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Jaundice In The Newborn

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Jaundice in the Newborn

Jaundice and how it occurs
Jaundice, or hyperbilirubinemia is a common condition found in newborn infants associated with high levels of bilirubin within the body. It is a common occurrence in infants 35-36 week gestation, with premature babies also having an increased risk for developing it. Most cases of jaundice within newborns occur as a result of increased erythrocyte breakdown and a decrease in the reuptake of bilirubin by the liver, called physiologic jaundice. Bilirubin is a normal product that results in the destruction of red blood cells. It also can take on two possible forms, unconjugated and conjugated. Unconjugated bilirubin is lipid-soluble, whereas conjugated bilirubin is water soluble. Jaundice occurs when there is an increased amount of …show more content…
When visible light illuminates the skin, the bilirubin molecules absorb the photons of energy, in which the molecules then undergo isomerization. This new isomer of the bilirubin molecules is now able to be excreted by the body. As a result of this isomerization, the bilirubin molecules are more polar, allowing them to be excreted from the liver without undergoing conjugation by the liver. They are not also unable to cross the blood brain barrier of an infant. If jaundice is not treated, toxic accumulation of bilirubin can occur. Kernicterus, the occurrence of deep yellow stained neurons of the brainstem is a neurological complication that can occur.

Factors affecting the effectiveness of phototherapy

Irradiance: Irradiance is the light intensity, also known as the number of photons delivered per square centimeter of an exposed body surface. The higher the irradiance, the quicker the decline of bilirubin.

Distance from light: This is directly related to irradiance, in that the closer the light is to the infant, the higher the irradiance with

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