...are derived from plants that have been used by traditional medical practitioners (Cragg and Newman, 2005). It is a fact that traditional systems of medicine have become a topic of global importance. African countries are at a stage where traditional medicine is considered more for its capacity to generate other medicine than for its own sake. In many cases research undertakings and the commercial use stemming from that research have always relied on information provided by the local communities and, in many instances, have hardly benefited from the research results (Rukangira, 2004) . In Africa, traditional healers and remedies made from plants play an important role in the health of millions of people. (Rukangira, 2004). Typically, studies on the medicinal plants such as Alstonia boonei have focused on the bioactivity of its chemical constituents, ethnobotany, pharmacology, and taxonomy. However, a comprehensive or systematic review on the plant is lacking. Furthermore, in much of the older literature concerning West Africa, the name Alstonia congensis has been erroneously used for Alstonia boonei. Consequently, this paper examined the effect of aqueous bark extracts of Alstonia boonei on the haematological parameters of male wistar abino rats. 1.2 LITERATURE REVIEW 1.2.1 Classification Alstonia comprises about 40 species and has a pantropical distribution. There are about twelve species of the genus Alstonia. Alstonia boonei De Wild belongs to the family Apocynaceae. The...
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...can now use in this technology because of two reasons: (1) the mouse is the most genetically manipulated mammal in the world and (2) it shares much of its genetic material with humans (and other mammals) which means that experimental findings in mice will often be directly relevant to conditions in humans. The paper focuses on the controversies and challenges in Gene Knockout Technology – an article/blog entitled “Sickle Cell Disease cured by Gene Knock-out”. Switching off a single gene can help treat sickle cell disease or sickle cell anemia (a chronic, usually fatal anemia marked by sickle-shaped red blood cells, occurring almost exclusively in Black people of Africa or of African descent, and characterized by episodic pain in the joints, fever, leg ulcers, and jaundice. The disease occurs in individuals who are homozygous for a mutant hemoglobin gene) by keeping the blood forever young. The illness is caused by a mutant form of adult haemoglobin, but not by fetal haemoglobin. Targeting BCL11A, the gene responsible for the body's switch-over from fetal to adult haemoglobin, effectively eliminates the condition in mice. The mutant form of adult haemoglobin forms long sticky chains inside red blood cells. The cells containing these chains can clog small blood...
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...this paper, I will be looking at and reviewing the research literature that is available concerning sickle cells disease. I chose this topic for a reason that is close to my heart; I have an eight month old infant who has been diagnosed with sickle cell disease. As a professional, I am concerned with the ways that we as nurses can contribute to providing quality care in response to clients presenting with this specific disease. As a person, I am on the other side of the health promoting, family based care relationship that I am used to in my practice; I now really appreciate how important it is for nurses to provide education, information, teaching and training to parents and clients in response to an illness like sickle cell. In a way, therefore, I am serving both as teacher and student here, as I develop knowledge and collect evidence that I will use as both a nurse and as a concerned parent seeking to understand a disease that my child has been diagnosed with. This literature review supports the argument that nurses can play an important role in promoting quality care for clients and families coping with sickle cell disease, once a strong understanding of this disease and the nurse’s role in responding to it is achieved. This, therefore, is the goal of this literature review. Gale’s “Health Reference Centre Academic” database was used for the research. In fact, a very simple search resulted in the obtainment of all six of the quality, peer reviewed, scholarly research articles...
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...Centre Number For Examiner’s Use Candidate Number Surname Other Names Examiner’s Initials Candidate Signature Question General Certificate of Education Advanced Subsidiary Examination June 2009 Mark 1 2 3 Biology Unit 2 BIOL2 4 5 The variety of living organisms 6 Thursday 4 June 2009 1.30 pm to 3.15 pm 7 8 9 For this paper you must have: G a ruler with millimetre measurements. You may use a calculator. TOTAL Time allowed G 1 hour 45 minutes Instructions G G G G G G Use black ink or black ball-point pen. Fill in the boxes at the top of this page. Answer all questions. You must answer the questions in the spaces provided. Answers written in margins or on blank pages will not be marked. You may ask for extra paper. Extra paper must be secured to this booklet. Do all rough work in this book. Cross through any work you do not want to be marked. Information G G G G The maximum mark for this paper is 85. The marks for questions are shown in brackets. Quality of Written Communication will be assessed in all answers. You will be marked on your ability to: – use good English – organise information clearly – use accurate scientific vocabulary where appropriate. (JUN09BIOL201) APW/Jun09/BIOL2 BIOL2 2 Areas outside the box will not be scanned for marking Answer all questions in the spaces provided. 1 The diagram shows some of the large blood vessels in a...
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...------------------------------------------------- KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY,KUMASI. ------------------------------------------------- ------------------------------------------------- COLLEGE OF HEALTH SCIENCES ------------------------------------------------- ------------------------------------------------- SCHOOL OF MEDICAL SCIENCES ------------------------------------------------- ------------------------------------------------- DEPARTMENT OF COMMUNITY HEALTH ------------------------------------------------- ------------------------------------------------- BIRTHWEIGHT OF NEWBORNS IN RELATION TO THE NUTRITIONAL STATUS OF PREGNANT WOMEN IN THE ATWIMA NWABIAGYA DISTRICT OF ASHANTI REGION OF GHANA. ------------------------------------------------- ------------------------------------------------- ------------------------------------------------- A DISSERTATION SUBMITTED TO THE SCHOOL OF GRADUATE STUDIES, ------------------------------------------------- KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY, KUMASI IN ------------------------------------------------- PARTIAL FULFILMENT OF REQUIREMENTS FOR THE AWARD OF MASTER OF ------------------------------------------------- PUBLIC HEALTH (MPH) DEGREE IN POPULATION AND REPRODUCTIVE HEALTH. ------------------------------------------------- ------------------------------------------------- ...
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...EDSST 1 RESEARCH AND ACTION PLAN SUBMITTED BY: ABIGAIL A. DELA SALDE SST 1 STUDENT CHRISTINE MAE SALAS SST 1 STUDENT LAVIÑA ALCOSIBA SST 1 STUDENT SUBMITTED TO: PROF. JACKSON SISON ED SST 1 PROFESSOR INTRODUCTION This research enhances the idea of every student on how to deal different economic and nature problem of the society or of the world. The research paper refers to the surveys and observation of every individual in a group. It is one way of showing the outputs of every member in order to create great research with a knowledgeable content. The possible outcome of a research reflects the ability of every student on how to observe particular problem. The topic that we have chosen is burning of fossil fuels (effects, causes and prevention). It opens our hearts and minds on the possible effects or outcomes that may happen in our environment if these thing will continuously arise. The damaged has been done in several parts of the world. The only thing we must do is to initiate other ideas that may convert the effects of burning of fossil fuel into a suitable one. The next pages of this research will explain other alternative ways to get energy or electricity without using or burning fossil fuels. As we continue to understand these things in this world, let’s put in our mind first that the imbalance of our nature can affects great percentage of our life not just here in the present but also to the next generation to come. OBJECTIVES:...
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...Environmental Protection Agency (EPA) has proposed a suite of commonsense requirements that together will help combat climate change, reduce air pollution that harms public health, and provide greater certainty about Clean Air Act permitting requirements for the oil and natural gas industry. The proposals are part of the agency’s broad-based strategy under the President’s Climate Action Plan to reduce emissions of the potent greenhouse gas methane and smog-forming volatile organic compounds from this rapidly growing industry. The proposal will complement rules the agency issued in 2012 to reduce pollution from the oil and natural gas industry while helping ensure that development of these energy resources is safe and responsible. The World Health Organization defines air pollution as “the presence of material in the air in such concentration which are harmful to man and his environment.” In fact air pollution is the occurrence or addition of foreign particles, gases, and other pollutants into the air which have an adverse effect on human beings, animals, and vegetation. The various causes of air pollution are: combustion of natural gas, coal and wood in industries, automobiles, aircraft, railways, thermal plants, agricultural burning, kitchens, metallurgical processing (mineral dust, fumes containing fluorides, sulphides and metallic pollutants like lead, chromium, nickel, beryllium, arsenic vanadium, cadmium, zinc, mercury), processing industries like cotton textiles...
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...The sector overview and Major players The Indian Pharmaceutical industry is highly fragmented with about 24,000 players (around 330 in the organised sector). The top ten companies make up for more than a third of the market. The Indian pharma industry (IPM) grew by 16% YoY in 2012 to ` 629 bn. It accounts for about 1.4% of the world's pharma industry in value terms and 10% in volume terms. Besides the domestic market, Indian pharma companies also have a large chunk of their revenues coming from exports. While some are focusing on the generics market in the US, Europe and semi-regulated markets, others are focusing on custom manufacturing for innovator companies. Biopharmaceuticals is also increasingly becoming an area of interest given the complexity in manufacture and limited competition. The drug price control order (DPCO) continues to be a menace for the industry. There are three tiers of regulations – on bulk drugs, on formulations and on overall profitability. This has made the profitability of the sector susceptible to the whims and fancies of the pricing authority. In connotation, with pricing policy of 354 drugs, NLEM (National list of essential medicines) was released, which covered the list of the drugs which the authority intends to put under price control. The policy has been stiffly opposed by the pharmaceutical industry. Introduction of GDUFA (Generic drug user fee Act) in US. As per this act, the generic companies are required to pay user fees to USFDA, for...
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...insight commentary Virtual screening of chemical libraries Brian K. Shoichet Department of Pharmaceutical Chemistry, University of California, 600 16th Street, San Francisco, California 94143-2240, USA (e-mail: shoichet@cgl.ucsf.edu) Virtual screening uses computer-based methods to discover new ligands on the basis of biological structures. Although widely heralded in the 1970s and 1980s, the technique has since struggled to meet its initial promise, and drug discovery remains dominated by empirical screening. Recent successes in predicting new ligands and their receptor-bound structures, and better rates of ligand discovery compared to empirical screening, have re-ignited interest in virtual screening, which is now widely used in drug discovery, albeit on a more limited scale than empirical screening. T he dominant technique for the identification of new lead compounds in drug discovery is the physical screening of large libraries of chemicals against a biological target (high-throughput screening). An alternative approach, known as virtual screening, is to computationally screen large libraries of chemicals for compounds that complement targets of known structure, and experimentally test those that are predicted to bind well. Such receptor-based virtual screening faces several fundamental challenges, including sampling the various conformations of flexible molecules and calculating absolute binding energies in an aqueous environment. Nevertheless, the field has...
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...consists of solid and liquid aerosols suspended in the atmosphere. These arise from the burning of coal and from industrial processes. It hastens the erosion of building materials and the corrosion of metals, interferes with the human respiratory system, and brings toxic materials into the body. The small particles cause chronic bronchitis, bronchial asthma, emphysema and lung cancer. The second type is sulfur oxides, which come from the burning of coal and industrial processes. Damage to materials, to vegetation, and to the human respiratory system are caused by the acid nature of oxides. The third type of pollutant is carbon monoxide. Carbon monoxide is a colorless, odourless, tasteless gas against which humans have no protection. Haemoglobin, which is in the blood, combines with carbon monoxide and carries less oxygen to body tissues causing health and heart effects. Some health problems come from the exhaust fumes leaking into the interior of the automobile. Several hundred Americans die from CO poisoning each year. The fourth type is hydrocarbons, which are chemical, compounds containing only carbon and hydrogen. Hydrocarbons also arise from gasoline-powered vehicles and from industrial processes. Hydrocarbons are released when fuel in the engine burns partially. When hydrocarbons come in contact with sunlight they form ground level ozone. Ground level ozone is a major ingredient in the formation of smog. Ground level ozone is responsible for irritating eyes, damaging lungs...
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...Volume 3, number 2 What is critical appraisal? Sponsored by an educational grant from AVENTIS Pharma Alison Hill BSC FFPHM FRCP Director, and Claire Spittlehouse BSc Business Manager, Critical Appraisal Skills Programme, Institute of Health Sciences, Oxford q Critical appraisal is the process of systematically examining research evidence to assess its validity, results and relevance before using it to inform a decision. q Critical appraisal is an essential part of evidence-based clinical practice that includes the process of systematically finding, appraising and acting on evidence of effectiveness. q Critical appraisal allows us to make sense of research evidence and thus begins to close the gap between research and practice. q Randomised controlled trials can minimise bias and use the most appropriate design for studying the effectiveness of a specific intervention or treatment. q Systematic reviews are particularly useful because they usually contain an explicit statement of the objectives, materials and methods, and should be conducted according to explicit and reproducible methodology. q Randomised controlled trials and systematic reviews are not automatically of good quality and should be appraised critically. www.evidence-based-medicine.co.uk Prescribing information is on page 8 1 What is critical appraisal What is critical appraisal? Critical appraisal is one step in the process of evidence-based clinical practice. Evidencebased clinical practice...
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...2 AQA BIOL5: The synoptic essay AQA A2 Biology: Writing the Synoptic Essay by Dr Robert Mitchell CT Publications Copyright © Dr Robert Mitchell 2010 www.ctpublications.co.uk 0800 040 7901 Dr Robert Mitchell A catalogue record for this book is available from the British Library ISBN 978-1-907769-02-3 First published in May 2010 by CT Publications Copyright © Dr Robert Mitchell 2010 The right of Robert Mitchell to be identified as the author of this work has been asserted by him in accordance with the Copyright and Designs and Patents Act 1988. All rights reserved. No part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording or any information storage and retrieval system, without permission in writing from the publisher at the address below. Published in 2010 by CT Publications* 40 Higher Bridge Street Bolton Greater Manchester BL1 2HA Edition 10 9 8 7 6 5 4 3 2 1 *CT Publications is owned by Chemistry Tutorials located at the same address. Copyright © Dr Robert Mitchell 2010 www.biologytutorials.co.uk 0800 040 7901 3 4 AQA BIOL5: The synoptic essay CONTENTS 1. Be aware of the task you face ............................................................................ 6 What is Synoptic? ........................................................................................... 6 Will I have to learn everything? ..............
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...NEURO-MARKETING Project work Paper No. – CH 6.3 (b) UNDER THE SUPERVISION OF MS. VARTIKA KHANDELWAL DECLARATION BY STUDENT This is to certify that the material embodied in this study entitled “NEURO-MARKETING” is based on my own research work and my indebtedness to other work/publications has been acknowledged at the relevant places. This study has not been submitted elsewhere either wholly or in part for award of any degree. DIVANSHU SAXENA DECLARATION BY TEACHER INCHARGE This is to certify that the project titled “NEURO - MARKETING” done by DIVANSHU SAXENA is a part of his/her academic curriculum for the degree of B.Com (H). It has no commercial implication and is done only for academic purpose. Ms.Vartika Khandelwal Ms. Aruna Jha (Mentor) (Teacher in charge) ACKNOWLEDGEMENT I express my deep sense of gratitude to my mentor Ms. Vartika Khandelwal for encouraging me to take the literature review on the topic of Neuro-Marketing as a part of my Bachelor of Commerce’s curriculum for semester VI. I am very much thankful to her for valuable guidance, keen interest and encouragement at various stages of my literature review work. I would further like to thank my Marketing teacher Ms. Monika Bansal whose guidance and suggestion contributed immensely to the evolution of my ideas on the project. I would also like to thank my friends and family without whom the project would have been a distant reality. Divanshu Saxena ...
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...P1 Public Health Strategies in the UK and their origins. In this article I am going to describe the key features of public health strategies as they relate to current times in the UK. -Monitoring the health status of the population. This strategy involves keeping track of people’s health/keeping an eye on everyone though statics. By tracking changes in the health of the population health professionals are able to alert people to potential problems, for example regular check-ups, at doctors for asthma or Dentist to check up on teeth and make sure they are in good condition plus Orthodontic. Also the NHS provide a free midlife MOT to check people aged between 40-74, to make sure they are in good health and to help reduce the number of elderly who suffer with high blood pressure. Also for HIV, they monitor the health of the population with HIV tracking the number of people with HIV within the population. This helps the NHS find out the population of people with HIV in order for them to take further actions. -Identifying the health needs of the population. This strategy involves identifying health needs, including those that are common problems/ illness that are considered a major problem. For example identifying the illness and providing support through services or medicine, advert are a great way that can get you aware, and provide you with health awareness that is common in the population. Doctors for example monitor the health status of...
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...its new meaning which focuses on the satisfaction of customers' needs and wants. Sales cannot be performed before creating a product. Marketing starts long before a product is created by a company. It encompasses activities carried out by managers in order to assess the wants, define their scope, and find out whether profits are possible or not. Marketing activities continue over the entire lifetime of a product, trying to attract new clients and keep the existing ones by improving the product's quality and appeal, using the insights into sales results and the management of repeated orders. But what is Neuro-Marketing? To understand this, we shall look at the following research, which in a way formed the framework for Neuro-Marketing concepts and Techniques. Montague carried out an interesting research based on the fact that the Pepsi and Coca-Cola drinks have an almost identical chemical composition. They examined the influence of perception on the preferences of...
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