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Muscle Contraction Case Study

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1. Without ATP, muscles cannot relax nor contract. During muscle contraction, an ADP and phosphate molecule is attached to the myosin head. The actin myofilaments’s active site are exposed because calcium binds to troponin during contraction. This binding causes the tropomyosin to move out of the way exposing the active site. The phosphate molecule attached to the myosin head is used, as energy, and released after it pulls the myosin head to the active site of the actin myofilament, which forms a bond called a cross-bridge. The connects myosin head uses the energy of the ADP molecule to slide pass the actin myofilament. This is a contraction. ADP is released after. Once released, ATP comes and binds the myosin head, this allows the myosin head …show more content…
The ATP molecule releases energy and breaks down to ADP and a phosphate molecule. This energy allows the myosin head to return to its upright position, allowing it to relax. Contraction needs ADP and phosphate, which comes from ATP. Relaxation needs ATP to release itself from the binding site of the actin myofilament.
2. A signal from the nervous system opens the gates for Calcium ions to flow through into the synaptic knob. The calcium ions stimulate the synaptic vesicles to release acetylcholine (Ach) into the synaptic cleft, binding to receptors on the sarcolemma. When two Ach bind to a receptor, it opens the gate and allows Na+ to flow into the ICF and K+ into the ECF. This then stimulates the voltage gated ion channels beside the receptors to open its gates that allow either K+ out or Na+ in, creating action potential. The action potential continues spreads in all direction until it reaches the T tubules, where it then enters the cell interior. From here, action potential opens the gates in the T tubules, which opens the channels in the sarcoplasmic reticulum. This causes calcium to flow out into the cytosol where it binds to the troponin of the thin filaments. This binding changes the shape of

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