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H Pylori Research Paper

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You Probably Have H. Pylori
Helicobacter Pylori or H. Pylori is a gastrointestinally thriving bacterium first discovered by Dr. Marshall and Dr. Warren in 1892 during examinations and cultures of stomachs of patients with gastritis and ulcers. It’s physiology and environment of choice both create a unique dichotomy which ultimately allows it the survive in the human body for, possible, the whole patient's lifetime. Furthermore, its epidemiology has enabled H. Pylori to seemingly go undetected as the cause for a variety of illness such as duodenal ulcer and stomach cancer. All of these factors have created a versatile pathogen.
Before the discovery of H. Pylori the conventional thought of bacteria was that none could live in the acidic environment …show more content…
Though it may live inside its host forever as asymptomatic there are diseases that may arise from the stomach lining being broken and the patient's immune system acting up. For instance, stomach and duodenal ulcers may arise in adult carriers of the bacteria who contracted it years before as a child. The germs can live in the body for years before symptoms start, but most people who have it will never get Ulcers. However, symptoms of those who do receive Ulcers include bloating, burping, not feeling hungry, nausea, vomiting, weight loss for no clear reason. Furthermore, ulcers can bleed into a patient's stomach or intestines creating symptoms such as stool that is bloody, dark red, or black, trouble breathing, dizziness or fainting, vomit that has blood or looks like coffee grounds, and severe, sharp stomach pain (WebMD). Another more serious disease caused by the Helicobacter Pylori pathogen is non-cardia gastric cancer. Some H. Pylori are carriers of a toxin called cytotoxin-associated gene A (cagA). They inject this toxin from a needle like appendage into the junctions where cells of the stomach lining meet. This toxin alters the structure of stomach cells and allows the bacteria to attach to them more easily. However, it suppresses needed proteins to the epithelial cells creating rapid reproduction of said cells. Furthermore, Gastric MALT lymphoma is a rare type of non-Hodgkin lymphoma that is characterized by the slow multiplication of B lymphocytes, a type of immune cell, in the stomach lining. This cancer represents approximately 12 percent of the extranodal (outside of lymph nodes) non-Hodgkin lymphoma that occurs among men and approximately 18 percent of extranodal non-Hodgkin lymphoma among women (Wu, 337–346). Normally, the lining of the stomach lacks lymphoid tissue, but development of this tissue is often stimulated in response to colonization of the lining by H. pylori. Only in rare cases does

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