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Epigenetic Changes In Early Life

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Epigenetics is the study of chemical changes that alter the genome and lead to a resultant change in expression of the genes. These changes may result in detrimental effects, especially in an individual's early life, when most organs are developing. Epigenesist brings such changes in development because it will lead to expression of undesired proteins from the genome which the core requirement for phenotypic expression (Mitchell et al., 2013). After the process, the genomes formed will be different from the usual ones hence a different protein will be expressed by the affected cell; and this may be an adverse effect. The epigenetics video shows how various chemical modifications occur to the genome, interacting specifically with DNA, and the …show more content…
Such twins are different in phenotypic aspects such as general conduct, health, and their growth rate. It is due to such observable differences that some researchers ventured into the field of human epigenetics, to find out the cause of how similar genes can lead to different outcomes. The answer has been discovered in the study of epigenetics which is defined in the articles as chemical changes that occur in the gene and alter its molecular physiology (Powledge, 2015). Such changes are associated with physiological, cognitive and behavioral differences observed in individuals, even if they are identical twins. Epigenetics research in humans is mostly done during the early stages of development so as to detect changes in behavior development, hence the term behavioral epigenetics. Under these studies, the environment also has a vital role to play in determining he perception implied by the brain cells. Epigenetics research has established various chemical changes that occur in the genome and lead to the expression of different proteins (Powledge, …show more content…
These changes lead to a resultant altered change in the way the affected genes are expressed, although the nucleotide sequences remain unchanged. The changes brought about by these processes may continue being expressed at various stages of cell division hence, the traits shown can be hereditary (Shaughnessy et al., 2014). During methylation of a DNA sequence, methyl groups (CH3) are found attached to the sequence, and this leads to a change in the physiology of the sequence, even if the bases remain the unchanged (Gentilini et al., 2013). These alterations are observed during the transcription process that leads to translation and further expression of proteins. Such effects are seen when methylation occurs at the promoter region that initiates transcription. On the other hand, histones are proteins around which DNA is wound, and they are essential regulating gene expression. Modifications of these proteins may lead to epigenesis whereby there is unregulated protein expression (Walker, Laferla, Oddo and Brewer, 2013). Epigenetics is, therefore, an essential component of learning to understand the effects of environment on psychology, while dwelling on the understanding of the human genome (Guthman & Mansfield,

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