorganisms and cancer cells. * Antibodies and other blood proteins neutralize toxins and help to destroy pathogens. * Platelets...
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...------------------------------------------------- Top of Form My Courses --> HNC 310 --> EXAM SCHEDULE and GRADING print contact faculty contact tech | Pathology - Module 1: Introduction to the course - Unit 1: Course Requirements - Item Number: 1 Lecture | Title: | EXAM SCHEDULE and GRADING | Fall 2013 EXAM SCHEDULE Dates | | Percent of Grade | August 25, 2014 | Course begins | | September 18, 2014 | Exam 1 | 25% | October 16, 2014 | Exam 2 | 25% | November 13, 2014 | Exam 3 | 25% | December 11, 2014 | Exam 4 | 25% | A final average grade of C+ or better (a numerical grade of 74 or higher) is required to pass this course. ------------------------------------------------- Top of Form My Courses --> HNC 310 --> CELL PATHOLOGY print contact faculty contact tech | Pathology - Module 2: Module Two - Unit Number: 1 Unit Title: CELL PATHOLOGY Unit Objectives After reading this chapter, viewing the PowerPoint presentation and the accompanying lecture notes, and completing the study activities, the student will be able to: 1. Describe the normal structure and function of the cell. 2. Discuss the adaptive structural and functional changes that occur in cells as a result of changes in homeostasis. 3. Explain the adaptive structural and functional changes associated with atrophy, hypertrophy, hyperplasia...
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...LECTURE NOTES For Nursing Students Human Anatomy and Physiology Nega Assefa Alemaya University Yosief Tsige Jimma University In collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education 2003 Funded under USAID Cooperative Agreement No. 663-A-00-00-0358-00. Produced in collaboration with the Ethiopia Public Health Training Initiative, The Carter Center, the Ethiopia Ministry of Health, and the Ethiopia Ministry of Education. Important Guidelines for Printing and Photocopying Limited permission is granted free of charge to print or photocopy all pages of this publication for educational, not-for-profit use by health care workers, students or faculty. All copies must retain all author credits and copyright notices included in the original document. Under no circumstances is it permissible to sell or distribute on a commercial basis, or to claim authorship of, copies of material reproduced from this publication. ©2003 by Nega Assefa and Yosief Tsige All rights reserved. Except as expressly provided above, no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, recording, or by any information storage and retrieval system, without written permission of the author or authors. This material is intended for educational use only by practicing health care workers or students and faculty...
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...00_078973706x_fm.qxd 1/14/08 2:42 PM Page i NCLEX-PN ® SECOND EDITION Wilda Rinehart Diann Sloan Clara Hurd 00_078973706x_fm.qxd 1/14/08 2:42 PM Page ii NCLEX-PN® Exam Cram, Second Edition Copyright © 2008 by Pearson Education All rights reserved. No part of this book shall be reproduced, stored in a retrieval system, or transmitted by any means, electronic, mechanical, photocopying, recording, or otherwise, without written permission from the publisher. No patent liability is assumed with respect to the use of the information contained herein. Although every precaution has been taken in the preparation of this book, the publisher and author assume no responsibility for errors or omissions. Nor is any liability assumed for damages resulting from the use of the information contained herein. ISBN-13:978-0-7897-2706-9 ISBN-10: 0-7897-3706-x Library of Congress Cataloging-in-Publication Data Rinehart, Wilda. NCLEX-PN exam cram / Wilda Rinehart, Diann Sloan, Clara Hurd. -- 2nd ed. p. cm. ISBN 978-0-7897-3706-9 (pbk. w/cd) 1. Practical nursing--Examinations, questions, etc. 2. Nursing--Examinations, questions, etc. 3. National Council Licensure Examination for Practical/Vocational Nurses--Study guides. I. Sloan, Diann. II. Hurd, Clara. III. Title. RT62.R55 2008 610.73'076--dc22 2008000133 Printed in the United States of America First Printing: February 2008 Trademarks All terms mentioned in this book that are known to be trademarks or service marks have been appropriately...
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