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The Diathesis-Stress Model Of Schizophrenia

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Schizophrenia is defined as a psychotic disorder which influences the way people behave, think and act. An individual experiencing this disorder possesses feelings and thoughts that do not work together ordinarily. It is “an abnormal disintegration of mental functions” (Gleitman, Gross & Reisberg, 2011). One important point in the development and success of the treatment of schizophrenia is discovering the sole cause of the disorder. The diathesis-stress model of schizophrenia aims to solve this issue. This psychological theory “states that what is genetically inherited is a diathesis, or predisposition, to schizophrenia, but that this predisposition must be combined with environmental stress for the disorder actually to develop” (Bootzin & …show more content…
Although cannabis is “the most widely used illicit drug in the world” (Caspi et al., 2005), worldwide evidence suggests that it is a risk factor in the emergence of schizophrenia. In the year 2005, Caspi tested why cannabis use among teenagers leads to the development of the disorder in some cases but not in others. Of course, the self-report measures used in this study could have added a bias to the results. One extremely positive aspect of the study was the fact that the interviewers had no knowledge of the individual’s history with regards to cannabis use. Results of the study found that those adolescents who had the COMT (catechol-O-methyltransferase) valine allele present were more likely to develop schizophrenia following their continuous use of cannabis. This illustrates the idea that inheritance plays a role in the development of schizophrenia. However, the fact that this gene is only activated by the use of cannabis indicates that the emergence of the disorder is not solely influenced by genetics. “This study provides evidence that a functional polymorphism in the COMT gene interacted with adolescent-onset cannabis use to predict the emergence of adult psychosis” (Caspi et al., 2005). These findings also depict the gene and environment interaction that is emphasised by the diathesis-stress model of

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