...Biology Semester 1 Research Project Cellular Process Meagan Baggett 4th Period The endosymbiotic theory explains how eukaryotic cells may have evolved from prokaryotic cells. Symbiosis is a close relationship between two different organisms. The discovery of the endosymbiotic theory took hundreds of years to be considered as real and was eventually it was finalized. The endosymbiotic theory is believed to be first introduced and described by Andreas Schimper in 1883. Schimper was a German botanist and phytogeographer. He was born on May 12, 1856 and he passed away on September 9, 1901, at the age of forty-five. After studying at the University of Strassburg from 1874 to 1878, in the process acquiring his Ph.D, He left Germany...
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...Scientific Report Name: Joh Sturdy Title: To investigate the effect of exercise on breathing. Aim: The aim of this experiment is to find out the effect of exercise on the respiratory system Introduction: During exercise, our muscle cells respire more than when we are resting. Exercise is carried out by increasing the respiration rate and the heart rate. (BBC Bitesize 2014) Exercise occurs when the muscles contract and relax which create movement. Energy for cells is created in the mitochondria of every cell, through the process of cellular respiration (Glucose + Oxygen -----> Carbon Dioxide + Water + ENERGY). The Mitochondria is known as the "powerhouse" of all cells and they act like...
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...and 59% for stroke and heart disease respectively while it has been static for cancer with no decrease in death rates inspite of extensive research and treatment efforts. This suggests that something is wrong about cancer treatment. The term “Five year survival rate” hides within it our sad story of not being able to find a permanent cure to cancer. Chemotherapy, radiotherapy, surgery are not curative but symptomatic therapies merely extending our lives. Our scientists inspite of doing researches involving billions of money and publishing an amazing 1.5 million papers have not found a cure to cancer. We have been only able to increase the five year survival rates from 48.75 % in 1975 to 69% in 2007, pointing to us that there is something wrong. Radiotherapy and chemotherapy increases risk of leukemias and solid tumors, targeted therapy to melanoma and stem cell transplant can result in second cancers. The irony of cancer treatment causing cancers and the unending list of severe side effects from vomiting, alopecia to infertility and immunocompromised state gives a sickening feeling about the cancer management we are following. 90% of the time the cause of death in cancer is metastases. We don’t have any weaponry to attack them except palliative pain treatment. Its not even in our priority list with only less than 0.5% of research projects on metastases. Not targeting the biggest monster i.e. metastases makes me feel wrong about our current cancer management. Running...
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...Co-translational localization to the rough ER Research Question • IL-1, a secreted lymphokine that indudes fever upon infection, lacks a signal sequence from its primary amino acid sequence. Devise an approach that can be used to ascertain the mechanism of IL-1 secretion. Overview • Eukaryotic cells are structurally and functionally compartmentalized. • This provides a favorable chemical environment for specialized reactions to take place in a large cell. • Specialization is provided by proteins that are sorted (localized) to these compartments. Signal sequences for secretion Organelles are specific for eukaryotes Organelles have specific fxns provided by the proteins moved specifically to those organelles Translocation: moving a protein across a membrane into an organelle Protein sorting mechanisms [pic] Another word that people use for this subject is protein sorting: this means that all the proteins are made in free rib or rough er Cell has to sort and send out to right location Transport for protein Cytosol to nucleus: gated transported: nuclear pore made of a bunch of proteins and regulated by GTP hydrolysis; the whole proteins was already synthesized by free ribosomes and moved through nuclear membrane through the gate Proteins always first in cytosol. Proteins from cytosol to ER then into mitochondria or chloroplast or peroxisomes etc depending on where they are going Through a transmembrane transport using and signal sequence...
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...New insights into how cells cope with stress could help combat neurological diseases and reduce the ravages of aging. Scientists have known for years that moderate stressors, such as a calorie-restricted diet, increase lifespan in a variety of organisms. Now new research is illuminating how this works at the molecular level. A particular protein is key in regulating at least one aspect of the stress response and may be a good model for anti-aging drugs. "What we have here is an essential protective pathway that now looks like a very effective therapeutic target," said biologist Richard Morimoto of Northwestern University. Most research on this protein, called sirtuin1 (SIRT1), has concentrated on its ability to regulate and protect mitochondria — cellular power generators that are corroded over time by reactive oxygen molecules. But SIRT1 also protects DNA in the cell nucleus. Morimoto’s findings, published Thursday in Science, give a precise mechanical explanation for the effects. Cells have evolved a particular response to stay alive in adverse conditions. When a cell starts getting too hot, too hungry or too oxygen-deprived, certain proteins migrate into the nucleus. There, they latch onto sections of DNA and cause heat-shock proteins to be produced. Heatshock proteins — so named because they were first discovered in cells experiencing high temperatures — cruise around the cell, fixing damaged or improperly folded proteins. "Proteins are very delicate," Morimoto said. "Any...
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...is used by scientists to describe the variety of processes used in making duplicates of biological materials. This paper will discuss the embryonic cells and pronucleus taking into accounts their application to human cloning. Caenorhadditis elegans and Drosophila melanogaster will also be discussed together with application of Hardy-Weinberg equilibrium. Embryonic stem cell has been applied in human cloning through human cloning for biomedical research whereby cloned cells are produced and used in individual patients suffering from diseases like Parkinson’s disease and type 1 diabetes (Fairbanks, 2004). This discovery has been used to develop embryos thus making important steps for medicine. Cloned embryos have been used widely as sources of stem cells, which have been developed to make new heart muscles, bone, brain tissues and other type of cells in the body. The stem cells have provided a breakthrough in medicine by creating new tissues that might be able to heal the damage caused by heart attack or repair severed spinal cord (Fairbanks, 2004). There are trials of utilizing stem cells from donated embryos to try and restore people’s eye sights. The donated cells are cloned to match the patient so that they would not be rejected by the body. With this kind of research various ethical and moral considerations have emerged, one of them being that this research involves deliberate production, use and destruction of cloned human embryo that could be used in attempts to produce...
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...Anatomy and Physiology 2, SCI 136 Research project # 40904000 Muscular Dystrophy Definition Muscular dystrophy (MD) refers to a group of more than 30 genetic diseases that cause progressive weakness and degeneration of skeletal muscles used during voluntary movement. The word dystrophy is derived from the Greek dys, which means "difficult" or "faulty," and troph, or "nourish." These disorders vary in age of onset, severity, and pattern of affected muscles. All forms of MD grow worse as muscles progressively degenerate and weaken. Many patients eventually lose the ability to walk (“National Institute,” 2011). Some types of MD also affect the heart, gastrointestinal system, endocrine glands, spine, eyes, brain, and other organs. Respiratory and cardiac diseases may occur, and some patients may develop a swallowing disorder. MD is not contagious and cannot be brought on by injury or activity (“National Institute,” 2011). Method(s) of diagnosis Muscular dystrophies are diagnosed through both the patient’s medical history and a complete family history to determine if the muscle disease is secondary to a disease affecting other tissues or organs or is an inherited condition. It is also important to rule out any muscle weakness resulting from prior surgery, exposure to toxins, current medications that may affect the patient's functional status, and any acquired muscle diseases. Thorough clinical and neurological exams can rule out disorders of the central and/or...
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...that energy drinks have become the latest fad - from tired college students to business professionals and children. While there may be countless different reasons for the consumption of these drinks, the question remains, are energy drinks ultimately harmful to your health? As a college student who has to stay up late at times to study, I myself have had to use energy drinks. However, I found myself wondering what was inside these drinks and when I looked at the ingredients, I realized I didn’t recognize many of the ingredients that I was drinking. As I try to be very cautious with my health and the things I consume, I wanted to further explore what was in these energy drinks and if they were ultimately harmful to my health. To begin my research, I searched Google to see whether these energy drinks were harmful to my health. I found an article by the McKinley Health Center, published in 2011, and titled “What’s the Buzz with Energy Drinks?” This article discussed how the amount of caffeine in energy drinks is usually much higher than the Food and Drug Administration allows in cola beverages. A high intake of caffeine may have minor effects in the short term, however, in the long term, it can have more substantial and detrimental effects such as bone density, harming unborn children, and weight gain. This article provided some good evidence to the detrimental effects of energy drinks; however, I wanted to see if I could find an article with a positive perspective on energy drinks...
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...Hassan 1 Hussein Hassan Mr. Horn AP Seminar February 2 2015 The Perfect Human: The Flaws in Modern Eugenics With global technologies rapidly advancing, specifically those based in the field of genetics, one might wonder where humanity is headed in terms of their offspring. The answer? Modern eugenics. Francis Galton's eugenics, centered around forced sterilization and selective breeding to eliminate undesirable traits and foster the spread of more advantageous ones (Galton), is dead. However, the idea of focusing on one’s inherited genes to eliminate passed down diseases is alive and well, albeit in a more “modern” fashion. Is modern eugenics the right way of the future for humanity? To what extent should modern eugenics be viable? Before ambitious genetic projects had begun, such as the Human Genome Project which mapped out the entirety of the human genome (Genome.gov), the only way to tamper with an individual’s genes was through their parents. Gregor Mendel earned the moniker “The Father of Genetics” because of his experiments involving the breeding of plants in the mid 19th century (Biography.com). However, modern eugenics focuses on the genes of child more than the parents through abortions and the genetic altering of the embryo to achieve the desired results. This can be achieved through a process called genetic screening, which observes an embryo’s chromosomes for any lapses or breaks (Galloway a). Embryo’s that show signs of a genetic disorders...
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...Blood Doping Biology Research Paper Samantha Reid University Seven time consecutive Tour De France champion and yellow rubber band seller of the decade openly admitted to blood doping. His name was Lance Armstrong and not only did he live through cancer, but he was one of the greatest athletes the world has ever known. His list of achievement goes on until his banishment for professional racing and the stripping of his titles. He admitted to using banned substances including steroids and blood doping in an interview with Oprah Winfrey on January 17, 2013. Why would a man with so many accomplishments cheat the system with prohibited procedures and the use of illegal performance drugs? The three topics that rise in answering why Lance Armstrong blood doped is explaining what blood doping is, the advantage and disadvantages of it and drug use in profession sports. To describe what blood doping is one must first understand some key terms. Hemoglobin is a red protein responsible for carrying oxygen in your blood. Another key term is the cardiovascular system and this is an organ system that distributes the blood throughout the body to deliver nutrients and remove waste. And the respiratory system is the organ system that carries out gas exchange in your body. These three things all work together hand in hand like a smooth operating clock. The respiratory system gets the oxygen from the air and transports it to the blood carried in the hemoglobin. The oxygen enriched hemoglobin...
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...M1,D1)You are an advisor in your local sports centre and you have been asked to design and produce an information booklet to explain to clients how the body requires and utilises energy. This should include:Produce a written report on the body’s response to exercise. The report will be based on primary and secondary research. The report will include:Task 5 (P5,M2,D2) 1. An explanation of the concept of homeostasis and its role in exercise and healthy functioning of the body. 2. Measurements collected from practical work involving physical activity and your interpretation of them together with comments on the validity of the data collected.Task 6 (P6)Complete exercise programme and complete data form and graphs sheets | The Brief | Task 1 (P1)Using a large piece of paper, produce an annotated poster of a cell as it is seen under the microscope. You must include the following; * Organelles – nucleus, cytoplasm, mitochondria, smooth and rough endoplasmic reticula * Golgi apparatus * LysosomesThe notes accompanying the labels should include the main activities carried out by the organelles. Cells: cell membrane, nucleus, cytoplasm; organelles – mitochondria, endoplasmic reticulum (smooth and rough), Golgi apparatus, lysosomeTask 2...
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...energy. Subdisciplines of biology are recognized on the basis of the scale at which organisms are studied and the methods used to study them: biochemistry examines the rudimentary chemistry of life; molecular biology studies the complex interactions of systems of biological molecules; cellular biology examines the basic building block of all life, the cell; physiology examines the physical and chemical functions of the tissues, organs, and organ systems of an organism; and ecology examines how various organisms interact and associate with their environment.[3] Contents [hide] * 1 History * 2 Foundations of modern biology * 2.1 Cell theory * 2.2 Evolution * 2.3 Genetics * 2.4 Homeostasis * 2.5 Energy * 3 Research * 3.1 Structural * 3.2 Physiological * 3.3 Evolutionary * 3.4 Systematics * 3.5 Ecology * 4...
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...free Mg concentration ([Mg]i) was measured in ferret ventricular muscle using singlebarrelled Mg-sensitive micro-electrodes. The electrodes were calibrated in solutions containing the [K]i and [Na]i measured in this tissue. In thirteen measurements from seven experiments conforming to strict criteria for calibration and penetration the estimated mean [Mg]i was 04 mmol/l. This is to be regarded as an upper limit since it was estimated by linear extrapolation of the calibration curve. INTRODUCTION Ionized Mg plays an essential role in the regulation of a large number of cellular functions. It is a co-factor in many enzymatic reactions, influences tension development in muscle and modulates amongst others the ionic transport systems in mitochondria (see reviews by Gunther, 1977; Shine, 1979; and Ackerman & Nicholls, 1983). Despite its importance in cellular mechanisms, estimations of the free Mg ([Mg]i) by various methods range from 0- 1 mmol/l to 6 mmol/l (reviews: Flatman, 1984; Gupta, Gupta & Moore, 1984) mainly because of the lack of a simple direct method for its measurement. Direct measurement of [Mg]i is now possible using micro-electrodes filled with the Mg resin described by Lanter, Erne, Ammann & Simon (1980) and measurements have been carried out in both cardiac and skeletal muscle (Hess, Metzger & Weingart, 1982; Lopez, Alamo, Caputo, Vergara & DiPolo, 1984), and in nerve cells of Helix aspersa (AlvarezLeefmans, Gamifno & Rink, 1984). This resin has however, the disadvantage...
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...Huntington's: The Anticipation that Kills After doing research on the effects of the disorder Huntington’s disease, it is easy to understand what a disease like Huntington’s will do to an individual way of life. Imagine being thirty years old with a good job, a loving spouse, maybe a couple of kids and an all-around pretty good life. Then imagine one day your boss writes you up and sends you home because he/she suspects you of being intoxicated. A person in this situation could, in months and years to come, learn from a simple blood test that he/she is the victim of a genetic disorder called Huntington’s disease. The ramifications of this illness are endless and affect not only the individual with the disorder but entire families and communities as well. At this time there is no cure or even any significantly effective treatment. However, as with many genetic disorders, research is being done in in this day in age that may promise to one day lead us to such treatment or cure. Huntington’s disease is a neurodegenerative or genetic disorder that affects muscle coordination and some cognitive functions, typically becoming noticeable in middle age. It is much more common in people of Western Europe descent than in those from Asia or Africa. The disease is caused by dominant mutation on either of the two copies of a specific gene, located on chromosome 4. The Huntington gene normally provides the genetic code for a protein that is also called Huntingtin. The mutation of the Huntingtin...
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...trademarks or registered trademarks of Microsoft Corporation. All other trademarks and registered trademarks are the property of their respective owners and are hereby acknowledged. Do not make illegal, unauthorized copies of the PhraseBook. The PhraseBook and digital version are protected by copyright law and international treaties. The publisher and authors have striven to ensure the accuracy and correctness of the PhraseBook; however, they can accept no responsibility for any loss or inconvenience as a consequence of use, information or advice contained in the PhraseBook. PhraseBook versions ISBN 978-1-903384-02-2 paperback ISBN 978-1-903384-01-5 digital version (download) ISBN 978-1-903384-00-8 digital multiple user version (CD-ROM) for research groups, departments and universities For PhraseBooks and English books for education, visit EnglishforResearch.com ▪ EnglishforStudents.com ▪ EnglishforSchool.com Contents Contents End User Licence...
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