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Alan R. Jacobs Case Summary

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This paper outlines a case study written by Alan R. Jacobs published to Neuroendocrinology.org. He reports of his patient, 40 year old female named Janet, whom was referred to him after experiencing symptoms of hypothyroidism and being treated accordingly with no effective results. Janet’s tests shown normal thyroid function, although she still experienced several symptoms of hypothyroidism, normal thyroid hormone treatment was ineffective. She was previously treated with high doses of Cytomel, which reduced the symptoms but also suppressed her TSH level and increased heart rate. Dr. Jacobs suspected peripheral resistance to thyroid hormone syndrome and treated Janet with increasing doses of Cytomel and a beta-blocker to help control her heart

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