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Synthetic Blood Research Paper

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In the United states, a unit of blood is transfused every 3 seconds. (ncbi) This amount has been increasing at a much greater rate than that of blood donors. (ncbi) Blood products can be used to save the lives of many people who suffer from a variety of problems such as shock or trauma. Trauma can cause a huge loss of blood and without a blood transfusion many people will die before reaching surgery or even the hospital. Right now the only option available to save these patients life is a transfusion from blood or blood products like plasma that has been donated. This type of blood transfusion comes with a variety of risk, including transfusion transmitted diseases, donor shortage, short shelf life, refrigeration, and donor matching (ncbi) …show more content…
Synthetic blood can be superior to normal blood in that it has a long shelf like, it is filterable making it safer, it can be made in mass quantities, and there is no need for matching (ncbi) Some of the more popular types included oxygen carrying solutions, platelet substituets, and nanoparticles. There are two types of oxygen carrying solutions: hemoglobin based, perfluorocarbon based (ncbi) These are helpful because they can carry oxygen through the body helping with hypoxia. There are three sources that hemoglobin based solutions come from: human (polyheme), animal, and recombinant …show more content…
While the idea of a replacement for blood is not new, the actual products themselves are and come with many negative aspects. Many of the synthetic blood products will be able to provide a large supply that lasts long but they are very expensive and so far have been found to have a short duration of action. On a more cellular level, they can also cause macrophage damage, thrombocytopenia, high blood pressure, and gastrointestinal dsymobility. (ncbi) Another problem with these products is that they can affect some of the life saving blood tests that need to be performed giving false or inaccurate results. (ncbi) Some of them are also limited on who they can be used on. Polyheme, for example, can’t be given to young children and women who are pregnant.

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