...Company Information The Melanoma Research Foundation (MRF), was founded in 1996 by Diana Ashby. During a personal three year battle against melanoma, Diana had lost several friends to the disease, and became frustrated that there were no effective treatments being developed. Diana began researching for alternative therapies, and discovered that promising therapies were often halted due to lack of funding. She then founded MRF to raise money for research, but sadly, lost her light to the disease eight months later (MRF, 2015). In 2009, I became familiar with the MRF, following my personal battle with melanoma. The organization at that time was located in Hillsborough, NJ, and has since moved to Washington, D.C., as a strategy to strengthen their influence in legislation and finding for new treatments and therapies. Since then, the organization has spearheaded initiatives to accelerate drug therapies, established themselves as leaders in ocular melanoma awareness and research...
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...What is the cause of skin cancer? Stresses such as tobacco and radiation can cause cancer by damage to deoxyribonucleic acid (DNA) cells. DNA is the source of life which is stored inside the nucleus of every cell that makes up a living organism. To be able to fit inside a 10-micrometer average size cell, 10-meter long DNA has to be packed into a complex structure which is known as chromatin. Nucleosome is DNA wrapping around histone octamers and chromatin is form when nucleosomes in a nucleus compact together (Yu et al. 2011). At the chromatin level, it compacts to protect DNA from stresses after a short period of time (Interview with Dr. Michael Bergel 2015; unreferenced, see “Acknowledgements”). DNA fails to repair or kill itself (apoptosis) after being damaged which will causes DNA mutation. DNA mutation in a certain gene can make cells grow “out of control”. In human cells, the process of repairing DNA damage which occurs within chromatin is called Nucleotide Excision Repair (NER). Increasing age will decrease DNA ability to repair itself; this explains why a majority of cancer patients appear to be older adults. Ultraviolet radiation (UV radiation) is the main cause of skin cancer. Chromatin in skin cells after UV irradiation are found to...
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...Proceedings of the International Conference on Non-Ionizing Radiation at UNITEN (ICNIR 2003) Electromagnetic Fields and Our Health 20th – October 2003 22nd Recent Research on Mobile Phones Effects Dr. Abdullah AlOrainy Inst. of Electronics Research, KACST P. O. Box: 230471, Riyadh 11321, Saudi Arabia E-mail: alorainy@kacst.edu.sa ABSTRACT The use of mobile phones always accompanied by the issue of health implications for human. Previous research studies show no evidence of the impacts of mobile phones to human health. New studies suggest that mobile radiation might double the risk of developing cancer on the side of the head used, increase brain activity, can cause damage to nerves around ears and, more importantly, damages the BBB. Also new research shows that biological effects are possible without any warming of tissues which impose of the current radiation exposure levels. KEYWORDS Mobile Radiation, Health Effects INTRODUCTION There are now about 1 Billion mobile phones in use worldwide, and it is expected to reach 1.6B lines by year 2005. In many countries, penetration rates of more than %50 has been reached. At present, there are approximately 4.5 million GSM subscribers in Saudi Arabia and STC has commissioned Ericsson and Nokia to expand its GSM network to 5.5 million lines (~ %20 penetration rate). This wide use of mobile technology have often raise the question about if there are health implications for human. In fact, there are conflicting reports relating to possible...
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...Breast Cancer Tonia Maraden CM220-51 November 23, 2012 Breast Cancer Debra Wheeler is a wonderful person and a personal friend that works with me at my part time job. She is the Executive Assistant to the CEO. In January of last year, Debra Wheeler was diagnosed with Stage 2 breast cancer. She ended up having to have single mastectomy since the cancer was only in one of her breast. She then later had to have the breast the removed and reconstructed. The way they did it was take the skin and soft tissues from the belly and use it to reconstruct her new breast. Debra’s healthy body and her positive spirit helped her to beat the cancer, now she has been cancer free for a year. She is a very strong willed person and that is why I believe is the reason that she is still here today others have not been so lucky or gave up the fight too early. With this in mind, Debra has discovered along with many breast cancer survivors that the oral contraceptives for many years were a possible cause to the reason they were diagnosed with cancer. There are more than one reason has to why we should support breast cancer. Breast cancer is something that will or has affected us all in one way or another. I. Here are some statics on breast cancer: A. A woman is diagnosed with Breast Cancer every 2.5 Minutes. 1. Worldwide, breast cancer...
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...State Health Services Chapter 91. Cancer Subchapter A. Cancer Registry Effective Date: August 14, 2011 §91.1. Purpose. This subchapter implements the Texas Cancer Incidence Reporting Act, Health and Safety Code, Chapter 82. This legislation concerns the reporting of cases of cancer for the recognition, prevention, cure or control of those diseases, and to facilitate participation in the national program of cancer registries established by 42 United States Code, §§280e - 280e-4. Nothing in this subchapter shall preempt the authority of facilities or individuals providing diagnostic or treatment services to patients with cancer to maintain their own cancer registries. §91.2. Definitions. The following words and terms, when used in this subchapter, shall have the following meanings, unless the context clearly indicates otherwise. (1) Act--The Texas Cancer Incidence Reporting Act, Texas Health and Safety Code, Chapter 82. (2) Branch--Cancer Epidemiology and Surveillance Branch of the department. (3) Cancer--Includes a large group of diseases characterized by uncontrolled growth and spread of abnormal cells; any condition of tumors having the properties of anaplasia, invasion, and metastasis; a cellular tumor the natural course of which is fatal, including intracranial and central nervous system malignant, borderline, and benign tumors as required by the national program of cancer registries; and malignant neoplasm, other than non-melanoma skin cancers such as basal and squamous cell...
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...Introduction The aim of this paper is to discuss the role of the law and science in moving us towards a more sustainable future. This will be done with the aid of selected global environmental treaties. In order to achieve this aim, the paper is going to begin with an introduction which is going to define key concepts identified. The main body will embark on the discussion at hand. The main body will begin by outlining the role of the law generally and will move on to look at the role of science generally. Thereon selected global treaties will be discussed in relation to their respective roles both at law and science. Lastly but not the least an elaborate conclusion will be given. Definition of Key Terms Environment: Environment refers to the totality of the surroundings within which humans live and exploit resources for their welfare and development. Main Body In order to effectively challenge problems that pose a threat to the earth, there is need for an effective approach which is backed by robust scientific evidence. This would ultimately usher into place a new and more powerful environmental law. In order to appreciate the relationship between the law and science, there is need for understanding of their respective roles towards the achievement of a more sustainable future. The Role of the Law The law has a fundamental role to play in the movement of protecting the environment towards a more sustainable future. In most jurisdictions in the absence of constitutional...
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...Mobile Telecommunications and Health Review of the current scientific research in view of precautionary health protection April 2000 ECOLOG-Institut Translated by Andrea Klein Mobile Telecommunications and Health Review of the Current Scientific Research in view of Precautionary Health Protection Commissioned by T‐Mobil DeTeMobil Deutsche Telekom MobilNet GmbH Authors Dr Kerstin Hennies Dr H.‐Peter Neitzke Dr Hartmut Voigt With the support of Dr Gisa‐Kahle Anders ECOLOG‐Institut für sozial‐ökologische Forschung und Bildung gGmbH Nieschlagstrasse 26 30449 Hannover Tel. 0511‐92456‐46 Fax 0511‐92456‐48 Email mailbox@ecolog‐institut.de Hannover, April 2000 Contents 1 1 1.1 1.2 2 Introduction 1 3 New Technologies and Precautionary Health Protection Terms of Reference and Structure of the Review 5 2.1 2.2 3 Collating and Interpreting the Scientific Data (Methodology) 5 5 Primary Reciprocal Effects between High Frequency Electromagnetic Fields and Biological Systems (Biophysical and Biochemical Processes) 3.1 3.2 3.3 3.4 3.5 4 Thermal Effects 3.1.1 Effects of Homogenous Warming 3.1.2 Microthermal Effects Direct Field Effects 3.2.1 Effects from the Electrical Component of the Electromagnetic Field 3.2.2 Effects from the Magnetic Component of the Electromagnetic Field ...
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...Review The Controversy about a Possible Relationship between Mobile Phone Use and Cancer Michael Kundi Institute of Environmental Health, Medical University of Vienna, Vienna, Austria oBjective: During the last decade, mobile phone use increased to almost 100% prevalence in many countries of the world. Evidence for potential health hazards accumulated in parallel by epidemiologic investigations has raised controversies about the appropriate interpretation and the degree of bias and confounding responsible for reduced or increased risk estimates. data sources: Overall, I identified 33 epidemiologic studies in the peer-reviewed literature, most of which (25) were about brain tumors. Two groups have collected data for ≥ 10 years of mobile phone use: Hardell and colleagues from Sweden and the Interphone group, an international consortium from 13 countries coordinated by the International Agency for Research on Cancer. data synthesis: Combined odds ratios (95% confidence intervals) from these studies for glioma, acoustic neuroma, and meningioma were 1.5 (1.2–1.8); 1.3 (0.95–1.9); and 1.1 (0.8–1.4), respectively. conclusions: Methodologic considerations revealed that three important conditions for epidemiologic studies to detect an increased risk are not met: a) no evidence-based exposure metric is available; b) the observed duration of mobile phone use is generally still too low; c) no evidence-based selection of end points among the grossly different types of neoplasias is possible...
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...Identify and describe the categories of value creation on which Best Value currently relies most. Identify and describe the categories of value creation on which Best Value currently relies most Straight commission is a “pay for performance plan” where monetary compensation is strictly tied to the results achieved by the salesperson. It is best used when maximum time is provided for the salespeople to sell while non-selling tasks are minimized. Ordinarily, commissions are in direct correlation and proportionate to the value or volume of completed sales transactions made by the salesperson. Since financial compensation plans are offered as motivational incentives to inspire and energize the sales force to achieve greater results, it is assumed that the higher commissions earned from performance will also produce higher profits for the company (Hoffman, 2007). Because straight commissions are directly paralleled with performance outcome, it is believed that salespeople are motivated to attain a higher level of selling effort (Johnston & Marshall, 2009). The advantage of paying employees on a straight commission basis is that they provide maximum incentives for the salesperson. Straight commissions tend to reward high achievers while discouraging poor performance from salespeople with low productivity. For the company, higher commissions can be used to direct the sales team toward certain products that may produce a higher profit. In addition, it limits the amount of working...
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...1. Introduction This is the final project of the Course Named: Investment & Portfolio Analysis. The purpose of this project is to examine thoroughly if the CAPM holds true in the emerging capital market of Pakistan. Tests are conducted for a period of five years (2005-2009), which is characterized by intense return volatility (covering historically high returns over the examined period). 2.1. Karachi Stock Exchange * Incorporated on March 10, 1949 * Premier Stock exchange of the country * Started with 5 companies that had a paid up capital of Rs. 37 million. * Trading was done through an open-out-cry system * The first index was the KSE 50 Index * Exchange owned by 200 members * 652 companies listed * 4 indices * Modern Risk Management System a. Var Based Margin b. Pre Trade Margin Verification * KSE is FIX Compliant * Electronic Trading through KATS * Market capitalization*: US $ 26.04 billion * Publicly Listed Company with strategic investor * Products to include: a. Options b. ETFs c. Tradable Sector Indices d. Debt Market Trading * Broad based investor participation * Cross border listings of companies * Opening up of branches in other cities and in the region 2.2.1. Definition A stock exchange, share market or bourse is a corporation or mutual organization which provides facilities for stock brokers and trader s, to trade company stocks and other...
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...title and authorship are not allowed without the approval of the responsible editor. In such a case, please contact us for futher advice. · If we do not receive your corrections within 48 hours, we will send you a reminder. · The final versions of your article will be published around one week after receipt of your corrected proofs. Jaworek et al. Orphanet Journal of Rare Diseases 2012, 7:44 http://www.ojrd.com/content/7/1/44 1 2 3 4 5 6 7 RESEARCH Open Access Molecular genetic studies and delineation of the oculocutaneous albinism phenotype in the Pakistani population Thomas J Jaworek1, Tasleem Kausar2, Shannon M Bell1, Nabeela Tariq2, Muhammad Imran Maqsood2, Asma Sohail2, Muhmmmad Ali2, Furhan Iqbal2, Shafqat Rasool3, Saima Riazuddin1,4,5,6, Rehan S Shaikh2,8* and Zubair M Ahmed1,2,4,5,6,7* 8 Abstract 9 Background: Oculocutaneous albinism (OCA) is caused by a group of genetically heterogeneous inherited defects that result in the loss of pigmentation in the eyes, skin and hair. Mutations in the TYR,...
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...among the records. Within the research several popular MDSS’s are analysed in order to determine the most common data mining algorithms utilized by them. Three algorithms have been identified: Naïve Bayes, Multilayer Perceptron and C4.5. Prior to the very analyses the algorithms are calibrated. Several testing configurations are tested in order to determine the best setting for the algorithms. Afterwards, an ultimate comparison of the algorithms orders them with respect to their performance. The evaluation is based on a set of performance metrics. The analyses are conducted in WEKA on five UCI medical datasets: breast cancer, hepatitis, heart disease, dermatology disease, diabetes. The analyses have shown that it is very difficult to name a single data mining algorithm to be the most suitable for the medical data. The results gained for the algorithms were very similar. However, the final evaluation of the outcomes allowed singling out the Naïve Bayes to be the best classifier for the given domain. It was followed by the Multilayer Perceptron and the C4.5. Keywords: Naïve Bayes, Multilayer Perceptron, C4.5, medical data mining, medical decision support Chapter 1: Introduction to the Study Introduction Thesis Structure Study Overview Background of the research Focus Area & Motivation Aims and Objectives Research Problems Motivation and Challenges Thesis Outline Intellectual Challenge Justification for the Research Methodology Conclusion Chapter...
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...A kid with Hepatitis A can return to school 1 week within the onset of jaundice. 2. After a patient has dialysis they may have a slight fever...this is normal due to the fact that the dialysis solution is warmed by the machine. 3. Hyperkalemia presents on an EKG as tall peaked T-waves 4. The antidote for Mag Sulfate toxicity is ---Calcium Gluconate 5. Impetigo is a CONTAGEOUS skin disorder and the person needs to wash ALL linens and dishes seperate from the family. They also need to wash their hands frequently and avoid contact. positive sweat test. indicative of cystic fibrosis 1. Herbs: Black Cohosh is used to treat menopausal symptoms. When taken with an antihypertensive, it may cause hypotension. Licorice can increase potassium loss and may cause dig toxicity. 2. With acute appendicitis, expect to see pain first then nausea and vomiting. With gastroenitis, you will see nausea and vomiting first then pain. 3. If a patient is allergic to latex, they should avoid apricots, cherries, grapes, kiwi, passion fruit, bananas, avocados, chestnuts, tomatoes and peaches. 4. Do not elevate the stump after an AKA after the first 24 hours, as this may cause flexion contracture. 5. Beta Blockers and ACEI are less effective in African Americans than Caucasians. 1. for the myelogram postop positions. water based dye (lighter) bed elevated. oil based dye heavier bed flat. 2.autonomic dysreflexia- elevated bed first....then check foley...
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...This report is to be submitted as "2008 Korea Pharmaceutical Industry Directory" as part of the "Actual analysis of Korean pharmaceutical Industry", Korea Health Industry Development Institute(KHIDI)'s own project. December 2008 ￭ ￭ ￭ • ⅰ Chapter 1. Outline of The Project 1. Objectives and Background of Investigation ◦The existing directory book has indicated limitations in promoting Korean pharmaceutical industry internationally or domestically, failing to offer practical help. ◦For this reason, this investigation is to have a thorough grasp of ranges of business and current status of investments and technology by pharmaceutical and companies to utilize and in to strengthen their industrial by competitiveness promoting them overseas collecting and offering basic data needed for promoting transfer of technology with home and abroad institutions. ◦Also, necessity for systematic and detailed data of industrial current status that can be utilized by companies who are making commitment for the development of pharmaceutical industry. 2. Targets and Contents of Directory Book 1) Targets for directory book •Korean Pharmaceutical companies: 81 companies. 2) Contents of directory book •Investigation items 3. Method and Way for Utilization 1) Method □ Ways to select investigation targets and to promote them were developed through consultation from consultation committees and domestic pharmaceutical companies (including unlisted ones) ◦Investigated...
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...Contents Preface Acknowledgments Introduction 1 BRAIN POWER Myth #1 Most People Use Only 10% of Their Brain Power Myth #2 Some People Are Left-Brained, Others Are Right-Brained Myth #3 Extrasensory Perception (ESP) Is a Well-Established Scientific Phenomenon Myth #4 Visual Perceptions Are Accompanied by Tiny Emissions from the Eyes Myth #5 Subliminal Messages Can Persuade People to Purchase Products 2 FROM WOMB TO TOMB Myth #6 Playing Mozart’s Music to Infants Boosts Their Intelligence Myth #7 Adolescence Is Inevitably a Time of Psychological Turmoil Myth #8 Most People Experience a Midlife Crisis in | 8 Their 40s or Early 50s Myth #9 Old Age Is Typically Associated with Increased Dissatisfaction and Senility Myth #10 When Dying, People Pass through a Universal Series of Psychological Stages 3 A REMEMBRANCE OF THINGS PAST Myth #11 Human Memory Works like a Tape Recorder or Video Camera, and Accurate Events We’ve Experienced Myth #12 Hypnosis Is Useful for Retrieving Memories of Forgotten Events Myth #13 Individuals Commonly Repress the Memories of Traumatic Experiences Myth #14 Most People with Amnesia Forget All Details of Their Earlier Lives 4 TEACHING OLD DOGS NEW TRICKS Myth #15 Intelligence (IQ) Tests Are Biased against Certain Groups of People My th #16 If You’re Unsure of Your Answer When Taking a Test, It’s Best to Stick with Your Initial Hunch Myth #17 The Defining Feature of Dyslexia Is Reversing Letters Myth #18 Students Learn Best When Teaching Styles Are Matched to...
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