...Problem Solution: Gene One University of Phoenix March 26, 2007 Problem Solution: Gene One Introduction Gene One entered the biotech industry with groundbreaking gene technology that eradicated disease in tomatoes and potatoes. As a result, farmers no longer needed to use pesticides when growing these plants and consumers were pleased to buy homegrown products untainted by chemicals. The win-win situation helped Gene One grow to a $400 million company in just eight short years. Sharply rising stock indices on Wall Street indicate a growing interest in biotechnology and leadership changes at the Food and Drug Administration are further enhancing investor confidence in the industry. At Gene One, the CEO and his Board believe that in order to keep pace with demand and realize conservative annual growth targets of 40 percent, Gene One is going to have to go public within the next three years. It is their hope that implementing it will help Gene One realize its growth targets, establish the company as a strong competitor and show Wall Street that Gene One has the leadership and organizational capabilities to succeed as a public entity. In this paper I will analysis some issues and opportunities that Gene One is facing as well as present a situation analysis defining the problems that Gene One needs to address. I will also analysis alternative and optimal solutions as well as identify the risk that in involved. Once all alternatives have been clear I will recommend...
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...Running head: PROBLEM SOLUTION: GENE ONE Problem Solution for Gene One University of Phoenix MBA 520 – Transformational Leadership Problem Solution for Gene One Change is inevitable in any organization; however, there are a myriad of approaches toward that change and the individuals involved. Change relates directly to organizational behavior and leadership style. This problem analysis and suggested solution will look at a scenario entitled Gene One and will explore the challenges facing the CEO and the changes facing the company and its employees. This analysis will review a number of leadership style issues in addition to organizational culture, knowledge management, emotional intelligence, and knowledge management. Situation Analysis Issue and Opportunity Identification Change is, and never has been as easy to accept, as the change agent would prefer. Niccolo Machiavelli said, “There is nothing more difficult to take in hand, more perilous to conduct, or more uncertain in its success, than to take the lead in the introduction of a new order of things” (Kaplan, J. ed. 1992, p. 136). Several areas related to organizational development and leadership style are evident in the scenario. Internal communication or lack thereof can make or break an organization in transition. At Gene One, the process has not been particularly effective to date creating tension not only within management but also throughout the organization. Management has a unique opportunity...
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...Problem Solution: Gene One Introduction Good Sport is a company that values innovation, quality, relationships, and customer satisfaction. With health conscious initiatives and groundbreaking innovation, the company now realizes a successful business in sports fitness. Founded over fifteen years ago by former athlete, Jason Poole, good sport has established itself in promoting healthy living through uniquely compact and safe exercise equipment that is high in consumer demand. The company has been very successful in developing, marketing, and selling new products over the past few years. This success can be primarily attributed to the strong organizational structure—including its organizational culture and corporate values—that is grounded in the company vision and imbedded in the execution of the company’s mission throughout all levels. While the company has had issues of internal conflicts and ineffective leadership; nevertheless, the organizational structure of good sport has not been a stumbling block impeding upon progress. As a result, Good Sport can be considered a stable and thriving company—even in the midst of leadership and/or organizational change. This paper will further describe the organizational structure of Good Sport and examine its cultural environment—to include a description of the subcultures of two of its department. The analysis will include a look at the departmental leadership—examining the effectiveness and influence over these groups. ...
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... The Guillermo Furniture Store Orlando Hopper ACC/561 – Accounting University of Phoenix (Instructor’s Name) October 4, 2010 The Guillermo Furniture Store Guillermo Furniture Store is one of the largest furniture company’s in North America, which is located in Sonora Mexico. Guillermo is a very establish and successful businessmen. Guillermo over the last several years has specialized in making handcrafted premium grade products. Guillermo belief’s is in the quality of his product and prices. Guillermo has been able to charge high-end prices and carry a low labor cost and budget. Guillermo is able to purchase his supplies at low cost which are from Mexico. Till recent, Guillermo furniture company was the only one in his area. With a foreign competitor entering the furniture market and offering the same furniture and selling for a less price which is using high-tech equipment to build their furniture and has threaten Guillermo’s business, which has felt some decline in the result of competition. Guillermo will have to make some important decisions that can affect his company’s future to stay competitive in the furniture market. Decision Making process Guillermo...
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...In this paper I will attempt to help Gene One solve their current problems that they are experiencing as a result of poor planning by management with a new IPO strategy. Although I believe that they were looking out for the company’s/employees’ best interest, the lack of a solid game plan has led us to this point where the working relationship between management has failed. While attempting to uncover the optimal solution I will look at the factors that should be considered when evaluating all options. My hopes are to bring to light why one solution is better than the next as it relates to the vision and goals of the company. This will be done by examining evidence from outside sources that have been through similar situations. This solution will be centered on transformational leadership and organizational culture. By identifying the primary causes of the failed strategy’s implementation, I will dissect and attempt to salvage the IPO strategy that Gene One will still need to carry out. In reading this scenario, one thing obvious from the onset; the senior leadership team at Gene One is not all on the same page. Anytime there is a culture change within an organization there will be resistance by some to change. In the case of Gene One they are no more immune than any other company. Evidence of this could be seen from the interactions of Teri and Michelle at the 1st leadership meeting after the board’s approval of the IPO plan. “What’s the matter, Michelle? Not finding enough...
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...Running head: PROBLEM SOLUTION: GENEONE Problem Solution: Gene One The basis for my investigation of the problem in the Gene One scenario is the fact that Gene One’s CEO, Don Ruiz and the Board of directors believes that if the company is to continue its growth of 40% each year, the company will have to go public with an initial public offering (IPO) within the next three years. The purpose for this paper is to review Gene One’s decision to become a public company. Taking Gene One public would be a new venture for the senior team members, who realize that, collectively, they have zero experience with IPOs. This paper looks at the issues and opportunities Gene One is facing, stakeholder’s perspective and ethical dilemma, the end-state goals, alternative solutions, a risk assessment and the optimal solution, and last implementation of the plan. Situation Analysis Issue and Opportunity Identification Gene One is a company that entered the biotech industry with groundbreaking gene technology that eradicated diseases in tomatoes and potatoes. In just eight short years, the company grew into the $400 million company that it is today. Past events that have led to Gene One current issues and opportunities are the fact that the company has grown at such a rapid pace that it outgrowing itself. Further, an increase in stock prices is indicative of the growing interest in the biotech industry. Don Ruiz, the company’s CEO, and the board of directors believes that if the company...
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...is also one of the most used tools used in modern biotechnology. It has allowed for a lot of genetic engineering advances. Scientists can design and build DNA containing genes they want and then transfer these genes into bacterial cells that they can get to express those genes. This is a very basic technique that is used on a daily basis in a molecular biological laboratory. This is based on the natural function of a plasmid: to transfer genetic information vital to the survival of the bacteria. Transformation is an example of horizontal gene transfer. There are three mechanisms for horizontal gene transfer in bacteria. Conjugation is the transfer of DNA from one cell to another through conjugation pili. Transduction is the transfer of genes between bacterial cells using a bacteriophage (a type of virus). Transformation is the ability of cells to take up freely floating DNA found in the environment. Bacterial cells that are able to take up free-floating DNA from the environment are called competent cells. Bacteria are not always competent. When growth conditions are optimal, most bacteria cannot uptake DNA. In most cases, in response to some stimuli (such as stressor starvation), a cell can turn on the genes that allow it to become competent. In nature, as bacterial cells die, their cells are lysed, spilling their plasmid DNA into the environment. The DNA chromosome is broken up into chunks that float freely in the environment. A competent cell could take up one or more...
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...unpleasant side effects. The SIP-30 gene is a candidate gene for involvement in neuropathic pain. When neuropathic pain is present, SIP-30 levels rise indicating some cause and effect relationship. Transposons are mobile genetic elements that move around within a genome and integrate randomly, in a mechanism similar to some viruses. The PiggyBac transposon, derived from the cabbage looper moth Trichoplusa ni, is a particularly useful transposon, with many features that make it an ideal vector for gene therapy research. Plasmid vectors will be constructed, one carrying the SIP-30 gene, and another carrying antisense SIP-30 in the PiggyBac vector, in order to deliver the genes into mouse nerve cells. This is hypothesized to increase and decrease the expression of neuropathic pain respectively. The gene will be delivered through intrathecal injections into the mouse intrathecal fluid of the spinal cord. If successful, this research can have serious implications for future human gene therapy to treat neurological disorders, using the PiggyBac vector as the gene delivery system. Introduction: Features of the PiggyBac Transposon: Transposons are mobile genetic elements that move around within a genome and integrate randomly, in a mechanism similar to some viruses. The PiggyBac transposon, derived from the cabbage looper moth Trichoplusa ni, is a particularly useful transposon, with many features that make it an ideal vector for gene therapy research. The PiggyBac transposon...
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...Running head: GAP ANALYSIS: INTERSECT INVESTMENTS Gap Analysis: Gene One Stacy Starkes University of Phoenix May 17, 2010 Gap Analysis: Intersect Investments Gene One is a ground-breaking Biotech organization that has been faced with many issues. The organization has been forced to expand at a rapid rate to meet the organizational goals of becoming one of the leading organizations in the biotech industry. In order to compete with the ever increasing biotech industry, the CEO and the board of directors believe that going public within the next three years would be beneficial for the organization. By making the appropriate choices of becoming a publically traded organization, Gene One will bark upon a journey that will help them to revolutionize and to use cutting edge technology of eliminating pesticides on tomatoes and potatoes to meet the organizational goals. The rapid growth rate took the organization from a small $2 million start-up company to more than a $400 million in annual sales. Therefore, by implementing an IPO strategy and implementing other strategic goals will help fulfill the organizations growth target and prove the organization is worthy of its capabilities. In addition, the method of benchmarking can help Gene One to succeed and enable the organization to find the necessary solutions to the most pressing and immediate issues. According to The Benchmarking Exchange (2010), “Benchmarking is the process of measuring an organization's internal processes...
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...DNA with foreign pieces of DNA, pGLO, that causes expression of an ampicillin resistant gene, and see the effects it has on bacterial growth in presence of the antibiotic, ampicillin. We inserted pGLO DNA into the genome of the bacteria through the use of inoculation loops, Laurel Broth, transformation solution, and procedures such as heat shock and incubation. This experiment involved four bacterial agar plates, two of which we genetically transformed (experimental groups; +pGLO LB/amp/ara and +pGLO LB/amp), and two of which we did not genetically transform and were control plates (-pGLO LB and -pGLO LB/amp/). Out of the two genetically transformed bacteria, only the bacteria containing arabinose sugar (+pGLO LB/amp/ara) initiated expression of the GFP (Green Fluorescent Protein) gene, causing the bacterial...
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...Gene One: Problem Solution and Defense Gene One is a privately owned biotechnology company who is attempting an initial public offering (IPO). During this transition, opportunities within Gene One‘s organizational structure have been made more eminent. This paper uses the Problem Based Learning model the concepts of transformational leadership and organizational culture will be applied to the current internal issues faced by Gene One in the areas of team dynamics, knowledge and leadership style. Gene One is lead by Don Ruiz who has surpassed expectations during its 8-year growth. Don is an intrinsic part of a 5-member team who built the Gene One out of a 2 million-dollar investment. Don’s goal is to position Gene One as an industry leader. In order to acquire large amounts of capital for advanced research and superior product development to meet consumer demand and a grow by 40% per year, Gene One board of directors have decided on an initial public offering (IPO) within a 36 month deadline. Describe the Situation Issue and Opportunity Identification Gene One has several opportunities within the organizations. These opportunities are organizational culture, teamwork, and leadership. A company’s organizational culture is “the basic pattern of shared assumption, values, and beliefs governing the way employees within an organization think about and act on problems and opportunities,” (McShane and Von Glinow, 2005). Gene One must understand how employees' attitudes, feeling, and...
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...Gene therapy is the transplantation of regular/functioning genes to replace abnormal genes. Replacing the defective genes can potentially correct genetic disorders. This procedure is fairly new and illegal in the United States; therefore, causing a controversy in the genetic department of sciences. In the article, “Controversial gene therapy might help women have healthy children” posted in The Washington Post, explains the positives that can come from this experimental solution and also the negative consequences. The focal point of the article is discussing a specific issue with the mitochondria of women’s egg cells. The mitochondria are the energy powerhouses of the cell that synthesizes all of the cell’s adenosine triphosphate (ATP). The...
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...Apollo 13- Leadership during a crisis Lessons learned from Gene Kranz Introduction: Every employee of NASA should known the tragic event of Apollo 13; At that time in 1970 the three astronauts James Lovell, Fred Haise and Jack Swigert had to abort their mission to flight to the moon due to an explosion of an oxygen tank. They had to fight against, carbon dioxide, coldness, a lack of energy and the almost certain death. Despite of a distance of 205,000 miles the three men made it back to earth alive in the Lunar Module Aquarius (Lovell et al. 2006). This was only possible with the help of the Mission Control and the Flight Director Gene Kranz which worked together as an excellent team and came up with a richness of ideas to save the lives of the astronauts. Although it was one of the darkest and most tragic missions of NASA, it also can be learned a lot from this crisis. Apart from the technical knowledge which has been obtained from Apollo 13, a lot of conclusion can be made for leaders. Even with the best technology, it would not have been possible to bring the crew home safely, if not such a strong leader like Gene Kranz have led to rescue of Apollo 13. What lessons can be learned from his leadership style and decisions for future NASA projects will be analyzed and explained from a psychological point of view in this report. Recommendations for action: In many NASA projects, it always comes back to stressful situations, where quick decisions must be made which have...
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...EXAMINATION OF THE TAS2R38 GENE AND ITS SPECIFIC NUCLEOTIDE DIFFERENTIATIONS TO DETERMINE ABILITY TO TASTE PHENYLTHIOCARBAMIDE INTRODUCTION Although humans are essentially genetically identical as a whole, there are some minute variances in our gene coding that allow for differences in our interactions with the world. These genetic modifications may have extensive detrimental effects, small effects, or no apparent effect at all. A few of these alterations can even affect our senses. In this lab, we examine how a discovery by a scientist gives us insight into how a relative dissimilarity between humans can affect the ability or inability to taste certain chemicals. Scientist Arthur Fox learned that the chemical phenylthiocarbamide, or PTC, could be tasted by certain people while others could not (Dolan DNA Learning Center 2006). When this was revealed, it was inferred that the ability or inability to taste this substance may be genetically related. It was also possible that there was a specific gene that coded for this capability. The gene that was found to encode for the capacity to taste PTC is named the TASR38 gene (Dolan DNA Learning Center 2006). However, it is not just the gene itself that causes differences in the ability to taste this substance, but the differences of coding within certain locations of this gene. These distinctions in gene coding across human populations at nucleotide positions 145, 785, and 886 are called single nucleotide polymorphisms (SNPs)...
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...additional copies of the gene responsible for the fluorescence are needed. Perform the Polymerase Chain Reaction (PCR) and analyze the PCR reactions via agarose gel electrophoresis. NOTE: Read and all the instructions carefully before starting your experiment. Facilitators will guide you on the use of PCR machine and agarose gel electrophoresis. Be cautious when there is a need to handle items/equipments and the hazardous reagent, Ethidium Bromide (EB) in the EB room. Materials: Agarose gel electrophoresis set DNA ladder (marker) DNA loading dye DNA samples (labelled as DNA 1 and DNA 2; DNA 2 is obtained from P3) Deionised water Ice in tub Biohazard bin Disposable pipette tips Gloves Microcentrifuge (table top) Micropipettes (P1000, P100, P20) Microcentrifuge tubes (1.5ml) Paper Towels PCR machine PCR master mix (Taq Polymerase, MgCl2, dNTPs, buffer) Primers (labelled as Primer 1 and Primer 2) Methods: LAB 1: AM session (9.15am to 12noon) Part A: The Polymerase Chain Reaction (PCR) As a team, you will be using TWO DNA samples to perform TWO PCR reactions; DNA 1 will be given and DNA 2 which is obtained from your P3. NOTE: If you have TWO DNA samples from P3, choose the ONE with better purity or quantity. 1. Refer to Table 1 and complete the components and volumes needed to make PCR master mix. 2. For TWO PCR reactions, you need to prepare PCR master mix for 2.5 reactions (on ice). Pipette the solutions 1, 2, 3, 4 into a sterile...
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